Is Pelvic Lymph Node Dissection Necessary in Patients with a Serum PSA<10ng/ml Undergoing Radical Prostatectomy for Prostate Cancer?

OBJECTIVE: Controversy persists concerning the role of pelvic lymph node dissection (PLND) in patients with preoperative PSA values <10ng/ml undergoing treatment for prostate cancer with a curative intent. The aim of this study was to determine the incidence of lymph node metastasis in this subgroup of patients. METHODS: Patients with clinically localized prostate cancer and a serum PSA<10ng/ml, without neoadjuvant hormonal or radiotherapy, with negative staging examinations who underwent radical retropubic prostatectomy with bilateral extended PLND and with >/=10 lymph nodes detected by the pathologist in the surgical specimen, were included in the study. RESULTS: A total of 231 patients with a median serum PSA of 6.7ng/ml (range 0.4-9.98) and a median age of 62 years (range 44-76) were evaluated. A median of 20 (range 10-72) nodes were removed per patient. Positive nodes were found in 26 of 231 patients (11%), the majority of which (81%) had a Gleason score >/=7 in the surgical specimen. Of the patients with a Gleason score >/=7 in the prostatectomy specimen 25% had positive nodes, whereas only 3% with a Gleason score /=7 in the prostatectomy specimen was 25% after extended PLND. It seems that in this patient group extended PLND, including removal of nodes along the internal iliac vessels, is warranted.

Tefillôt Yešûrûn : metûrgāmôt aškenazzît mîlā be-mîlā mesuddār bi-šlēmût has-siddûr ... izraeliṭišez gebeṭbuch miṭ werṭlicher iberzeṭtzung

Übers. d. Hauptsacht.: Gebete Israels

Ernst Mäßl von Satz auß Böhaim : Ein Riemer und ein Approbirter Meister deß Langen Schwerdts von der Feder, Seines Alters 27. Jahr

Bibliogr. Nachweis: Allg. Portr.Kat. Nr. 34722

(Table 1, page 605) Chemistry of concretions from Grand Lake (GL) and Ship Harbour Lake (SH), Nova Scotia and Mosque Lake (ML), Ontario

Studies by optical microscopy, x-ray diffraction, and electron probe techniques of ferromanganese concretions from three Canadian lakes reveal chemical banding of amorphous hydrated iron and manganese oxides. The average ratio of iron to manganese in concretions from these lakes varies from 0.43 to 2.56. The concentrations of cobalt, nickel, copper, and lead are one to two orders of magnitude below those reported for oceanic ferromanganese concretions.

Project Neos; a generalized study of processes for the realization of esign configurations in materials. [Final] technical documentary report no. ML-TDR-64-311. MTD project no.7-867.

Mode of access: Internet.

Emblemes ou devises chretiennes : ouvrage mêlé de prose & de vers, et enrichi de figures ...

Imperfect: lacking leaf L6 (emblem 62).

The structural stability of welds in columbium alloys. Technical documentary report no. ML-TDR-64-210.

Cover title.

Hugsvinns-mál, ásamt þeirra látinska frumriti,

At head of title: Skóla hátid í minníngu fædíngar-dags vors allranádugasta konúngs Fridriks Sjøtta, þann 28de janúarii 1831. er haldin verdur þann lta febr. 1831. bodud af kénnurum Bessastada skóla.

Valentine, ou La chute des feuilles; drame en deux actes, mêlé de chants,

Mode of access: Internet.