Antidepressants and breast-feeding : a review of the literature

For every antidepressant so far investigated in the breast milk of mothers prescribed these medications, findings indicate that some amount of drug will be excreted into the breast milk. Nursing infants will be exposed to some, usually a very low, amount of drug and drugmetabolites. Levels of drug exposure to infants for the many antidepressants available are examined, discussing milk to plasma drug concentration ratios and the infant dose as a percentage of thematernal dose. Drug concentrations in infant plasma and adverse effects of drug exposures to infants are reviewed. Factors influencing the decision on whether to breast or bottle feed an infant nursed by a mother taking antidepressants are discussed, concluding that the decision needs to be made on an individual basis. The lactating mother, in consultation with her doctor, should be in a position to make an informed decision on whether or not to breast feed. Under certain circumstances the decision to bottle feed may be wise, but more commonly the advantages of breast-feeding will outweigh the very low risk of an adverse event from drug exposure to the infant.

Children's literature in a global age : transnational and local identities

This essay explores the concept of transnationalism, defi ning this term in relation both to the lived experience of transnational subjects, and to transnational texts for children. It argues that rhetorics of globalization have over-emphasized the impact and signifi cance of global cultural and economic fl ows, although the production of children’s books is to some extent shaped by the internationalization of publishing houses and markets. The concept of transnationalism provides a way of thinking about how children’s texts address and are informed by diverse, complex infl uences, sometimes from a variety of cultures and languages. Transnationalism is not a new phenomenon but is visible in colonial texts which are shaped both by the particular, local ideologies of colonial nations, and also by the common concerns and interests of such nations. The essay draws on two contemporary texts to illustrate the workings of transnationalism: the fi lm Howl’s Moving Castle, and Shaun Tan’s picture book The Arrival. It concludes by considering the concept of transnational literacy as a way of approaching scholarship and teaching in children’s literature.