Biological impact assessment of nanomaterial used in nanomedicine. Introduction to the NanoTEST project.

Therapeutic nanoparticles (NPs) are used in nanomedicine as drug carriers or imaging agents, providing increased selectivity/specificity for diseased tissues. The first NPs in nanomedicine were developed for increasing the efficacy of known drugs displaying dose-limiting toxicity and poor bioavailability and for enhancing disease detection. Nanotechnologies have gained much interest owing to their huge potential for applications in industry and medicine. It is necessary to ensure and control the biocompatibility of the components of therapeutic NPs to guarantee that intrinsic toxicity does not overtake the benefits. In addition to monitoring their toxicity in vitro, in vivo and in silico, it is also necessary to understand their distribution in the human body, their biodegradation and excretion routes and dispersion in the environment. Therefore, a deep understanding of their interactions with living tissues and of their possible effects in the human (and animal) body is required for the safe use of nanoparticulate formulations. Obtaining this information was the main aim of the NanoTEST project, and the goals of the reports collected together in this special issue are to summarise the observations and results obtained by the participating research teams and to provide methodological tools for evaluating the biological impact of NPs.

VariScan Software

VariScan is a software package for the analysis of DNA sequence polymorphisms at the whole genome scale. Among other features, the software:(1) can conduct many population genetic analyses; (2) incorporates a multiresolution wavelet transform-based method that allows capturing relevant information from DNA polymorphism data; and (3) it facilitates the visualization of the results in the most commonly used genome browsers.

Web, firewall y Linux en el ICJCE

Con este proyecto se quiere dotar al Instituto de Censores Jurados de Cuentas de España (ICJCE) de las actuales mejoras existentes en el entorno del software libre.

Estudio de implantación de red y servicios Linux

Creación de una estructura de red que permita redireccionar el tráfico entre las redes WLAN y hacia Internet desde un punto central de un centro educativo, de forma que sea dinámico realizar cambios sobre la configuración desde una sola máquina.

Desenvolupament des de zero d'un sistema Linux per ser instal·lat als ordinadors de les aules ordinàries d'un institut de secundària

Exposició dels passos que cal seguir per construir un sistema GNU/Linux adreçat a les aules dels instituts de secundària prenent com a base Linux From Scratch versió 7.5.

Estudi comparatiu d'eines de distribucions GNU/Linux orientades a seguretat de xarxes

Aquest projecte pretén estudiar i analitzar tres distribucions Linux especialitzades en seguretat de xarxes. En aquest estudi es descriuran les característiques tècniques de cada distribució així com la classificació de les seves eines principals.