Remote monitoring system enabling cloud technology upon smart phones and inertial sensors for human kinematics

Stroke is a common neurological condition which is becoming increasingly common as the population ages. This entails healthcare monitoring systems suitable for home use, with remote access for medical professionals and emergency responders. The mobile phone is becoming the easy access tool for self-evaluation of health, but it is hindered by inherent problems including computational power and storage capacity. This research proposes a novel cloud based architecture of a biomedical system for a wearable motion kinematic analysis system which mitigates the above mentioned deficiencies of mobile devices. The system contains three subsystems: 1. Bio Kin WMS for measuring the acceleration and rotation of movement 2. Bio Kin Mobi for Mobile phone based data gathering and visualization 3. Bio Kin Cloud for data intensive computations and storage. The system is implemented as a web system and an android based mobile application. The web system communicates with the mobile application using an encrypted data structure containing sensor data and identifiable headings. The raw data, according to identifiable headings, is stored in the Amazon Relational Database Service which is automatically backed up daily. The system was deployed and tested in Amazon Web Services.

Titanium dioxide nanotube films for electrochemical supercapacitors: Biocompatibility and operation in an electrolyte based on a physiological fluid

Growing interest in developing devices that can be implantable or wearable requires the identification of suitable materials for the components of these devices. Electrochemical supercapacitors are not the exception in this trend, and identifying electrode materials that can be not only suitable for the capacitive device but also biocompatible at the same time is important. In addition, it would be advantageous if physiological fluids could be used instead of more conventional (and often corrosive) electrolytes for implantable or wearable supercapacitors. In this study, we assess the biocompatibility of films of anodized TiO2 nanotubes subjected to the subsequent annealing in Ar atmosphere and evaluate their capacitive performance in a physiological liquid. A biocompatibility test tracking cell proliferation on TiO2 nanotube electrodes and electrochemical tests in 0.01 M phosphate-buffered saline solution are discussed. It is expected that the study will stimulate further developments in this area.

Extending support to customised multi-point haptic devices in CHAI3D

 CHAI3D is a widely accepted haptic SDK in the society because it is open-source and provides support to devices from different vendors. In many cases, CHAI3D and its related demos are used for benchmarking various haptic collision and rendering algorithms. However, CHAI3D is designed for off-the-shelf single-point haptic devices only, and it does not provide native support to customised multi-point haptic devices. In this paper, we aim to extend the existing CHAI3D framework and provide a standardized routine to support customised, single/multi-point haptic devices. Our extension aims at two issues: Intra-device communication and Inter-device communication. Therefore, our extension includes an HIP wrapper layer to concurrently handle multiple HIPs of a single device, and a communication layer to concurrently handle multiple position, orientation and force calculations of multiple haptic devices. Our extension runs on top of a custom-built 8-channel device controller, although other offthe shelf controllers can also be integrated easily. Our extension complies with the CHAI3D design framework and advanced provide inter-device communication capabilities for multi-device operations. With straightforward conversion routines, existing CHAI3D demos can be adapted to multi-point demos, supporting real-time parallel collision detection and force rendering.

Biomedical sensing analyzer (BSA) for mobile-health (mHealth)-LTE

The rapid expansion of mobile-based systems, the capabilities of smartphone devices, as well as the radio access and cellular network technologies are the wind beneath the wing of mobile health (mHealth). In this paper, the concept of biomedical sensing analyzer (BSA) is presented, which is a novel framework, devised for sensor-based mHealth applications. The BSA is capable of formulating the Quality of Service (QoS) measurements in an end-to-end sense, covering the entire communication path (wearable sensors, link-technology, smartphone, cell-towers, mobile-cloud, and the end-users). The characterization and formulation of BSA depend on a number of factors, including the deployment of application-specific biomedical sensors, generic link-technologies, collection, aggregation, and prioritization of mHealth data, cellular network based on the Long-Term Evolution (LTE) access technology, and extensive multidimensional delay analyses. The results are studied and analyzed in a LabView 8.5 programming environment.

The characteristics and outcome of infective endocarditis involving implantable cardiac devices

Infection of implantable cardiac electronic devices in particular lead endocarditis (cardiac device infective endocarditis (CDIE)) is an emerging problem with significant morbidity, mortality and health care costs. The epidemiology is characterised with advanced age and health care association in cases presenting within 6 months of implantation. Risk factors include those of the patient, the procedure and the device. Staphylococcal species predominate as the causative organisms. Diagnosis is reliably made by blood cultures and transesophageal echocardiography. Complications include pulmonary and systemic emboli, persistent bacteremia and concomitant valvular involvement. Management includes complete device removal and prolonged antimicrobial therapy. With long-term follow-up to 1 year, the mortality of CDIE is as high as 23 %. It is associated with patient co-morbidities and concomitant valvular involvement and may be prevented by device removal during index admission.

Rectenna circuits for RF energy harvesting in miniature DBS devices.

 Development of an optimum rectenna for radio frequency energy harvesting in miniature head-mountable deep brain stimulation (DBS) devices. The designed miniature rectenna can operate a DBS device without battery for murine preclinical research. The battery-less operation of the device eliminates battery related difficulties.

On optimally reducing power loss in micro-grids with power storage devices

Smart micro-grids can produce 'renewable' energy and store them in power storage devices. Power loss, however, is a significant problem in power exchange among the micro-grids and between the macro-station and individual micro-grids. To optimally reduce the total power losses in such a power grid system, in this paper, a greedy coalition formation algorithm is proposed, which allows the macro-station to coordinate mutual power exchange among the micro-grids and between each micro-grid and the macro-station. Our algorithm optimizes the total power losses across the entire power grid, including the cost of charging and discharging power storage devices and power losses due to power transfers. The algorithm creates exchange pairs among the micro-grids, giving priority to pairs with higher power loss reduction per exchanged power unit. Through computer-based simulations, we demonstrate that the proposed approach significantly reduces the average power loss compared with the conventional noncooperative method. The simulations also demonstrate that the communications overhead of our proposal (due to negotiations aimed at forming coalitions) does not significantly affect the available communication resource. © 2014 IEEE.

Locked nucleic acid aptamer based microfluidic devices for capturing tumor cells

Design and fabrication of novel microfluidic devices for sensitive and specific capture of circulating tumor cells using locked nucleic acid modified aptamers and antibodies targeting EpCAM/Nucleolin expression. These devices also allow re-usability, on-chip characterization of multiple markers and release of viable captured cells for further culture and in vitro characterization for cancer diagnosis, prognosis and therapeutic planning.