En equilibri : Un projecte per a l'autosuficiència econòmica en cultura

El treball explora les alternatives de finançament de la cultura -en el marc de l'economia social i solidària- a partir del projecte concret de La Central del Circ de Barcelona. A través de la proposta d'un festival de circ autogestionat i autosuficient, el projecte concep un marc per a la creació i experimentació de noves fórmules de producció cultural que permetin esquivar la tradicional dependència (econòmica) del sector amb l'administració pública, i apostin per un model de desenvolupament social i ambientalment més sostenible.

Mirada actual des de la psicoanàlisi sobre l'espectre autista : La pràctica entre varis com a alternativa terapéutica en el TEA

Aquest treball es proposa investigar sobre la intervenció psicoanalítica i clínica en el trastorn de l'espectre autista. Es tracta de fer un recorregut crític sobre l'augment de la incidència del trastorn, la discussió sobre la etiologia de la mateixa i les alternatives d'intervenció des de la pràctica entre varis que proposa el psicoanàlisi lacanià.

07043-017 North Fork Maquoketa Final Report

The North Fork Maquoketa River Headwaters (NFMRH) has been identified as impaired by nutrients, episodic slugs of ammonia and sediment. The NFMRH TMDL plan calls for a "phasing approach" to managing water quality when the origin is non-point source contaminants. This project will address phase 1 using a performance reward program for targeted cooperators to improve environmental index scores using cost-share, EQIP practices and flexible management alternatives. Pre-project assessments suggest that rewards should target refined management of erosion-prone fields and farms with livestock populations, which contribute to the P and N loads responsible for fertilizing filamentous algae blooms that depress dissolved oxygen concentrations in the NFMRH. The Phosphorus Index, Soil Conditioning Index and cornstalk nitrate test will be used by producers to determine effective alternatives, such as no-till planting, to reduce nutrient and sediment delivery. These evironmental indexes will be especially useful for livestock producers in the livestock dense watershed. This project will extend a NRCS-sponsored Conservation Innovation Grant currently offered to producers in the Coffee Creek sub-watershed to a three-year, watershed-wide effort that will be necessary to make significant improvements in environmental management.

Investigación de la reincidencia delictiva en los agresores de pareja : el impacto diferencial de la prisión y de las penas alternativas

La reincidencia delictiva es uno de los principales temas de estudio de la Criminología. Una alta tasa de reincidencia es una muestra de que el actual modelo de tratamiento hacia los delincuentes no está dando buenos resultados. Además, podría implicar el fracaso de la prevención especial y del modelo rehabilitador como finalidad principal de la pena, ya que una sociedad que emplea grandes recursos en reinsertar a sus criminales, exige mejores resultados.La aplicación de medidas penales alternativas (en adelante MPA) por parte de los jueces ha aumentado mucho en los últimos años, sobre todo a partir de 2003 (Contreras, 2010). Centrándome en concreto en la pena de trabajos en beneficio de la comunidad (en adelante TBC) y en la suspensión de la pena de prisión (en adelante suspensión), un tema que considero muy interesante investigar es si la aplicación de estas medidas alternativas aportan mejores resultados en términos de reincidencia delictiva que el ingreso en prisión.En esta investigación cuantitativa, la metodología que he utilizado es un diseño cuasi experimental, para comparar el impacto que tienen las MPA como tratamiento en la reincidencia delictiva, utilizando el análisis estadístico de una base de datos de delincuentes condenados por un delito de violencia ocasional contra la pareja. Concretamente, las técnicas utilizadas son el cruce de una serie de variables y el análisis de supervivencia.Partiendo de la hipótesis principal de que las MPA registran menores tasas de reincidencia que la prisión, estudio también la influencia de otras variables como la edad, la nacionalidad y los antecedentes delictivos en el impacto detectado.Los resultados confirman la hipótesis central, pero me llevan rechazar las hipótesis referentes a las demás variables. No obstante, gracias al análisis de esas variables se ha puesto demanifiesto que la variable “antecedentes” tiene una gran validez predictiva de la reincidencia futura y, pese a los problemas y limitaciones reconocidas en la investigación, permiten extraerconclusiones muy interesantes para futuras investigaciones sobre la reincidencia. La conclusión más importante es la evidencia de que las MPA son un tratamiento reductor de la reincidencia a medio y largo plazo, lo cual hace recomendable seguir ampliando y mejorandosu aplicación.

Economic and legal analysis of mandatory non-recourse mortgages with applications to Spain

“The liquidity crisis of the Spanish banks is largely due to the lack of confidence of foreign investors and, therefore, the changes that occur in the legislation should not affect the credibility, stability, legal certainty, predictability that markets expect”.Sergio Nasarre (2011)In the current situation of economic crisis, many people have found they can no longer pay back the mortgage loans that were granted to them in order to purchase a dwelling. It is for this reason that, in light of the economic, political and social problems this poses, our paper studies the state of the Spanish real-estate system and of foreclosure, paying special attention to the solution that has been proposed recently as the best option for debtors that cannot make their mort-gage payments: non-recourse mortgaging. We analyze this proposal from legal and economic perspectives in order to fully understand the effects that this change could imply. At the same time, this paper will also examine several alternatives we believe would ameliorate the situation of mortgage-holders, among them legal reforms, mortgage insurance, and non-recourse mortgaging itself.

Coloquialismo y humor en South Park: análisis del doblaje al español

Este trabajo es un estudio sobre la traducción del coloquialismo y el humor en productos audiovisuales. Tomando como referencia el doblaje al español de South Park, se analizan algunos errores habituales en obras similares y se plantean estrategias de traducción efectivas, tanto a nivel textual como oracional.

Isolation of cardiovascular precursor cells from the human fetal heart.

Weakening of cardiac function in patients with heart failure results from a loss of cardiomyocytes in the damaged heart. Cell replacement therapies as a way to induce myocardial regeneration in humans could represent attractive alternatives to classical drug-based approaches. However, a suitable source of precursor cells, which could produce a functional myocardium after transplantation, remains to be identified. In the present study, we isolated cardiovascular precursor cells from ventricles of human fetal hearts at 12 weeks of gestation. These cells expressed Nkx2.5 but not late cardiac markers such as α-actinin and troponin I. In addition, proliferating cells expressed the mesenchymal stem cell markers CD73, CD90, and CD105. Evidence for functional cardiogenic differentiation in vitro was demonstrated by the upregulation of cardiac gene expression as well as the appearance of cells with organized sarcomeric structures. Importantly, differentiated cells presented spontaneous and triggered calcium signals. Differentiation into smooth muscle cells was also detected. In contrast, precursor cells did not produce endothelial cells. The engraftment and differentiation capacity of green fluorescent protein (GFP)-labeled cardiac precursor cells were then tested in vivo after transfer into the heart of immunodeficient severe combined immunodeficient mice. Engrafted human cells were readily detected in the mouse myocardium. These cells retained their cardiac commitment and differentiated into α-actinin-positive cardiomyocytes. Expression of connexin-43 at the interface between GFP-labeled and endogenous cardiomyocytes indicated that precursor-derived cells connected to the mouse myocardium. Together, these results suggest that human ventricular nonmyocyte cells isolated from fetal hearts represent a suitable source of precursors for cell replacement therapies.

How Wages and Employment Adjust to Trade Liberalization: Quasi-Experimental Evidence from Austria

We study the response of regional employment and nominal wages to trade liberalization, exploiting the natural experiment provided by the opening of Central and Eastern European markets after the fall of the Iron Curtain in 1990. Using data for Austrian municipalities, we examine di¤erential pre- and post-1990 wage and employment growth rates between regions bordering the formerly communist economies and interior regions. If the 'border regions'are de...ned narrowly, within a band of less than 50 kilometers, we can identify statistically signi...cant liberalization e¤ects on both employment and wages. While wages responded earlier than employment, the employment e¤ect over the entire adjustment period is estimated to be around three times as large as the wage e¤ect. The implied slope of the regional labor supply curve can be replicated in an economic geography model that features obstacles to labor migration due to immobile housing and to heterogeneous locational preferences.

Is use of nifurtimox for the treatment of Chagas disease compatible with breast feeding? A population pharmacokinetics analysis.

Introduction Women with Chagas disease receiving treatment with nifurtimox are discouraged from breast feeding. Many patients who would receive treatment with nifurtimox live in extreme poverty, have limited access to resources such as clean water and baby formula and may not have safe alternatives to breast milk. Aim We aimed to estimate, using limited available pharmacokinetics data, potential infant exposure to nifurtimox through breast milk. Methods Original nifurtimox plasma concentrations were obtained from published studies. Pharmacokinetic parameters were estimated using non-linear mixed-effect modelling with NONMEM V.VI. A total of 1000 nifurtimox plasma-concentration profiles were simulated and used to calculate the amount of drug that an infant would be exposed to, if breast fed 150 ml/kg/day. Results Breast milk concentrations on the basis of peak plasma levels (1361 ng/ml) and milk-plasma ratio were estimated. We calculated infant nifurtimox exposure of a breastfed infant of a mother treated with this drug to be below 10% of the maternal weight-adjusted dose, even if milk-plasma ratio were overestimated. Simulation led to similar estimates. Discussion Risk for significant infant exposure to nifurtimox through breast milk seems small and below the level of exposure of infants with Chagas disease receiving nifurtimox treatment. This potential degree of exposure may not justify discontinuation of breast feeding.