1000 resultados para ddc: D2624
Resumo:
For derived flood frequency analysis based on hydrological modelling long continuous precipitation time series with high temporal resolution are needed. Often, the observation network with recording rainfall gauges is poor, especially regarding the limited length of the available rainfall time series. Stochastic precipitation synthesis is a good alternative either to extend or to regionalise rainfall series to provide adequate input for long-term rainfall-runoff modelling with subsequent estimation of design floods. Here, a new two step procedure for stochastic synthesis of continuous hourly space-time rainfall is proposed and tested for the extension of short observed precipitation time series. First, a single-site alternating renewal model is presented to simulate independent hourly precipitation time series for several locations. The alternating renewal model describes wet spell durations, dry spell durations and wet spell intensities using univariate frequency distributions separately for two seasons. The dependence between wet spell intensity and duration is accounted for by 2-copulas. For disaggregation of the wet spells into hourly intensities a predefined profile is used. In the second step a multi-site resampling procedure is applied on the synthetic point rainfall event series to reproduce the spatial dependence structure of rainfall. Resampling is carried out successively on all synthetic event series using simulated annealing with an objective function considering three bivariate spatial rainfall characteristics. In a case study synthetic precipitation is generated for some locations with short observation records in two mesoscale catchments of the Bode river basin located in northern Germany. The synthetic rainfall data are then applied for derived flood frequency analysis using the hydrological model HEC-HMS. The results show good performance in reproducing average and extreme rainfall characteristics as well as in reproducing observed flood frequencies. The presented model has the potential to be used for ungauged locations through regionalisation of the model parameters.
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Nachdem für das Schulfach Musik mit dem Kompetenzmodell „Musik wahrnehmen und kontextualisieren" ein erstes empirisch validiertes Kompetenzmodell vorliegt (Jordan et al., 2012), soll mit dieser Studie in Form eines theoriebasierten Modells musikpraktischer Kompetenz der erste Schritt zur empirischen Modellierung eines weiteren Bereichs, nämlich des musikpraktischen, vorgenommen werden. (DIPF/Orig.)
Resumo:
Background: Non-small cell lung cancer (NSCLC) imposes a substantial burden on patients, health care systems and society due to increasing incidence and poor survival rates. In recent years, advances in the treatment of metastatic NSCLC have resulted from the introduction of targeted therapies. However, the application of these new agents increases treatment costs considerably. The objective of this article is to review the economic evidence of targeted therapies in metastatic NSCLC. Methods: A systematic literature review was conducted to identify cost-effectiveness (CE) as well as cost-utility studies. Medline, Embase, SciSearch, Cochrane, and 9 other databases were searched from 2000 through April 2013 (including update) for full-text publications. The quality of the studies was assessed via the validated Quality of Health Economic Studies (QHES) instrument. Results: Nineteen studies (including update) involving the MoAb bevacizumab and the Tyrosine-kinase inhibitors erlotinib and gefitinib met all inclusion criteria. The majority of studies analyzed the CE of first-line maintenance and second-line treatment with erlotinib. Five studies dealt with bevacizumab in first-line regimes. Gefitinib and pharmacogenomic profiling were each covered by only two studies. Furthermore, the available evidence was of only fair quality. Conclusion: First-line maintenance treatment with erlotinib compared to Best Supportive Care (BSC) can be considered cost-effective. In comparison to docetaxel, erlotinib is likely to be cost-effective in subsequent treatment regimens as well. The insights for bevacizumab are miscellaneous. There are findings that gefitinib is cost-effective in first- and second-line treatment, however, based on only two studies. The role of pharmacogenomic testing needs to be evaluated. Therefore, future research should improve the available evidence and consider pharmacogenomic profiling as specified by the European Medicines Agency. Upcoming agents like crizotinib and afatinib need to be analyzed as well. © Lange et al.
Resumo:
[Der Beitrag nähert sich der Frage], ob die aktuelle JeKi-Praxis günstige Voraussetzungen für die erweiterte Einführung inklusiver Settings bietet und wie die bestehenden Ansätze eines inklusiven JeKi-Unterrichts in Grundschulen mit gemeinsamem Unterricht eingeschätzt werden können. [...] Für jede dieser Ebenen wurden in der Studie „JeKi und gemeinsamer Unterricht" ausgewählte Fragestellungen untersucht, in der vorliegenden Darstellung sollen zwei Aspekte im Vordergrund stehen, die der innerpsychischen und der institutionellen Ebene zugeordnet werden können. (DIPF/Orig.)
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Ethernet connections, which are widely used in many computer networks, can suffer from electromagnetic interference. Typically, a degradation of the data transmission rate can be perceived as electromagnetic disturbances lead to corruption of data frames on the network media. In this paper a software-based measuring method is presented, which allows a direct assessment of the effects on the link layer. The results can directly be linked to the physical interaction without the influence of software related effects on higher protocol layers. This gives a simple tool for a quantitative analysis of the disturbance of an Ethernet connection based on time domain data. An example is shown, how the data can be used for further investigation of mechanisms and detection of intentional electromagnetic attacks. © 2015 Author(s).
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We compute how bulk loops renormalize both bulk and brane effective interactions for codimension-two branes in 6D gauged chiral supergravity, as functions of the brane tension and brane-localized flux. We do so by explicitly integrating out hyper- and gauge-multiplets in 6D gauged chiral supergravity compactified to 4D on a flux-stabilized 2D rugby-ball geometry, specializing the results of a companion paper, arXiv:1210.3753 , to the supersymmetric case. While the brane back-reaction generically breaks supersymmetry, we show that the bulk supersymmetry can be preserved if the amount of brane- localized flux is related in a specific BPS-like way to the brane tension, and verify that the loop corrections to the brane curvature vanish in this special case. In these systems it is the brane-bulk couplings that fix the size of the extra dimensions, and we show that in some circumstances the bulk geometry dynamically adjusts to ensure the supersymmetric BPS-like condition is automatically satisfied. We investigate the robustness of this residual supersymmetry to loops of non-supersymmetric matter on the branes, and show that supersymmetry- breaking effects can enter only through effective brane-bulk interactions involving at least two derivatives. We comment on the relevance of this calculation to proposed applications of codimension-two 6D models to solutions of the hierarchy and cosmological constant problems. © 2013 SISSA.
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Storytelling as a teaching method in the music classroom can no longer be found in repertoires of music teaching methods, even though stories are still being told in music lessons nowadays and storytelling has a long teaching tradition. Numerous sources of the late 18th century and beyond account for different kinds of storytelling in the German music classroom. They have systematically been analysed with regard to certain aspects and teaching patterns. In this way the present study takes account of a decades- old demand within the discipline of historical music pedagogical research, which has postulated a structural historiography. Starting with a reflection of the historiographical research method the author finally illustrates the benefits of combining historical classroom research and the research of current teaching practices. (DIPF/Orig.)
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This paper deals with the development of an advanced parametrical modelling concept for packaging components of a 24 GHz radar sensor IC used in automotive driver assistance systems. For fast and efficient design of packages for system-in-package modules (SiP), a simplified model for the description of parasitic electromagnetic effects within the package is desirable, as 3-D field computation becomes inefficient due to the high density of conductive elements of the various signal paths in the package. By using lumped element models for the characterization of the conductive components, a fast indication of the design's signal-quality can be gained, but so far does not offer enough flexibility to cover the whole range of geometric arrangements of signal paths in a contemporary package. This work pursues to meet the challenge of developing a flexible and fast package modelling concept by defining parametric lumped-element models for all basic signal path components, e.g. bond wires, vias, strip lines, bumps and balls. © Author(s) 2011. CC Attribution 3.0 License.
Resumo:
Teaching music theory is an essential, yet a barely researched part of music education in secondary schools. This paper examines the expert knowledge of Bavarian teachers regarding this subject After discussing the background and the methodology of this study the differences among the music teachers' understanding of "music theory" are illustrated with three examples: While all three interviewees agree that music theory is a set of specific knowledge, they differ by a) locating it in the non-practical, b) connecting it with practical applications or c) isolating it as knowledge, that, at first, has to be learned in isolation. These conceptions of music theory can be understood as intrinsically connected with didactic assumptions and are founded in the teachers' biographies. (DIPF/Orig.)
Resumo:
Background: Calluna vulgaris is one of the most important landscaping plants produced in Germany. Its enormous economic success is due to the prolonged flower attractiveness of mutants in flower morphology, the so-called bud-bloomers. In this study, we present the first genetic linkage map of C. vulgaris in which we mapped a locus of the economically highly desired trait " flower type" .Results: The map was constructed in JoinMap 4.1. using 535 AFLP markers from a single mapping population. A large fraction (40%) of markers showed distorted segregation. To test the effect of segregation distortion on linkage estimation, these markers were sorted regarding their segregation ratio and added in groups to the data set. The plausibility of group formation was evaluated by comparison of the " two-way pseudo-testcross" and the " integrated" mapping approach. Furthermore, regression mapping was compared to the multipoint-likelihood algorithm. The majority of maps constructed by different combinations of these methods consisted of eight linkage groups corresponding to the chromosome number of C. vulgaris.Conclusions: All maps confirmed the independent inheritance of the most important horticultural traits " flower type" , " flower colour" , and " leaf colour". An AFLP marker for the most important breeding target " flower type" was identified. The presented genetic map of C. vulgaris can now serve as a basis for further molecular marker selection and map-based cloning of the candidate gene encoding the unique flower architecture of C. vulgaris bud-bloomers. © 2013 Behrend et al.; licensee BioMed Central Ltd.
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With over 30 years of tradition, breaking in Germany provides fascinating insights into the learning of dance in Hip Hop culture, reaching from informal street learning to the introduction of courses in educational institutions. This article draws information from a qualitative empirical study based on the Grounded Theory Methodology. The study asked subjects ranging from first-generation German B-Boys and B-Girls to teenage students about how they have learned and currently learn to break. The interview material reveals a rich and self-regulated learning culture with strong impact on protagonists. A synergy of social, aesthetic, and ethical principles seems to be characteristic, creating a gravitational field of learning with a unique and complex form of imitation at its core. (DIPF/Orig.)
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In this contribution, a system identification procedure of a two-input Wiener model suitable for the analysis of the disturbance behavior of integrated nonlinear circuits is presented. The identified block model is comprised of two linear dynamic and one static nonlinear block, which are determined using an parameterized approach. In order to characterize the linear blocks, an correlation analysis using a white noise input in combination with a model reduction scheme is adopted. After having characterized the linear blocks, from the output spectrum under single tone excitation at each input a linear set of equations will be set up, whose solution gives the coefficients of the nonlinear block. By this data based black box approach, the distortion behavior of a nonlinear circuit under the influence of an interfering signal at an arbitrary input port can be determined. Such an interfering signal can be, for example, an electromagnetic interference signal which conductively couples into the port of consideration. © 2011 Author(s).
Resumo:
Instrumental or vocal teaching in music schools and general music education in compulsory schools represents primary elements of German music education. Both directions are combined on a professional basis by string, wind, singing or band classes. Music pedagogical theories describing instrumental teaching and school music, respectively, have evolved differently in the past - a fact that is scarcely addressed in the literature. In this article both problem-centered interview and video-assisted thought- reconstruction techniques are employed to use differences in the corresponding theories for building empirically grounded explanations of string classes. Major findings indicate that the instrumental teacher's background in traditional teaching structures strongly influences the realization of certain characteristics of aesthetic practice. (DIPF/Orig.)
Resumo:
Presenting acoustic information has become increasingly interesting for technique training and control in various sports. In elite rowing, acoustic feedback is a new and promising application to optimize the boat's forward motion. This paper describes the potential of acoustic information which represents the movement-relevant information on the boat's forward motion for rowing and its implementation as online acoustic feedback during on-water training sessions. The first significant results were encouraging and support the intention to implement the acoustic information regularly into training processes for elite athletes. © Faculty of Education. University of Alicante.
Resumo:
This article deals with a pedagogical concept called "Verständige Musikpraxis". It wants to elicit whether and if how its effects might be empirically relevant. Starting point is an analysis of a suite of 4 videotaped music lessons with an emphasis on singing in the classroom in primary schools. The taped lessons show a similarity in structure: a phase of practising is mostly followed by a phase of practical learning and reflection, which in turn is interrupting the process. In the phenomenological theory of learning this moment of irritation is a hallmark of the learning process per se. (DIPF/Orig.)