Bilateral Sequential NAION: A Comparison of Visual Outcomes in Fellow Eyes Using Quantitative Analysis of Goldmann Visual Fields

Purpose: Previous studies of the visual outcome in bilateral non-arteritic anterior ischemic optic neuropathy (NAION) have yielded conflicting results, specifically regarding congruity between fellow eyes. Prior studies have used measures of acuity and computerized perimetry but none has compared Goldmann visual field outcomes between fellow eyes. In order to better define the concordance of visual loss in this condition, we reviewed our cases of bilateral sequential NAION, including measures of visual acuity, pupillary function and both pattern and severity of visual field loss.Methods: We performed a retrospective chart review of 102 patients with a diagnosis of bilateral sequential NAION. Of the 102 patients, 86 were included in the study for analysis of final visual outcome between the affected eyes. Visual function was assessed using visual acuity, Goldmann visual fields, color vision and RAPD. A quantitative total visual field score and score per quadrant was analyzed for each eye using the numerical Goldmann visual field scoring method previously described by Esterman and colleagues. Based upon these scores, we calculated the total deviation and pattern deviation between fellow eyes and between eyes of different patients. Statistical significance was determined using nonparametric tests.Results: A statistically significant correlation was found between fellow eyes for multiple parameters, including logMAR visual acuity (P = 0.0101), global visual field (P = 0.0001), superior visual field (P = 0.0001), and inferior visual field (P = 0.0001). In addition, the mean deviation of both total (P = 0.0000000007) and pattern (P = 0.000000004) deviation analyses was significantly less between fellow eyes ("intra"-eyes) than between eyes of different patients ("inter"-eyes).Conclusions: Visual function between fellow eyes showed a fair to moderate correlation that was statistically significant. The pattern of vision loss was also more similar in fellow eyes than between eyes of different patients. These results may help allow better prediction of visual outcome for the second eye in patients with NAION. These findings may also be useful for evaluating efficacy of therapeutic interventions.

Report on a special investigation of the Southwest Iowa Transit Agency for the period July 1, 2011 through June 30, 2012

Report on a special investigation of the Southwest Iowa Transit Agency for the period July 1, 2011 through June 30, 2012

Report on a special investigation of the City of Buffalo for the period September 25, 2008 through September 30, 2010

Report on a special investigation of the City of Buffalo for the period September 25, 2008 through September 30, 2010

Special plates report

This report is submitted by the Iowa Department of Transportation, Motor Vehicle Division in compliance with Administrative Rule 761-401.18(3) Discontinuance. This rule requires the department to report to the legislature if 250 paid applications for any of the special registration plates subject to this rule are not submitted within one year after the date the department makes the plate available for application in order to request authority to discontinue any of the special registration plates established under Iowa Code section 321.34, new subsections 20C, 25 and 26 as amended by 2011 Iowa Acts, House File 651, section 2.

Report on a special investigation of the Adair County Engineer’s Office for the period December 5, 2001 through December 31, 2011

Report on a special investigation of the Adair County Engineer’s Office for the period December 5, 2001 through December 31, 2011

Report on a special investigation of the City of Masonville for the period of March 18, 2002 to November 30, 2011

Report on a special investigation of the City of Masonville for the period of March 18, 2002 to November 30, 2011

Report on a special investigation of the Coggon Municipal Light Plant for the period July 1, 2004 through August 27, 2012

Report on a special investigation of the Coggon Municipal Light Plant for the period July 1, 2004 through August 27, 2012

Report on a special investigation of the City of Stockport for the period July 1, 2007 through October 31, 2011

Report on a special investigation of the City of Stockport for the period July 1, 2007 through October 31, 2011

Report on a special investigation of the City of Muscatine for the period July 1, 2008 through March 8, 2012

Report on a special investigation of the City of Muscatine for the period July 1, 2008 through March 8, 2012

Special investigation of the Iowa Department of Transportation for the period January 29, 1994 through July 7, 2011

Special investigation of the Iowa Department of Transportation for the period January 29, 1994 through July 7, 2011

Special investigation of the University of Northern Iowa Events Complex Concessions for the period October 1, 2006 through March 31, 2012

Special investigation of the University of Northern Iowa Events Complex Concessions for the period October 1, 2006 through March 31, 2012

Report on a special investigation of the City of Indianola for the period June 1, 2006 through August 31, 2012

Report on a special investigation of the City of Indianola for the period June 1, 2006 through August 31, 2012

Report on a special investigation of the Lyon County Engineer’s Office for the period August 1, 2006 through May 31, 2012

Report on a special investigation of the Lyon County Engineer’s Office for the period August 1, 2006 through May 31, 2012

Report on a special investigation of the Creston Water Works for the period July 1, 2005 through November 16, 2012

Report on a special investigation of the Creston Water Works for the period July 1, 2005 through November 16, 2012