Ecological fallacy in a time series context: evidence from the Spanish regional unemployment rates

The ecological fallacy (EF) is a common problem regional scientists have to deal with when using aggregated data in their analyses. Although there is a wide number of studies considering different aspects of this problem, little attention has been paid to the potential negative effects of the EF in a time series context. Using Spanish regional unemployment data, this paper shows that EF effects are not only observed at the cross-section level, but also in a time series framework. The empirical evidence obtained shows that analytical regional configurations are the least susceptible to time effects relative to both normative and random regional configurations, while normative configurations are an improvement over random ones.

The natural hallucinogen 5-MeO-DMT, component of Ayahuasca, disrupts cortical function in rats: reversal by antipsychotic drugs

5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a natural hallucinogen component of Ayahuasca, an Amazonian beverage traditionally used for ritual, religious and healing purposes that is being increasingly used for recreational purposes in US and Europe. 5MeO-DMT is of potential interest for schizophrenia research owing to its hallucinogenic properties. Two other psychotomimetic agents, phencyclidine and 2,5-dimethoxy-4-iodo-phenylisopropylamine (DOI), markedly disrupt neuronal activity and reduce the power of low frequency cortical oscillations (<4 Hz, LFCO) in rodent medial prefrontal cortex (mPFC). Here we examined the effect of 5-MeO-DMT on cortical function and its potential reversal by antipsychotic drugs. Moreover, regional brain activity was assessed by blood-oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). 5-MeO-DMT disrupted mPFC activity, increasing and decreasing the discharge of 51 and 35% of the recorded pyramidal neurons, and reducing (−31%) the power of LFCO. The latter effect depended on 5-HT1A and 5-HT2A receptor activation and was reversed by haloperidol, clozapine, risperidone, and the mGlu2/3 agonist LY379268. Likewise, 5-MeO-DMT decreased BOLD responses in visual cortex (V1) and mPFC. The disruption of cortical activity induced by 5-MeO-DMT resembles that produced by phencyclidine and DOI. This, together with the reversal by antipsychotic drugs, suggests that the observed cortical alterations are related to the psychotomimetic action of 5-MeO-DMT. Overall, the present model may help to understand the neurobiological basis of hallucinations and to identify new targets in antipsychotic drug development.

La premsa comarcal i el consum de noves pantalles

La investigació es centra en la visió dels mitjans de proximitat i el consum de d’aquests mitjans en el marc de la convergència digital a Catalunya. No és cap misteri l’aparició de nous hàbits de consum de continguts dels mitjans de comunicació nous i vells, on uns prefereixen, la premsa, la televisió i la ràdio, i d’altres amplien l’experiència i/o prefereixen la consulta de portals web, xarxes socials o continguts per internet a través de, dispositius mòbils, consoles de vídeojocs, etc. La recerca esta està dividida en dos grans blocs: per una banda, un estudi qualitatiu amb entrevistes en profunditat als responsables de mitjans comarcals sobre la seva visió com mitjà, i la seva trajectòria, i sobre els propis lectors, radiooients, i seguidors, ; i per l’altra banda, un quantitatiu mitjançant a partir d’una enquesta online a residents a Catalunya sobre el consum de mitjans. Les conclusions mostren una radiografia de l’actual ecosistema mediàtic a Catalunya.

Stratification of regional sampling by model-predicted changes of carbon stocks in Forested mineral soils

Selective papers of the workshop on "Development of models and forest soil surveys for monitoring of soil carbon", Koli, Finland, April 5-9 2006.

Regional potential for collaborative implementation of small CHP plants in bioenergy technology

This thesis is a preliminary study targeting South-Eastern Finland. The objective was to find out the financial and functional readiness and willingness of the small and medium-sized enterprises of the region to manufacture and sell distributed bioenergy solutions collaboratively as a business network. In this case these solutions mean small-scale (0.5 - 3 MW) woodchips-operated combined heat and power (CHP) plants. South-Eastern Finland has suffered from a decline in the recent years, mostly due to the problems of the traditionally strong industrial know-how area of the region, the paper industry. Local small and medium-sized companies will have to find new ways to survive the toughening competition. A group of 40 companies from suitable industries were selected and financial and comparative analysis was performed on them. Additionally 19 managing directors of the companies were selected for an interview to find out their views on networking, its requirements, advantages and the general interest in it. The studied companies were found to be generally in fairly good financial condition and in that sense, fit for networking activities. The interviews revealed that the companies were capable of producing all the needed elements for the plants in question, and the managers appeared to be very interested in and have a positive attitude towards such business networks. Thus it can be said that the small and medium-sized companies of the region are capable of and interested in manufacturing small bio-CHP plants as a production network.

On the development of object functions and restrictions for shapes made with a turret punch press

This study presents the information required to describe the machine and device resources in the turret punch press environment which are needed for the development of the analysing method for automated production. The description of product and device resources and their interconnectedness is the starting point for method comparison the development of expenses, production planning and the performance of optimisation. The manufacturing method cannot be optimized unless the variables and their interdependence are known. Sheet metal parts in particular may then become remarkably complex, and their automatic manufacture may be difficult or, with some automatic equipment, even impossible if not know manufacturing properties. This thesis consists of three main elements, which constitute the triangulation. In the first phase of triangulation, the manufacture occuring on a turret punch press is examined in order to find the factors that affect the efficiency of production. In the second phase of triangulation, the manufacturability of products on turret punch presses is examined through a set of laboratory tests. The third phase oftriangulation involves an examination of five industry parts. The main key findings of this study are: all possible efficiency in high automation level machining cannot be achieved unless the raw materials used in production and the dependencies of the machine and tools are well known. Machine-specific manufacturability factors for turret punch presses were not taken into account in the industrial case samples. On the grounds of the performed tests and industrial case samples, the designer of a sheet metal product can directly influence the machining time, material loss, energy consumption and the number of tools required on a turret punch press by making decisions in the way presented in the hypothesis of thisstudy. The sheet metal parts to be produced can be optimised to bemanufactured on a turret punch press when the material to be used and the kinds of machine and tool options available are known. This provides in-depth knowledge of the machine and tool properties machine and tool-specifically. None of the optimisation starting points described here is a separate entity; instead, they are all connected to each other.