984 resultados para Host Community
Resumo:
This report details the efforts of the community action network in Iowa.
Resumo:
This report details the efforts of the community action network in Iowa.
Resumo:
This report details the efforts of the community action network in Iowa.
Resumo:
This report details the efforts of the community action network in Iowa.
Resumo:
It is well established that T cell-deficient nude and SCID mice can be reconstituted by i.v. injection of small numbers of purified peripheral CD4+ T cells; however, the requirements for expansion of the transferred T cells in such systems are not clear. We show here that blood and lymphoid organs of MHC class II-deficient mice (which selectively lack mature CD4+ T cells) cannot be reconstituted by transfer of purified splenic CD4+ T cells, whereas TCRalpha-deficient mice (which lack both CD4+ and CD8+ mature T cells) are readily reconstituted. The failure of CD4+ T cell reconstitution in MHC class II-deficient mice was not due to the presence of CD8+ T cells, since similar results were obtained in TCRalpha-MHC class II double-deficient mice. Consistent with most previous studies CD4+ T cells in reconstituted TCRalpha-deficient mice had a diverse TCR Vbeta repertoire and were predominantly of an activated/memory (CD44high) phenotype. Collectively our data demonstrate that the expansion of peripheral CD4+ T cells in a T cell-deficient host is dependent upon interactions of the TCR with MHC class II.
Resumo:
Community School District Audit Report
Resumo:
Monthly newsletter for the Iowa Department of Public Health
Resumo:
Monthly newsletter for the Iowa Department of Public Health