Iowa Aviation Bulletin, Spring 2002

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Winter 2001-2002

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Fall 2001

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Summer 2001

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Spring 2001

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Winter 2001

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Fall 2000

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Summer 2000

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Spring 2000

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Fall 1999

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Iowa Aviation Bulletin, Summer 1999

Quarterly newsletter published by the Iowa Department of Transportation's Office of Aviation that contains information of interest to aviation-related persons and organizations.

Bathonian radiolarians from an ophiolitic melange of the Alpine Tethys (Gets Nappe, Swiss-French Alps)

The determination of radiolarite ages of supraophiolitic rocks date the expansion age of oceanic crust. Radiolarites from the Gets nappe, a decollement cover nappe, provide the means of dating selected localities of outcropping oceanic crust based on their radiolarian faunas. Some studied samples from the ophiolitic melange (Perri re series) have a very well preserved and highly diverse radiolarian fauna of biochronological significance. The age of the radiolarites is established by correlation with the biozonation of Baumgartner et al. (1995b), which indicates a Bathonian age for the oldest radiolarian assemblages. Accordingly, these radiolarites represent remains of the oldest sediments recorded after the opening of the Piemont-Ligurian Ocean. This age is in agreement with those recently established by isotopic methods (166 +/- 1 Ma U-Pb and 165.9 +/- 2.2 Ma Ar-40/Ar-39) in the associated gabbros from the ophiolitic melange. The isotopic age and paleontological results are important because they represent the oldest dating of the oceanic crust of the Piemont-Ligurian Ocean, proving a Late Bajocian-Early Bathonian age for the oceanization in the western Tethys. The systematic part presents a complete Bathonian radiolarian assemblage from two of the best preserved samples; the illustrated assemblage contains 180 species attributed to 66 genera (44 nassellarians, 22 spumellarians and 1 entactinarian). Twenty new species and three new genera (Helvetocapsa, Plicaforacapsa and Theocapsomella) are formally described.

Department of Human Rights Division of Persons with Disabilities Annual Performance Plan Report, September 2005

This report is published in accordance with the Accountable Government Act to improve decision-making and increase accountability to stakeholders and citizens. This report contains performance information regarding our primary programs including, the Youth Leadership Forum, the College Leadership Forum, the State Access Grant and the Client Assistance Program. Major accomplishments this year include continuation of our core programs, a key role in the Iowa Great Places initiative and providing Cultural Competency training to governmental and non-governmental agencies.

The Americans with Disabilities Act Employer/Employee Rights & Responsibilities, May 2001

This publication was designed with the belief that the ADA addresses both employers and employees to achieve a viable workforce and productive society. The law was intended to reflect the balance between the employer and the employee with a disability. This booklet contains information on Title I of the ADA but should not be considered legal advice. Title I is directly related to the employment provisions of the law. Both employers and employees have responsibilities and rights under the ADA and this booklet addresses the balance of rights and responsibilities under the law. This law was designed to remove the barriers that prevent qualified persons from enjoying equal employment opportunities solely because of a disability. It demonstrates America recognizing the vitality and abilities of all people to contribute in our society, particularly in the area of employment. This is civil rights law. It prohibits discrimination against persons with disabilities and encourages the recognition of citizens with disabilities as full participants in American life. It recognizes that these members of the American work force are an excellent resource for employers.

Interaction of GAG trinucleotide repeat and C-129T polymorphisms impairs expression of the glutamate-cysteine ligase catalytic subunit gene.

Glutamate cysteine ligase (GCL) catalyzes the rate-limiting step in the de novo synthesis of glutathione (GSH). The catalytic subunit (GCLC) of GCL contains a GAG trinucleotide-repeat (TNR) polymorphism within the 5'-untranslated region (5'-UTR) that has been associated with various human disorders. Although several studies suggest that this variation influences GSH content, its implication for GCLC expression remains unknown. To better characterize its functional significance, we performed reporter gene assays with constructs containing the complete GCLC 5'-UTR upstream of a luciferase gene. Transfection of these vectors into various human cell lines did not reveal any significant differences between 7, 8, 9, or 10 GAG repeats, under either basal or oxidative stress conditions. To correlate these results with the previously described down-regulation induced by the C-129T GCLC promoter polymorphism, combinations of both variations were tested. Interestingly, the -129T allele down-regulates gene expression when combined with 7 GAG but not with 8, 9, or 10 GAG TNRs. This observation was confirmed in primary fibroblast cells, in which the combination of GAG TNR 7/7 and -129C/T genotypes decreased the GCLC protein level. These results provide evidence that interaction of the two variations can efficiently impair GCLC expression and thus suggest its involvement in the pathogenesis of diseases related to GSH metabolism.