992 resultados para Comunicação celular


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Pós-graduação em Ciência da Informação - FFC

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Pós-graduação em Comunicação - FAAC

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Pós-graduação em Engenharia Elétrica - FEIS

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The main feature of pulmonary emphysema is airflow obstruction resulting from the destruction of the alveolar walls distal to the terminal bronchioles. Existing clinical approaches have improved and extended the quality of life of emphysema patients. However, no treatment currently exists that can change the disease course and cure the patient. The different therapeutic approaches that are available aim to increase survival and/or enhance the quality of life of emphysema patients. In this context, cell therapy is a promising therapeutic approach with great potential for degenerative pulmonary diseases. In this protocol proposition, all patients will be submitted to laboratory tests, such as evaluation of heart and lung function and routine examinations. Stem cells will be harvested by means of 10 punctures on each anterior iliac crest, collecting a total volume of 200 mL bone marrow. After preparation, separation, counting and labeling (optional) of the mononuclear cells, the patients will receive an intravenous infusion from the pool of Bone Marrow Mononuclear Cells (BMMC). This article proposes a rational and safe clinical cellular therapy protocol which has the potential for developing new projects and can serve as a methodological reference for formulating clinical application protocols related to the use of cellular therapy in COPD. This study protocol was submitted and approved by the Brazilian National Committee of Ethics in Research (CONEP - Brazil) registration number 14764. It is also registered in ClinicalTrials.gov (NCT01110252). (c) 2013 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S.L. All rights reserved.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The oral cancer model in hamsters shows many simílarities with developmental oral cancer in humans. The proliferating capacity is one the most characteristics of neoplásica ce/Is and detection of these ce/Is allow us, throughout of its counting, to achieve an estimated tumour growing index, with a consequent repercussion about prognostic and in the treatment of those lesions. 40 golden Syrian hamsters, both genders, aged between two to six mouth and weight 150g in average were used. The left síde of tangue of each animal was painted for eight consecutive weeks, with a solution of DMBA. Tongues were removed, fixed in 10% buffered fonnal solution. The histological slides were stained by AgNOR technique and by PCNA and β-catenin immunohistochemical antibodies. Statistical analyzes were performed by ANOVA one-way test and Tukey test. We may conclude that an association between AgNOR and PCNA might indicate the higher proliferating activity of the analyzed celIs. The experimental carcinogenesis model in hamster tongue is an available methodology for immunohistochemistry study. And finally, PCNA and β-catenin immunohistochemical antibodies may be used to analyze possible premalignant areas in oral leukoplakia

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Introduction: Individuals born from the 1990’s to accompany technological change course and learn how to use the technological resources that have access before they even learn to read or write. In this sense, the literature considers the digital natives or even 'Google generation'. However, it has been questioned their skills to identify information needs and seeking and use of information in the most varied environments digital information available on the Web. Objectives: To characterize the behavior of information seeking in everyday life of a group of teenage students from a private school in Marilia, Sao Paulo. Methodology: A qualitative study with 30 adolescent students of a private school in Marilia, Sao Paulo. Data collection was accomplished at first by means of a questionnaire, based on the research of Hughes-Hussell and August (2007), containing questions about age, gender, hobbies and everyday tasks, and issues the use of computers and the internet, which allowed determination of the social, economic and cultural rights of respondents. Results: have focused on the use of Information and Communication Technologies (ICT) to search access and use information. It was suggested that the "Brotherhood of Informatics', an incentive for students to (re) learn the tools of digital communication and make appropriate use of the resources, products and services on the web to search and effective use of information compatible with their needs and that is tied to the ethical and responsible use of technology environments. Conclusions: The results arising from this study will continue through the continuation of the Confraternity of Computing, which became a "thermometer" on the use of digital information environments and the attitude of the students in front of Information and Communication Technologies in the College “Cristo Rei”.

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Introduction: Innovation and its processes, especially in the field of technology, are a focus of Information Science as a science of Human, as they determine the establishment of new habits, relevant socio-cultural indicators to understanding the history of cultures. Objective: This article reflects on the problematic: whether and how Information and Communication Technologies have impacted the lives of digital natives, whether the average individual is prepared to conscientiously experience the technological environment, how the current system can prepare future generations of professionals, and how the adults who grew up in the twentieth century, in an analogue society can prepare young people for a twenty-first century digital reality, widely different from theirs. Methodology: This paper was based on Literature Review. Results: As the sophistication of technology advances, society has to continually review the way it appropriates information to adjust to these changes. Conclusions: As for relevance of the methodologies that lead to innovative disruptive actions in hybrid realities such as the Brazilian one, with niches of poverty and prosperity, it is believed that it is in poor countries or countries with significant social differences such as Brazil where the need for a change of socio technocultural paradigm and innovative action urge to take place.

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Introduction: This paper presents preliminary results of the research project "Information access: actions and strategies of the Chamber of Deputies to meet 12.527/2011 Law”. Finally some considerations about the implementation of the Law within the Chamber of Deputies are presented. Objectives: Discuss the matter of public information access after the new Brazilian information access law and his relationship between the theories information policy, information regime and informational state. Methodology: Bibliographic research about several theoretical topics related to information access were raised, for example: the concept of information, information policy, informational state, information regime, electronic government and information asymmetry. Results: The preliminaries data shows a convergence of information policies from many countries, for example, Finland, Canada and South Africa, to a same point, which indicates an increase of transparency and a bigger active disclosure of information public. Conclusion: In Brazilian case, in the relationship between State and citizen, the new information access law means a materialization paradigm change or the concretization de other information regime. The sanction of this law can be interpreted as another step to increase the transparency and the affirmation of democratic relationship between State and society.

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Augmentative and Alternative Communication Resources have proven to be helpful in the insertion of students with disabilities and complex communication needs into a variety of pedagogical activities and expand the skills and competencies of the teacher in the teaching-learning. The objective of this research was to identify the perception of teachers regarding the use of augmentative and alternative communication during an intervention program in Preschool. Participants were a special class of Preschool students with disabilities and severe communication complexity, along with their teacher and the researcher. For the development of this research, a Alternative Communication Program was applied. The teacher was provided with systematic guidance concerning language and communication. In a collaborative process, three children’s songs were selected according to the teacher’s pedagogical planning and adapted resources through Augmentative and Alternative Communication Systems. During the intervention program, assisted evaluations also took place immediately after the activities with the music. The data were collected in audio recordings. For data analysis, content analysis was carried out resulting in the outlining of themes and subthemes. Results indicated that the teacher identified that Augmentative and Alternative Communication Systems can to facilitate expression abilities of students with disabilities; that Augmentative and Alternative Communication Systems can be used by children in Preschool; and that resources adapted through augmentative and alternative communication systems should be in accordance with the specificities of students.

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This study aimed to enter a training program for family members of children, youth and adults who use augmentative and alternative communication systems in the context of alternative languages . The study included families in the age group of 25-65 years in the period 2010- 2012. The activities were held weekly with duration of one hour in a alternative communication laboratory. All activities were videotaped and after that, the verbal participants’ reports were transcribed. The obtained categories were analyzed according to the steps of the program. The results indicated that families realized: the necessity of graphics systems for communication; the importance of adapted materials; and the need to understand their children’s different skills. The study reinforced the need for systematic and continuous guidance for families, as well as highlighted the use of graphics systems in the context of language.

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In the organizational context culture and communication are fundamental to the processes of appropriation, sharing, generation and use of knowledge. However, in organizations, it is evident that there is little awareness about the influence of information culture and informational communication in the scope of knowledge management. In this perspective and considering the theoretical context, we analyze the influence of culture and communication in the construction of knowledge in an organizational context. This study presents a qualitative research covering national literature focusing theoretical literature published about this thematic. Analyzing this literature we have verified that without an appropriate information culture and an appropriate information communication favoring the organizational processes, hardly the managers would reach the purpose of stimulating knowledge creation within the organization's environment. In conclusion we consider that culture and communication are the foundations for the effectiveness of activities that occur within the context of knowledge management.