W kraju tysiaca jezior: (z podró·zy i przechadzek po Finlandyi)

Lisäpainokset: 2. p. 1897.

Effect of iodide on Fas, Fas-ligand and Bcl-w mRNA expression in thyroid of NOD mice pretreated with methimazole

Nonobese diabetic (NOD) mice and a derived strain, NOD.H.2h4, have been used as a model for experimental spontaneous thyroiditis and thyroiditis induced by iodide excess after a goiter-inducing period. Some authors have proposed that iodide, given after methimazole or propylthiouracil, is capable of inducing apoptosis in thyroid cells and that anti-thyroid drugs can modulate the expression of apoptosis components such as Fas and its ligand (Fas-L). Here we evaluated the effect of potassium iodide (20 µg/animal for 4 days, ip) given to NOD mice at the 10th week of life after exposure to methimazole (1 mg/ml) in drinking water from the 4th to the 10th week of life. Fas, Fas-L and Bcl-w expression were analyzed semiquantitatively by RT-PCR immediately after potassium iodide administration (group MI44D) or at week 32 (MI32S). Control groups were added at 10 (C10) and 32 weeks (C32), as well as a group that received only methimazole (CM10). An increase in the expression of Fas-L and Bcl-w (P<0.01, ANOVA) was observed in animals of group MI44D, while Fas was expressed at higher levels (P = 0.02) in group C32 (72.89 ± 47.09 arbitrary units) when compared to group C10 (10.8 ± 8.55 arbitrary units). Thus, the analysis of Fas-L and Bcl-w expression in the MI44D group and Fas in group C32 allowed us to detect two different patterns of expression of these apoptosis components in thyroid tissue of NOD mice.

Utkast till en geologisk karta öfver Spetsbergen af A. E. Nordenskiöld : enligt iaktagelser under de svenska expeditionerna 1858, 1861 och 1864 / af C. W. Blomstrand, O. Torell och A. E. Nordenskiöld

Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

Plan af Lowisa stad utgifven 1837 af C. W. Gyldén.

1:8000.

Plan af Wiborg / utgifven 1839 af C. W. Gyldén.

[1:10000].

Plan af Kexholm / utgifven 1843 af C. W. Gyldén.

[1:8000].

Plan af Sordavala / utgifven 1840 af C. W. Gyldén.

[1:8000].

Plan af Willmanstrand / utgifven 1838 af C. W. Gyldén.

[1:4000].

Emil eller om uppfostran. Af J. J. Rousseau medborgare i Geneve. Öfversättning af J. W. Tuderus. Första tomen

Motto: Sanabilibus aegrotamus malis; ... Seneca.

Allvin och Theodor. Läsebok för barn. Från tyskan öfversatt af Joh. Henr. Avellan

Arkit: 6 arkintunnuksetonta lehteä, A-F8 G6.

Use of cereal bars with quinoa (Chenopodium quinoa W.) to reduce risk factors related to cardiovascular diseases

Quinoa is considered a pseudocereal with proteins of high biological value, carbohydrates of low glycemic index, phytosteroids, and omega-3 and 6 fatty acids that bring benefits to the human health. The purpose of this study was to investigate the effects of quinoa on the biochemical and anthropometric profile and blood pressure in humans, parameters for measuring risk of cardiovascular diseases. Twenty-two 18 to 45-year-old students were treated daily for 30 days with quinoa in the form of a cereal bar. Blood samples were collected before and after 30 days of treatment to determine glycemic and biochemical profile of the group. The results indicated that quinoa had beneficial effects on part of the population studied since the levels of total cholesterol, triglycerides, and LDL-c showed reduction. It can be concluded that the use of quinoa in diet can be considered beneficial in the prevention and treatment of risk factors related to cardiovascular diseases that are among the leading causes of death in today's globalized world. However, further studies are needed to prove the benefits observed.

Allvin och Theodor. Läsebok för barn. Från tyskan öfversatt af Joh. Henr. Avellan

Arkit: 6 arkintunnuksetonta lehteä, A-F8 G6.