(Table S1) Age determination of sediment cores of the Gulf of Alaska

Oxygen isotope data from planktonic and benthic foraminifera, on a high-resolution age model (44 14C dates spanning 17,400 years), document deglacial environmental change on the southeast Alaska margin (59°33.32'N, 144°9.21'W, 682 m water depth). Surface freshening (i.e., d18O reduction of 0.8 per mil) began at 16,650 ± 170 cal years B.P. during an interval of ice proximal sedimentation, likely due to freshwater input from melting glaciers. A sharp transition to laminated hemipelagic sediments constrains retreat of regional outlet glaciers onto land circa 14,790 ± 380 cal years B.P. Abrupt warming and/or freshening of the surface ocean (i.e., additional d18O reduction of 0.9 per mil) coincides with the Bølling Interstade of northern Europe and Greenland. Cooling and/or higher salinities returned during the Allerød interval, coincident with the Antarctic Cold Reversal, and continue until 11,740 ± 200 cal years B.P., when onset of warming coincides with the end of the Younger Dryas. An abrupt 1 per mil reduction in benthic d18O at 14,250 ± 290 cal years B.P. likely reflects a decrease in bottom water salinity driven by deep mixing of glacial meltwater, a regional megaflood event, or brine formation associated with sea ice. Two laminated opal-rich intervals record discrete episodes of high productivity during the last deglaciation. These events, precisely dated here at 14,790 ± 380 to 12,990 ± 190 cal years B.P. and 11,160 ± 130 to 10,750 ± 220 cal years B.P., likely correlate to similar features observed elsewhere on the margins of the North Pacific and are coeval with episodes of rapid sea level rise. Remobilization of iron from newly inundated continental shelves may have helped to fuel these episodes of elevated primary productivity and sedimentary anoxia.

The odometer regulation and enforcement process: a systems analysis of the state of Maryland and a proposed study design for a demonstration project. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

Expériences propres a faire connoitre que l'alkali volatil fluor est le remede le plus efficace dans les asphysies : avec des Remarques sur les Effets avantageux qu'il produit dans la morsure de la vipère, dasn la Rage, la Brulure, l'Apoplexie & c /

Mode of access: Internet.

Theologia moralis inter rigorem et laxitatem media : pro ... parochorum, confessariorum ... ex furiori opera theologiae eclecticae excerpta ac tractatu de obligatione ... : et in duos tomos tributa /

Mode of access: Internet.

Morbi deterioris notae, gallorum castra trans Rhenum sita ab anno 1757 ad 1762 infestantes /

Mode of access: Internet.

Evaluation of the Bell 205A-1 turbojet helicopter and spray system for forest application of insecticide /

"GPO 990-424"--P. [4] of cover.

Die Kanzlei Kaiser Konrads II : mit neu bearbeiteten Regesten und drei ungedruckten Urkunden /

Includes documents and quotations in "Anhang": p. 93-163.

The New Testament of our Lord and Saviour Jesus Christ /

"Historic notices of the ante-James vernacular versions of the Scriptures, subsequent to that of Tyndale": p. [85]-98.

Beech-maple region : inventory of natural areas and sites recommended as potential natural landmarks /

Prepared under contract 14-10-9-990-186, Article II as revised 5 April 1970 with the U.S. Dept. of the Interior, National park Service.

NASCIDOS NO SILÊNCIO: AS RELAÇÕES ENTRE FILHOS OUVINTES E PAIS SURDOS NA EDUCAÇÃO

Este trabalho busca apresentar as vivências de três pessoas ouvintes, além do próprio autor, filhas de pais surdos, discutindo as relações familiares entre pais e filhos, mostrando as diferenças em relação às famílias que não possuem pessoas surdas no seu âmago, desmistificando preconceitos e pré-conceitos. Devido as barreiras comunicacionais e pelo preconceito, muitos surdos acabavam sendo privados do direto de serem pais. Nos relatos apresentados nesta dissertação, houve momentos em que isso quase aconteceu na vida dos sujeitos entrevistados para esta pesquisa. Porém, com força e consciência dos direitos adquiridos, esses pais surdos não permitiram que tal coisa acontecesse. O texto inicia com a trajetória formativa e profissional do autor para, em seguida, trazer os autores que abordam temas como surdez (Wrigley, 1996; Lacerda, 1998; Perlin, 1998; Moura, 2000; Sá, 2002; Quadros, 2004; Sacks, 2007), antropologia (Hall, 1992; Gomes, 2008), relações familiares (Lacan, 1987) e autobiografia (Ferraroti, 1991; Pineau, 2006; demartini, 2008). A língua de sinais e a história educacional dos surdos também são discutidas neste trabalho. Por último, são apresentados os relatos de história de vida feitos na pesquisa de campo de forma literária, com as análises dos depoimentos colhidos pelos sujeitos entrevistados (filhos ouvintes e pais surdos) os quais evidenciam que ser filho de pais surdos pode ser tão normal quanto ser filho de pais ouvintes.

The role of the 8-18 helix of CGRP 8-37 in mediating high affinity binding to CGRP receptors; coulombic and steric interactions

1. The role of individual residues in the 8-18 helix of CGRP 8-37 in promoting high-affinity binding to CGRP 1 receptors expressed on rat L6 and human SK-N-MC cells has been examined. The relative potencies of various derivatives were estimated from their ability to inhibit the human αCGRP-mediated increase in cyclic AMP production and the binding of [ 125I]-human αCGRP. 3. Arg 11 and Arg 18 were replaced by serines to give [Ser 11.18]CGRP 8-37. These bound with pKi values <6 to SK-N-MC cells and had apparent pA 2 values of 5.81 ± 0.04 and 5.31 ± 0.11 on SK-N-MC and L6 cells. CGRP 8-37 had a pKi of 8.22 on SK-N-MC cells and pK b values on the above cell lines of 8.95±0.04 and 8.76±0.04. 3. The arginines were replaced with glutamic acid residues. [Glu 11]CGRP 8-37 had a pK b of 7.14±0.14 on SK-N-MC cells (pKi=7.05±0.05) and 6.99±0.08 on L6 cells. [Glu 18]CGRP 8-37 had a pK b of 7.10±0.0.08 on SK-N-MC cells (pKi=6.91±0.23) and 7.12±0.09 on L6 cells. 4. Leu 12, Leu 15 and Leu 16 were replaced by benzoyl-phenylalanine (bpa) residues. On SK-N-MC cells, the apparent pA 2 values of [bpa 12]-, [bpa 15]- and [bpa 16]CGRP 8-37 were respectively 7.43±0.23, 8.34±0.11 and 5.66±0.16 (pKi values of 7.14±0.17, 7.66±0.21 and <6): on L6 cells they were 7.96±0.36, 8.28±0.21 and 6.09±0.04 (all n=3). 5. It is concluded that the Arg 11 and Arg 18 are involved in specific electrostatic interactions with other residues, either on the CGRP 1 receptors or elsewhere on CGRP 8-37. Leu 16 is in a conformationally restricted site when CGRP 8-37 binds to CGRP 1 receptors, unlike Leu 12 and Leu 15.

Performance analysis of DSRC priority mechanism for road safety applications in vehicular networks

Dedicated short range communications (DSRC) has been regarded as one of the most promising technologies to provide robust communications for large scale vehicle networks. It is designed to support both road safety and commercial applications. Road safety applications will require reliable and timely wireless communications. However, as the medium access control (MAC) layer of DSRC is based on the IEEE 802.11 distributed coordination function (DCF), it is well known that the random channel access based MAC cannot provide guaranteed quality of services (QoS). It is very important to understand the quantitative performance of DSRC, in order to make better decisions on its adoption, control, adaptation, and improvement. In this paper, we propose an analytic model to evaluate the DSRC-based inter-vehicle communication. We investigate the impacts of the channel access parameters associated with the different services including arbitration inter-frame space (AIFS) and contention window (CW). Based on the proposed model, we analyze the successful message delivery ratio and channel service delay for broadcast messages. The proposed analytical model can provide a convenient tool to evaluate the inter-vehicle safety applications and analyze the suitability of DSRC for road safety applications.

Mitigation of patterning effects at 40 Gbits/s by skewed channel pre-encoding

Through direct modeling, a reduction of pattern-dependent errors in a standard fiber-based transmission link at 40 Gbits/s rate is demonstrated by application of a skewed data pre-encoding. The trade-off between the improvement of the bit error rate and the loss in the data rate is examined.