Estudo da bula de medicamentos: Uma análise da situação

This study was carried out in the city of Araraquara (SP, Brazil), where 1829 people selected randomly from 42 districts were interviewed with regard to their use of medicines, in particular whether and how they read the insert information sheet and the most frequently read items and problems encountered in the text. Surveys were performed in two stages, the first when package inserts were regulated in Brazil by Portaria SVS 110/1997 (Ministry of Health directive) and the second after the new regulation (RDC 140/2003) came into force. Out of 1829 people interviewed, 1597 reported using some medicine. The markedly similar results in both stages of the research pointed to the difficulties encounteved in reading the package inserts, due to the small letters, the obscure language and the massive amount of information. This paper shows that package inserts of medicines need to be simpler, so the patients have an idea of the importance of the medicine and are able to realize soon any problem that might appear due to the use of the medicine and what action they should take. Furthermore, it will be helpful to the evaluation of the package inserts of medicines, elaborated in conformity with RDC 140, if they work effectively as a source of information and guidance for the patient are not simply given a new layout, while maintaining items that impede their understanding and use.

Qualidade fisiológica de sementes de Sebastiania commersoniana (Baill.) Smith & Downs (branquilho - Euphorbiaceae) durante o armazenamento

This paper aims to evaluate the physiological quality of Sebastiania commersoniana seeds stored in cloth bag, plastic bag and glass container and kept in two conditions: laboratory workbench and cold chamber (4 ± 2°C e 80% relative humidity - RH) for 531 days. Periodically, samples were taken in order to determine the moisture content and to perform germination tests. The experimental design was completely randomized, in factorial scheme of 3 × 2 (wrappings × conditions), for each period of storage evaluated (0, 158, 271, 389 and 531 days of storage). Supplementary, a polynomial regression was adjusted in order to describe the physiological quality of the seeds for the different conditions during the experimental period. The results lead to the following considerations: a) storage under variable temperature and air humidity (laboratory workbench) can be used for periods of over five and a half months, with the seeds stored in cloth bag, plastic bag or glass container; b) the physiological quality of the seeds was not hardly altered when stored in cold chamber in cloth bag, plastic bag and glass container for over 18 months.

Qualidade fisiológica e sanitária de sementes de feijoeiro (Phaseolus vulgaris L.) provenientes do estado de Goiás

The common beans (Phaseolus vulgaris L.) is a fabacea sufficiently spread out in all domestic territory. However, the quality of its seeds represents one of the main causes of low productivity in the beans farmings in Brazil. The objective of this work was to evaluate physiological and sanitary seed qualities of eleven bean cultivars. The physiological seed quality was evaluated trough standard germination and vigor tests. The sanitary seed quality was evaluated through two tests: blotter test was employed to evaluate fungi incidence and Koch & Menten method was employed to observe Sclerotinia sclerotiorum (Lib) de Bary occurrence. Xamego, BRS Valente, Bambu and Pérola had the best results of physiological tests. Jalo Precoce, Roxo 90, Corrente and Aporé had no good results of vigor and germination, besides presenting the lowest indices of died seeds. Fusarium sp., Aspergillus spp., Penicillium sp., Phoma sp., Rhizopus sp. and Botrytis sp. were the fungi detected in the sanity tests.

Physiological maturity of Cnidosculus quercifolius Pax & K. Hoffm. seeds

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Panorama da inserçao internacional da América Latina e Caribe 2009-2010: Crise originada no centro e recuperação impulsionada pelas economias emergentes. Documento informativo

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A relação entre modernização neoliberal e práticas políticas atrasadas no Brasil dos anos 1990

Our goal is to investigate the reasons behind the presence of clientelist-type practices among the popular classes in Brazil, highlighting the decade of the 1990s. Our proposal gives salience to factors regarding the phenomenon's socio-political conjuncture, thereby taking us beyond explanations that rely exclusively on historical-cultural aspects or that sustain an economic bias. We use bibliographic and journalistic sources, from which we develop our own interpretation of the period. Thus, we observe that clientelist practices are encouraged to manifest themselves at the level of national political organization particularly within the federal sphere yet are also reflected at state and municipal levels, due to the coalition of political forces created through the implantation of a neoliberal project in Brazil. The latter has joined modern Brazilian social democracy and old regional oligarchies situated primarily within the PFL, PP, PTB and certain sectors of the PMDB, whose representatives are known for their attachment to patrimonialist and paternalistic practices. The inclusion of the latter in the conservative pact that has promoted neo-liberal political reform has thus meant awarding new value to such practices. Herein lies partial explanation for the vigor with which practices such as fisiologismo, apadrinhamento, abuse of state machinery, buying and selling of votes and clientelism have manifested themselves on the national scene over the course of the 1990s.

Semen variables of sheep (Ovis aries) experimentally infected with Toxoplasma gondii

The influence of Toxoplasma gondii on semen variables and sperm morphology of sheep was evaluated in eight reproductive males distributed into three experimental groups: GI, three sheep inoculated with 2.0 × 105 of P strain oocytes; GII, three sheep infected with 1.0 × 106 of RH strain tachyzoites and; GIII two control sheep. Clinical (rectal temperature, cardiac and respiratory frequencies), parasite and serology exams (IIF) were realized. Sperm variables (volume, motility, vigor and concentration) and semen morphology for each sheep were also evaluated. Thus, semen and blood collections were assessed on post-inoculation days (PIDs)-1,3,5,7,11,14 and weekly thereafter up to PID 70. Clinical alterations were observed (hypothermia and anorexia) in infected sheep from groups GI and GII. Parasitic outbreaks were detected in five sheep. All the infected sheep produced antibodies against T. gondii from PID 5 onwards, reaching a peak of 4096 and 8192 for group GI and GII sheep, respectively. Differences (P < 0.05) were observed regarding the ejaculate volume between the inoculated groups (oocytes and tachyzoites) and control. Even though experimental toxoplasmic infection resulted in clinical symptomology in the inoculated sheep, the minimal alterations in sperm pathologies could not be directly attributed to T. gondii. © 2008 Elsevier B.V. All rights reserved.

Biometria e qualidade fisiológica de sementes de diferentes matrizes de Tabebuia chrysotricha (Mart. Ex A. DC.) Stand I.

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

América Latina y el Caribe: la propiedad intelectual después de los tratados de libre comercio

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Qualidade fisiológica de sementes de Brachiaria e avaliação da produtividade de massa seca em diferentes sistemas de integração lavoura-pecuária sob irrigação

The speed and magnitude of tropical pastures expansion in Brazil are related to the availability of quality seeds. This research aimed to evaluate the physiological quality of seeds of two Brachiaria species submitted to germination and viability tests and also estimate, for both species, the fresh and dry mass yield, under different irrigated crop-livestock integration systems. For field analysis, the experimental design was a randomized complete block, in subplots, with four intercrops in the plot (Brachiaria brizantha cv. Marandu and Brachiaria ruziziensis simultaneously established with corn and nitrogen fertilization coverage), and four forage cutting times, in the winter/spring season, in subplots, with four replications. In the laboratory, the experimental design was completely randomized, with four replications per treatment/test. The germination and viability tests indicated that B. brizantha seeds showed higher physiological quality, when compared with B. ruziziensis, while the tetrazolium test and germinated seedlings characteristics were similar. The B. ruziziensis, simultaneously intercropped with corn, was the less viable intercrop, due to the lower fresh and dry mass yield and litter deposition on the soil surface. In general, the pasture formation for the second season cultivation, intercropped with corn, was an excellent alternative for crop-livestock integration under a no-tillage system.

Testes de envelhecimento acelerado e de condutividade elétrica em sementes de Dictyoloma vendellianum A. Juss.

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Metodología para la comparación de los gastos militares

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Implementación de obligaciones sobre propiedad intelectual de los tratados de libre comercio con EE.UU.: experiencia de Chile

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Primera evaluación de los regímenes de origen contenidos en los acuerdos comerciales suscritos entre la Unión Europea y los países de América Latina y el Caribe

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La liberalización del sector de servicios: el caso del Tratado Unión Europea

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