[Helsinki] 24/6 1945

Kirje 24.6.1945

Customer Focus Newsletter, January-February, 2009, Vol. 6, no.1

A bi-monthly bulletin to keep the department/agency management teams of state government better informed. We hope to consolidate most of the service update messages we send throughout the month and keep you updated about the work of the Customer Councils. If yours is one of the many departments who participated in the second annual DAS customer satisfaction survey recently, we thank you for taking the time to give us this important feedback. We look forward to sharing survey results with you, and pledge to consider responses carefully as we work to determine benchmarks and set future priorities.

EPI Update, February 6, 2009

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Hyperpolarized lithium-6 as a sensor of nanomolar contrast agents.

Lithium is widely used in psychotherapy. The (6)Li isotope has a long intrinsic longitudinal relaxation time T(1) on the order of minutes, making it an ideal candidate for hyperpolarization experiments. In the present study we demonstrated that lithium-6 can be readily hyperpolarized within 30 min, while retaining a long polarization decay time on the order of a minute. We used the intrinsically long relaxation time for the detection of 500 nM contrast agent in vitro. Hyperpolarized lithium-6 was administered to the rat and its signal retained a decay time on the order of 70 sec in vivo. Localization experiments imply that the lithium signal originated from within the brain and that it was detectable up to 5 min after administration. We conclude that the detection of submicromolar contrast agents using hyperpolarized NMR nuclei such as (6)Li may provide a novel avenue for molecular imaging.

Radiopuhe Stalinin kuoleman johdosta 6.3.1953

Puhe

Helsinki 23/6 -33

Kirje 23.6.1933

EPI Update, March 6, 2009

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Kniemi 6/9 -24

Kirje 6.9.1924

Angervonniemellä 6.8.1929

Kirje