Factors regulating skeletal muscle fatty acid oxidative genes

Skeletal muscle is the most significant site for whole body fat utilisation. The ability to regulate fat use has a significant impact on the development of obesity and Type II diabetes. The studies conducted during this PhD provided significant insight into the complex molecular regulation of skeletal muscle fat utilisation.

Enhancements to fraud and deception prevention in open multi-agent marketplaces

Fraud and deception in online marketplaces has been an on-going problem. This thesis proposes novel techniques and mechanisms using agent technology to protect buyers and sellers in online environments such as eBay. The proposed solution has been rigorously tested and the results show good commercial promise.

Agent-based heuristics to solve NP-hard scheduling problems

A novel agent-driven heuristic approach was developed to control the operational scheduling for a local manufacturer. This approach outperformed the traditional kanban control mechanism under numerous simulated benchmarking tests. Using this approach, the individual machine loading was reduced by, on average, 28%, with the loading spread reduced by 85%

Factors regulating noradrenaline overflow in the rat brain in vivo and in vitro

High concentrations of the neurotransmitter noradrenaline and the co-transmitter NPY have been reported in discrete regions of the hypothalamus. This study suggests the NPY plays a possible role in the hypothalamus during the pathophysiological condition of ageing possibly through an NPY Y1 receptor. It also provides further evidence for an interaction between NPY and noradrenaline in the central nervous system.

Co-ordination in multi-agent systems

A multi-agent system is a complex software system which is composed of many relative autonomous smaller softwares called agents. The research on multi-agent systems is concerned with the interaction and coordination among these agents to let them help each other to solve complicated problems, such as finance investment management. The principal contributions represented by these 50 selected papers are "cooperation under uncertainty in distributed expert systems (DESs)", "a tool and algorithms to build DESs", and "information gathering and decision making in multi-agent systems (MASs)".

Professional identity in the global sports entertainment industry : regulating the body, mind and soul of Australian Football League footballers

In this article we discuss the ways in which the professional identity of Australian Football League (AFL) footballers — in a physical, high body contact sport — is shaped by concerns to develop different aspects of the body, mind and soul of the young men who want to become AFL footballers. Drawing on Michel Foucault’s later work on the care of the self we argue that narratives of identity necessarily involve a struggle for the body, mind and soul of these young men. Foucault’s work enables us to identify and analyse how relations of power, forms of regulation and arts of governing interact in ongoing attempts to develop the professional footballer. The article explores these issues via an analysis of the rationalities and techniques that inform talent identification and player management practices; and risk management in relation to these practices and processes in the AFL.

An agent architecture for managing data resources in a grid environment

The agent paradigm has been successfully used in a large number of research areas. MAPFS, a parallel file system, constitutes one successful application of agents to the I/O field, providing a multiagent I/O architecture. The use of a multiagent system implies coordination and cooperation among its agents. MAPFS is oriented to clusters of workstations, where agents are applied in order to provide features such as caching or prefetching. The adaptation of MAPFS to a grid environment is named MAPFS-Grid. Agents can help to increase the performance of data-intensive applications running on top of the grid.

This paper describes the conceptual agent framework and the communication model used in MAPFS-Grid, which provides the management of data resources in a grid environment. The evaluation of our proposal shows the advantages of using agents in a data grid.

An agent-based hybrid system for microarray data analysis

This article reports our experience in agent-based hybrid construction for microarray data analysis. The contributions are twofold: We demonstrate that agent-based approaches are suitable for building hybrid systems in general, and that a genetic ensemble system is appropriate for microarray data analysis in particular. Created using an agent-based framework, this genetic ensemble system for microarray data analysis excels in both sample classification accuracy and gene selection reproducibility.

Climate change in the Victorian Alps : can VET be a change agent?

Of all the factors contributing to turbulent times in Australia, climate change is one that offers both challenges and opportunities for VET. In a time when the response to water availability is subject to ‘extensive debate and policy attention’, our presentation explores what adults living and working in the Alpine region of Victoria understand about the changes to water availability, and what they have learned about adapting to significant climatic changes in their local area. Interviews were conducted in the towns of Bright, Mount Beauty and Albury, with participants from across the Alpine region. Our study found evidence of a strong understanding of the direct impact of climate change on participants’ local community area, and a keen desire to learn about adaptation to change. In addition to an identified need for more information around climate change issues and projected impacts in general, participants saw practical hands-on water education strategies as an important way to educate people to help themselves. Conversations about where or how people learned to adapt to change were broad ranging, and clearly connected to the participants’ backgrounds, livelihoods or where they were situated. This raised the question of what responses VET might develop to address these identified learning needs. Major local industries
of tourism, agriculture, water harvesting and land care are all covered by national Training Packages that include industry- specific units of competence to support learning to live and work in an environmentally sustainable way. In addition, the national Employability Skills framework offers opportunities to build climate change awareness and adaptation into units of competency where they may not be explicitly incorporated. Our presentation will outline the opportunities for VET to act as a change agent in this and other Australian communities impacted by climate change.

Incorporating fairness into development of an integrated multi-agent online dispute resolution environment

The paper describes the development of an integrated multi-agent online dispute resolution environment called IMODRE that was designed to assist parties involved in Australian family law disputes achieve legally fairer negotiated outcomes. The system extends our previous work in developing negotiation support systems Family_Winner and AssetDivider. In this environment one agent uses a Bayesian Belief Network expertly modeled with knowledge of the Australian Family Law domain to advise disputants of their Best Alternatives to Negotiated Agreements. Another agent incorporates the percentage split of marital property into an integrative bargaining process and applies heuristics and game theory to equitably distribute marital property assets and facilitate further trade-offs. We use this system to add greater fairness to Family property law negotiations.

Negotiation strategy for mobile agent-based e-negotiation

Negotiation is a vital component of electronic trading. It is the key decision-making approach used to reach consensus between trading partners. Generally, the trading partners implement various negotiation strategies in an attempt to maximize their utilities. As negotiation strategies have impact on the outcomes of negotiation, it is imperative to have efficient negotiation strategies that truly maximize clients’ utilities. In this paper, we propose a multi-attribute mobile agent-based negotiation strategy that maximizes client’s utility. The strategy focuses on one-to-many bilateral negotiation. It considers different factors that have significant effect on the scheduling of various negotiation phases: offer collection, evaluation, negotiation, and bid settlement. The factors include offers expiry time, market search space, communication delays, processing queues, and transportation times. We reasoned about the correctness of the proposed negotiation strategy with respect to the existing negotiation strategies. The analysis showed that the proposed strategy boosts client’s utility, shortens negotiation time, and ensures adequate market search.

Synthesis of silica-coated ZnO nanocomposite : the resonance structure of polyvinyl pyrrolidone (PVP) as a coupling agent

Abstract The preparation of silica-coated ZnO nanocomposite using polyvinyl pyrrolidone (PVP) as a coupling agent was investigated. Transmission electron microscopy analysis revealed that silica has been deposited on the surface of PVP-capped ZnO nanoparticles as a continuous thin layer. Two-dimensional correlation analysis based on the time-dependent UV–vis spectra was introduced to study the interaction governing the deposition of silica on to PVP-capped ZnO. Strong hydrogen bonds formed between the amphiphilic PVP molecules and silica in the silicacoated PVP-capped ZnO composites. The reduced photocatalytic activity of silica-coated ZnO nanoparticles will enhance their performance as durable, safe, and nonreactive UV blockers in plastics, paints, and coating for outdoor textile and timber products.

Marsupial milk : identifying signals for regulating mammary function and development of the young

The role of milk in providing nutrition for the young is well established. However, it is becoming apparent that milk has a more comprehensive role in programming and regulating growth and development of the suckled young, and an autocrine impact on the mammary gland so that it functions appropriately during the lactation cycle. This central role of milk is best studied in animal models, such as marsupials that have evolved a different lactation strategy to eutherians and allow researchers to more easily identify regulatory mechanisms that are not as readily apparent in eutherian species. For example, the tammar wallaby (Macropus eugenii) has evolved with a unique reproductive strategy of a short gestation, birth of an altricial young and a relatively long lactation during which the mother progressively changes the composition of the major, and many of the minor components of milk. Thus, in contrast to eutherians, there is a far greater investment in development of the young during lactation and it is likely that many of the signals that regulate development of eutherian embryos in utero are delivered by the milk. This requires the co-ordinated development and function of the mammary gland. Inappropriate timing of these signalling events in mammals may result in either limited or abnormal development of the young, and potentially a higher incidence of mature onset disease. The tammar is emerging as an attractive model to better understand the role of milk factors in these processes.