1000 resultados para Participación local


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Apresenta o quadro teórico e metodológico da pesquisa Janelas da Cultura Local, em implementação no Instituto Brasileiro de Informação em Ciência e Tecnologia com apoio do Conselho Nacional de Desenvolvimento Científico e Tecnológico, que tem como objetivo promover, de forma participativa, ações de informação no sentido da inclusão digital. As premissas do projeto - a informação como força de transformação, a responsabilidade social da ciência da informação e a sua relação intrínseca com a tecnologia da informação - se manifestam na proposta de desenvolvimento de competências para produção e comunicação digital da informação, contribuindo para dotar os participantes de elementos de mediação entre a cultura local e a cultura global. Espera-se, com o projeto, trazer contribuição ao resgate e registro da memória cultural da comunidade envolvida na pesquisa, contribuindo, também, para elevação do Índice de Desenvolvimento Humano no município beneficiado.

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Relata os resultados parciais da pesquisa Janelas da Cultura Local: Quissamã, RJ, em desenvolvimento pelo Grupo de Pesquisa Informação e Inclusão Social do Ibict, com apoio do Conselho Nacional de Desenvolvimento Científico e Tecnológico. Registra e oferece à discussão a abordagem teórica e metodológica aplicada ao projeto e, ao mesmo tempo, divulga uma informação sobre a responsabilidade social da ciência da informação, no Brasil. O projeto é implementado em parceria com a Secretaria Municipal de Educação e Cultura de Quissamã, RJ, e tem como campo de pesquisa a Escola Municipal Maria Ilka, no bairro Santa Catarina. Além do relatório científico, que incluirá sugestão de uma metodologia para inclusão digital de comunidades, espera-se como resultado a aquisição de competências em informação pelos participantes locais, e especialmente, contribuir para promover o resgate e o registro da memória cultural do dessa comunidade.

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A new method is used to estimate the volumes of sediments of glacial valleys. This method is based on the concept of sloping local base level and requires only a digital terrain model and the limits of the alluvial valleys as input data. The bedrock surface of the glacial valley is estimated by a progressive excavation of the digital elevation model (DEM) of the filled valley area. This is performed using an iterative routine that replaces the altitude of a point of the DEM by the mean value of its neighbors minus a fixed value. The result is a curved surface, quadratic in 2D. The bedrock surface of the Rhone Valley in Switzerland was estimated by this method using the free digital terrain model Shuttle Radar Topography Mission (SRTM) (~92 m resolution). The results obtained are in good agreement with the previous estimations based on seismic profiles and gravimetric modeling, with the exceptions of some particular locations. The results from the present method and those from the seismic interpretation are slightly different from the results of the gravimetric data. This discrepancy may result from the presence of large buried landslides in the bottom of the Rhone Valley.

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PURPOSE: Local breast cancer relapse after breast-saving surgery and radiotherapy is associated with increased risk of distant metastasis formation. The mechanisms involved remain largely elusive. We used the well-characterized 4T1 syngeneic, orthotopic breast cancer model to identify novel mechanisms of postradiation metastasis. EXPERIMENTAL DESIGN: 4T1 cells were injected in 20 Gy preirradiated mammary tissue to mimic postradiation relapses, or in nonirradiated mammary tissue, as control, of immunocompetent BALB/c mice. Molecular, biochemical, cellular, histologic analyses, adoptive cell transfer, genetic, and pharmacologic interventions were carried out. RESULTS: Tumors growing in preirradiated mammary tissue had reduced angiogenesis and were more hypoxic, invasive, and metastatic to lung and lymph nodes compared with control tumors. Increased metastasis involved the mobilization of CD11b(+)c-Kit(+)Ly6G(high)Ly6C(low)(Gr1(+)) myeloid cells through the HIF1-dependent expression of Kit ligand (KitL) by hypoxic tumor cells. KitL-mobilized myeloid cells homed to primary tumors and premetastatic lungs, to give rise to CD11b(+)c-Kit(-) cells. Pharmacologic inhibition of HIF1, silencing of KitL expression in tumor cells, and inhibition of c-Kit with an anti-c-Kit-blocking antibody or with a tyrosine kinase inhibitor prevented the mobilization of CD11b(+)c-Kit(+) cells and attenuated metastasis. C-Kit inhibition was also effective in reducing mobilization of CD11b(+)c-Kit(+) cells and inhibiting lung metastasis after irradiation of established tumors. CONCLUSIONS: Our work defines KitL/c-Kit as a previously unidentified axis critically involved in promoting metastasis of 4T1 tumors growing in preirradiated mammary tissue. Pharmacologic inhibition of this axis represents a potential therapeutic strategy to prevent metastasis in breast cancer patients with local relapses after radiotherapy. Clin Cancer Res; 18(16); 4365-74. ©2012 AACR.

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Iowa Counties have been experiencing significant tort claim liability due to the signing of local roads. One such problem is relative to the real or alleged need for signing at uncontrolled intersections of local roads. It has been assumed that the standard CROSS ROAD sign, which calls for a yellow diamond with a black cross, was sufficient to provide the necessary warning that a driver may be approaching an intersection which requires special precautionary driving attention. However, it is possible that this sign on a through highway might conflict with the legal status of the local county road. In light of this situation, it seemed worthwhile to know the extent to which uncontrolled local road intersections were perceived as a potential liability problem; the degree to which the standard CROSS ROAD sign communicated to the driver the message a county engineer wanted at these local road intersections; and whether there were any better signing alternatives available to communicate this hazard to the driver in this situation.

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The article begins with the theoretical bases for developing a training programme to foment the exercise of an active participation. The designed program is applied in a group of women with different cultural backgrounds that live in the city of L'Hospitalet and it is evaluated following the methodological characteristics of an investigation evaluation of participatory character. From the collection and analysis of the information, we present the results obtained that turn around the investigation objectives: the validation of the program design, the investigation on the exercise of active participation, the formation of the work team and the creation of a meeting point for women. El artículo se inicia con las bases teóricas para elaborar un programa de formación para fomentar el ejercicio de una participación activa. El programa diseñado se aplica en un grupo de mujeres con diferentes orígenes culturales que viven en la ciudad de L¿Hospitalet, y se evalúa siguiendo las características metodológicas de una investigación evaluativa de carácter participativo. A partir de la recogida y análisis de la información, se presentan los resultados que giran en torno a los objetivos de la investigación: la validación del programa, la investigación sobre el ejercicio de la participación, la formación del equipo de trabajo y la creación de un espacio de encuentro de mujeres.

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Este artículo parte de las bases teóricas y metodológicas fundamentales para la elaboración, aplicaciónes y evaluación de un programa de formación para una participación activa e intercultural específicamente diseñado para mujeres. El programa sigue una metodología de evaluación participativa, que incluye la participación de los sujetos en todo el proceso de la evaluación. Presentamos un modelo de evaluación participativa: la evaluación diagnóstica que incluye el origen del proyecto, un análisis en profundidad de mujeres inmigrantes sobre su ejercicio de la participación y un análisis del contexto de aplicación; la evaluación de la aplicación que contiene una síntesis el trabajo desarrollado durante las sesiones; y la evaluación final que analiza los efectos del programa con respecto a los objetivos y necesidades identificadas en el diagnóstico.

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The article begins with the theoretical bases for developing a training programme to foment the exercise of an active participation. The designed program is applied in a group of women with different cultural backgrounds that live in the city of L'Hospitalet and it is evaluated following the methodological characteristics of an investigation evaluation of participatory character. From the collection and analysis of the information, we present the results obtained that turn around the investigation objectives: the validation of the program design, the investigation on the exercise of active participation, the formation of the work team and the creation of a meeting point for women. El artículo se inicia con las bases teóricas para elaborar un programa de formación para fomentar el ejercicio de una participación activa. El programa diseñado se aplica en un grupo de mujeres con diferentes orígenes culturales que viven en la ciudad de L¿Hospitalet, y se evalúa siguiendo las características metodológicas de una investigación evaluativa de carácter participativo. A partir de la recogida y análisis de la información, se presentan los resultados que giran en torno a los objetivos de la investigación: la validación del programa, la investigación sobre el ejercicio de la participación, la formación del equipo de trabajo y la creación de un espacio de encuentro de mujeres.

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Este artículo parte de las bases teóricas y metodológicas fundamentales para la elaboración, aplicaciónes y evaluación de un programa de formación para una participación activa e intercultural específicamente diseñado para mujeres. El programa sigue una metodología de evaluación participativa, que incluye la participación de los sujetos en todo el proceso de la evaluación. Presentamos un modelo de evaluación participativa: la evaluación diagnóstica que incluye el origen del proyecto, un análisis en profundidad de mujeres inmigrantes sobre su ejercicio de la participación y un análisis del contexto de aplicación; la evaluación de la aplicación que contiene una síntesis el trabajo desarrollado durante las sesiones; y la evaluación final que analiza los efectos del programa con respecto a los objetivos y necesidades identificadas en el diagnóstico.

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This handbook deals with the duties and responsibilities of a mayor of a city, a member of a county board of supervisor or a sheriff of a county from the standpoint of their relationship with a county/municipal civil defense and emergency planing administration.

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A benefit-cost analysis was used to examine the effects of alternative investment strategies on the local rural road system. The study first estimated the change in costs to the traveling public of various investment strategies, then compared the change for each investment strategy to the cost of implementing that strategy on the county rural road system. The basic purpose of this study was to develop guidelines for local supervisors and engineers in evaluating investment or disinvestment proposals, and to provide information to state legislatures in developing local rural road and bridge policies. Three case study areas of 100 sq mi each were selected in Iowa. A questionnaire was used to collect data from farm and non-farm residents in the study areas. Data were obtained on the number of 1982 trips by origin, destination, and type of vehicle.