Classical solutions for D-branes in AdS

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Aspectos da biologia reprodutiva da arara-azul Anodorhynchus hyacinthinus (Latham, 1790) no mosaico Carajás-PA

Pós-graduação em Ciências Biológicas (Zoologia) - IBB

Structure of importin-a from a filamentous fungus in complex with a classical nuclear localization signal

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

From quantum to classical instability in relativistic stars

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Dynamics of classical particles in oval or elliptic billiards with a dispersing mechanism

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Classical and quantum N = 1 super W∞-algebras

We construct higher-spin N = 1 superalgebras as extensions of the super-Virasoro algebra containing generators for all spins s ≥ 3/2. We find two distinct classical (Poisson) algebras on the phase superspace. Our results indicate that only one of them can be consistently quantized.

Expression of the classical and nonclassical HLA molecules in breast cancer

Considering that downregulation of HLA expression could represent a potential mechanism for breast carcinogenesis and metastasis, the aim of the present study was to use immunohistochemical methods to analyze the expression of HLA-Ia, HLA-DR, HLA-DQ, HLA-E, and HLA-G in invasive ductal carcinoma (IDC) of the breast and to relate this HLA profile to anatomopathological parameters. Fifty-two IDC from breast biopsies were stratified according to histological differentiation (well, moderately, and poorly differentiated) and to the presence of metastases in axillary lymph nodes. The expression of HLA molecules was assessed by immunohistochemistry, using a computer-assisted system. Overall, 31 (59.6%) out of the 52 IDC breast biopsies exhibited high expression of HLA-G, but only 14 (26.9%) showed high expression of HLA-E. A large number (41, 78.8%) of the biopsies showed low expression of HLA-Ia, while 45 (86.5%) showed high expression of HLA-DQ and 36 (69.2%) underexpressed HLA-DR. Moreover, 24 (41.2%) of 52 biopsies had both low HLA-Ia expression and high HLA-G expression, while 11 (21.2%) had low HLA-Ia expression and high HLA-E expression. These results suggest that, by different mechanisms, the downregulation of HLA-Ia, HLA-E, and HLA-DR and the upregulation of HLA-G and HLA-DQ are associated with immune response evasion and breast cancer aggressiveness.

Efeitos do estímulo auditivo musical sobre a resposta autonômica cardíaca e parâmetros cardiorrespiratórios durante e após exercício submáximo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Carimbó do Santo Preto: a presença negra na performance musical da festividade do Glorioso São Benedito em Santarém Novo (PA)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Eventos extremos de precipitação em Belém-PA: uma revisão de notícias históricas de jornais

Os impactos socioeconômicos dos Eventos Extremos de Precipitação Diária em Belém-Pará foram estudados com base em histórias relatadas nas notícias dos jornais da cidade durante o período de 1987 a 2009. Estes eventos foram caracterizados como extremos por meio da Técnica do Decil. O objetivo foi identificar as consequências e os principais bairros afetados pelos eventos extremos de precipitação diária. Os anos que estiveram sob influência do fenômeno El Niño (La Niña) foram os que apresentaram menor (maior) frequência de Eventos Extremos de Precipitação e de noticias publicadas nos jornais da cidade. A variação mensal mostrou que os Eventos Extremos e as notícias dos jornais foram maiores no período "mais chuvoso" (verão/outono austral). As histórias relatadas nas notícias dos jornais da cidade indicaram que o alagamento das ruas é a principal consequência dos eventos extremos para a cidade de Belém-Pará e os bairros mais afetados são Cremação, Jurunas e Batista Campos. Esses bairros são vizinhos e tem como fator comum a presença da bacia hidrográfica da Travessa Quintino Bocaiúva, a qual apresenta baixa declividade e dificulta o escoamento da água, favorecendo a formação de pontos de alagamentos. Identificou-se que a falta de infraestrutura da cidade é o fator predominante quanto à consequência dos eventos extremos de precipitação diária.

Oscilações climáticas Plio-Pleistocênicas e sua influência na prospecção de ouro na área do garimpo do Manelão (PA)

No garimpo do Manelão, o ouro está associado a veios de quartzo encaixados na seqüência metavulcano-sedimentar São Manoel. No período Plio-Pleistoceno, sob um clima úmido, desenvolveu-se sobre a seqüência São Manoel uma cobertura laterítica autóctone e imatura. Essa cobertura residual contém partículas de ouro com elevada pureza, sugerindo processos de lixiviação da liga Au-Ag ou de remobilização e redeposição do Au em ambiente laterítico. Durante o Pleistoceno, o clima tornou-se árido a semi-árido, favorecendo a erosão parcial da cobertura laterítica, através dos processos coluviais associados a enxurradas periódicas. Esse depósito coluvial recobre o perfíl laterítico, destruindo um possível padrão de dispersão geoquímica do ouro supergênico e prejudicando a prospecção geoquímica de superfície. No final do Pleistoceno e início do Holoceno, o clima úmido retorna, juntamente com os processos de intemperismo, formando stone line e latossolos. As coberturas laterítica e coluvial serviram de área-fonte para os aluviões atuais a subatuais do igarapé São Manoel, onde o ouro ocorre livre nos estratos sedimentares mais basais, formando concentrações da ordem de 10 g/ton.

Hamlet's Ophelia: The Changing Perceptions of Suicide, Death, and Madness in the Elizabethan and Victorian Periods

William Shakespeare's Hamlet, Prince of Denmark has been the source of question, debate, and research since its theatrical debut. In the midst of readings performances and one particular question has remained open and unresolved: was Ophelia's death an accident or a suicide? Some see Ophelia's death as an accident; others see it as a suicide resulting from the accumulation of a series of unfortunate events: her rejection by her boyfriend, her father’s murder, and her possible pregnancy. This paper will explore that age-old question from the perspectives of two historically different audiences: those of sixteenth-century and nineteenth-century England. I will argue that, despite the 300-year expanse between these two audiences, both emerged with the same conclusion: Ophelia's death was accidental. However, cultural and scientific changes affected the reasons why each came to that conclusion.

Carimbó do Santo Preto: a presença negra na performance musical da festividade do Glorioso São Benedito em Santarém Novo (PA)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The Ground State Energy per Site of the Quantum and Classical Edwards-Anderson Spin Glass in the Thermodynamic Limit

We derive general rigorous lower bounds for the average ground state energy per site e ((d)) of the quantum and classical Edwards-Anderson spin-glass model in dimensions d=2 and d=3 in the thermodynamic limit. For the classical model they imply that e ((2))a parts per thousand yena'3/2 and e ((3))a parts per thousand yena'2.204a <-.

Impact of Glucocorticoid Receptor Gene Polymorphisms on the Metabolic Profile of Adult Patients with the Classical Form of 21-Hydroxylase Deficiency

Background: CAH patients have an increased risk of cardiovascular disease, and it remains unknown if lifelong glucocorticoid (GC) treatment is a contributing factor. In the general population, glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. Our aim was to analyze the association between the NR3C1 polymorphisms and the metabolic profile of CAH patients. Methodology: Sixty-eight adult patients (34SV/34SW) with a mean age of 28.4 +/- 9 years received dexamethasone (mean 0.27 +/- 0.11 mg/day) to obtain normal androgen levels. SW patients also received fludrocortisone (50 mu g/day). Metabolic syndrome (MetS) was defined by the NCEP ATPIII criteria and obesity by BMI >= 30 kg/m(2). NR3C1 alleles were genotyped, and association analyses with phenotype were carried out with Chi-square, t-test and regression analysis. Results: Obesity and MetS were observed in 23.5% and 7.3% of patients, respectively, and were not correlated with GC doses and treatment duration. BMI was positively correlated with blood pressure (BP), triglycerides (TG), LDL-c levels and HOMA-IR and inversely correlated with HDL-c levels. BclI and A3669G variants were found in 26.4% and 9.6% of alleles, respectively. Heterozygotes for the BclI polymorphism presented with higher BMI (29 kg/m(2) +/- 5.3 vs. 26 kg/m(2) +/- 5.3, respectively) and waist circumference (89 cm +/- 12.7 vs. 81 cm +/- 13, respectively) compared to wild-type subjects. Hypertension was found in 12% of patients and heterozygotes for the BclI polymorphism presented higher systolic BP than wild type subjects. Low HDL-c and high TG levels were identified in 30% and 10% of patients, respectively, and were not associated with the NR3C1 polymorphisms. A3669G carriers and non-carriers did not differ. Conclusion: In addition to GC therapy, the BclI GR variant might play an important role in obesity susceptibility in CAH patients. Genotyping of GR polymorphisms could result in the identification of a subgroup at risk patients, allowing for the establishment of personalized treatment and the avoidance of long-term adverse consequences.