979 resultados para Ossos - Anatomia


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The present study was carried out to evaluate the effect of statins associated with physical exercise (PE) in liver cells in dyslipidemic rats through cariometry. The animals were divided into six groups: animals subjected to a hypercholesterolemic diet (HD), simvastatin, with (G1) and without (G2) physical exercise (PE); HD submitted (G3) or not (G4) to PE, and commercial food diet (F) with (G5) and without (G6) PE. Histological analysis of the liver was performed by staining the slides with hematoxylin and eosin. The cariometric study included measuring the major and minor diameters of the hepatocytes nuclei. The Shapiro-Wilk test was also performed. To determine the differences among the groups, the Kruskal-Wallis Test with Dunn's post-test were conducted. The significance level was set at 5%. No difference was found in the hepatocytes nuclei between G5 and G6. When these groups were related with G3 and G4, reduced nuclei were observed. There was no difference between G1 and G6. The comparison between G6 and G2 showed that the nuclei in G2 were smaller. No difference was detected between G5 and G1. Changes were observed in the nuclei shape in G2 in comparison to G1. Considering G2 and G3, a decrease in the size of nuclei was observed in G3. On the other hand, G2 showed changes in shape in the comparative analysis with G4. The size and shape of G1 nuclei were larger than G3 as well as changes in shape were observed when compared to G4. G4 showed smaller nuclei than G3. Therefore, F, associated or not with the practice of PE, does not alter the size and shape of the hepatocytes nuclei; HD combined with sedentarism influences changes in the morphometric parameters of hepatocytes; and the association of simvastatin and PE seems to protect the hepatocytes nuclei with regard to HD.

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Pós-graduação em Zootecnia - FCAV

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Os processos mastóideos de 305 crânios humanos identificados foram estudados com a finalidade de melhor compreender suas características morfológicas básicas, bem como suas relações com outras formações ósseas da área mastóidea. Foram mensuradas, além das várias medidas gerais do crânio, a altura e a largura dos processos mastôideos, a distância bimastóidea e bi-supramastóidea. Foram estudados: a incidência e a forma do processo paramastóideo, do sulco do processo mastóideo e da rugosidade da superfície lateral do processo mastóideo. Todos os resultados ósseos foram submetidos à análise estatística, relacionando-os ao sexo, grupo étnico e forma do crânio. Objetivando um melhor entendimento das formações anatómicas que se relacionam com os processos mastóideos, foram dissecados, em vinte cabeças humanas (quarenta lados), os músculos estemocleidomastóideo, esplênio da cabeça, longo da cabeça e ventre posterior do digástrico. As inserções destes músculos foram mensuradas, tendo-se como referência o plano aurículo-orbital. As áreas de fixação no osso foram medidas através de um analisador de imagens. De maneira geral as características ósseas estudadas mostraram que existem diferenças estatísticas significantes nos grupos formados por sexo e forma do crânio. Os caracteres estudados para a determinação do sexo dos crânios mostraram-se estatisticamente confiáveis, indicando a possibilidade da utilização do processo mastóideo para a determinação do sexo de crânios humanos. As dissecções realizadas mostraram que há relação funcional entre os músculos e as formações ósseas da área mastóidea, principalmente entre o ventre posterior do músculo digástrico e o processo paramastóideo

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The aim of this study was to evaluate the influence of the bed in High Density Porous Polyethylene (Medpor) implants integration. Two different kind of beds -- corticalized and decorticalized -- were made in six dogs. The animals were killed thirty, sixty and ninety days after implantation. Blocks including implant and adjacent bone were harvested, submitted to histological procedures, stained in hematoxiline-eosine and analyzed in optic microscope. The results demonstrated an absence of infection and foreign body reaction associated with High Density Porous Polyethylene (Medpor) implants. Furthermore, bony and fibrovascular ingrowth could be observed into its pores. The best integration was noted in decorticalized group, in which occurred a greater bony and fibrovascular ingrowth in comparison to the corticalized group

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)