Relationships between oral infections and blood glucose concentrations or hba1c levels in normal and diabetic rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Healing of normal and osteopenic bone with titanium implant and low-level laser therapy (GaAlAs): a histomorphometric study in rats

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação sensorial de adolescentes com desenvolvimento normal na faixa etária de 11 a 18 anos

Tactile sensibility allows for adequate neuropsychomotor development. In addition, it enables the understanding of the subject’s own body, actions and explorations of objects, people and the environment. Previous studies have evaluated 3 to 10 year-old children. Herein, we evaluate the tactile sensibility in adolescents. The aim of this study was to verify whether the rapid growth of the body changes the normal pattern of tactile sensibility in adolescents. Furthermore, we provide evaluation material that is easy to use, simple, and secure to handle, designed to attend the specific age range studied. Thirty-two young participants between 11 and 18 years old, sixteen males and sixteen females, were evaluated. The adolescents go to public school and present normal development patterns. Graphesthesia, stereognosia, and Semmes-Weinstein monofilament tests were performed to evaluate the sensibility on the ventral and dorsal sides of the right and left hands. A questionnaire was used to identify the relevant activities performed with the hands during the studied period. The adolescents tested were collaborative during the research and presented curiosity regarding the boxes used in the experiment. Results indicated alterations in the tactile sensibility on the dorsal side of the hands from 13-year- old males. The major activities indicated by the adolescents were writing and sports for males and writing and cleaning for females. First evidences of possible changes in the normal tactile sensibility during adolescence were observed in this study.

Detecção do HPV e EBV por nPCR em líquen plano bucal e tecido normal de cavidade bucal

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Sexual Precocity of Nellore Bulls that are Offspring of Super Precocious, Precocious and Normal Cows in Extensive Farming Conditions

Contents The objective of this work was to verify that mothers classified as super precocious (M1) and precocious (M2) produce more precocious bulls than females classified as normal (M3). This study included 21186 animals with an average age of 21.29 +/- 1.77months that underwent a breeding soundness evaluation from 1999 to 2008. Of these animals, 2019, 6059 and 13108 were offspring of M1, M2 and M3 females, respectively. In the breeding soundness examination, the animals were classified as sound for reproduction, sound under a natural mating regime, unsound for reproduction and discarded. To compare the averages obtained for each category of mother within the individual breeding soundness classes, a chi-square test with a 5% error probability was used, considering the effects of year and month of birth and farm. For the three classes of mothers (M1, M2 and M3), 67.26, 67.22 and 64.16% of bull calves were considered sound for reproduction and 19.71, 19.46 and 21.90% were considered unsound for reproduction, respectively. There was no difference in the frequency of animals that were sound for reproduction under the natural breeding regime between the three classes of mothers (8.87, 9.31 and 9.19%, respectively). There was a difference between the numbers of precocious and normal females that were discarded, with frequencies of 4.01 and 4.75%, respectively (p<0.05). There were differences in year and month of birth and farm between super precocious and precocious cows in relation to the breeding soundness classification of the animals. It was concluded that the bull offspring of super precocious and precocious cows presented a higher percentage of approval in the breeding soundness examination than the bull offspring of normal cows, demonstrating that the selection for precocity of females has contributed to an increase in the sexual precocity of the herd in relation to the sexual maturity of bulls.

Normal Forms for Codimension One Planar Piecewise Smooth Vector Fields

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Beneficial Effects of Adiponectin on Periodontal Ligament Cells under Normal and Regenerative Conditions

Type 2 diabetes and obesity are increasing worldwide and linked to periodontitis, a chronic disease which is characterized by the irreversible destruction of the tooth-supporting tissues, that is, periodontium. The mechanisms underlying the association of diabetes mellitus and obesity with periodontal destruction and compromised periodontal healing are not well understood, but decreased plasma levels of adiponectin, as found in diabetic and obese individuals, might be a critical mechanistic link. The aim of this in vitro study was to examine the effects of adiponectin on periodontal ligament (PDL) cells under normal and regenerative conditions, and to study the regulation of adiponectin and its receptors in these cells. Adiponectin stimulated significantly the expression of growth factors and extracellular matrix, proliferation, and in vitro wound healing, reduced significantly the constitutive tumor necrosis factor-alpha expression, and caused a significant upregulation of its own expression. The beneficial actions of enamel matrix derivative on a number of PDL cell functions critical for periodontal regeneration were partially enhanced by adiponectin. The periodontopathogen Porphyromonas gingivalis inhibited the adiponectin expression and stimulated the expression of its receptors. In conclusion, reduced levels of adiponectin, as found in type 2 diabetes and obesity, may compromise periodontal health and healing.

Entre livres e oficiais: a expansão do ensino normal em São Paulo (1927-1933)

Pós-graduação em Educação - FFC