1000 resultados para Mucopolissacaridose tipo 1


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The conservation of raw milk for long periods of time under refrigeration can result in the lost of its quality. This happens because bacterias, capable of developing in low temperatures, as psichrotrophics, in milk, associates with its enzymatic activities, are capable to degradate it. Although the pasteurization of milk sufficiently diminishes the transmission of the illnesses, that generally eliminates such microorganisms, is not a total efficient process because many enzymes produced for such bacterias are termostable, being able to resist the treatment and to remain active, leading to the loss of the quality of milk and its derivatives. The Normative Instruction 51 of 2002 established that milk must be cooled and stored in the production property, what resulted increasing the incidence of such bacteria in population destined milk. In some parts of the world contaminated milk is causing serious risks to the health of the population, assuming great importance in Public Health, mainly in relation to the hygienic-sanitary conditions of the product. ANVISA establishes, thus, maximum bacteriological concentration that must be evidenced before commercializing the product, guaranteeing the quality of milk as proper for consumption. Based on these aspects, the objective of this work is the microbiological analysis of 30 milk samples type C, collected in bakeries of the city Botucatu, in the state of São Paulo. Analysis were made to determinate the most likely number of termotolerants coliforms, as well the number of colony units of psichrotrophics bacterias, the presence of Salmonella and the enumeration of positive Staphylococcus aureus, at the moment of purchase and validity of the products

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It aims the comparison of these moments between an analytical plates theory and a computational numerical simulation. It is accented the details of studies about analytical theory as well the process, step by step, of a program that has as an influence the method of finite elements. The theory of plates has an extremely importance when it is talked about slabs and it takes as a base some fundamental hypotheses (that the middle point of the plate is considered flat and under formable) the points that are normal in relation to the middle surface is not considered because of its intensity that is irrelevant in comparison to the rest. The computational programs offer good results when they are applied in a correct way and, it resolves numerous functions in a short period of time. The objective is to highlight the importance of bending moments, its points of maximum and minimum, that has the objective of realize a good reinforcement sizing for a reinforced concrete. Furthermore, it can propitiate an economy in places that is demanded a small quantity of steel, before dimensioned for a load that is distributed in all the surface of the plate, at the same intensity

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Os distúrbios do sistema nervoso central mais comuns relatados no mundo são a ansiedade e a depressão, com grande incidência de casos nos quais aparecem juntos. Os tratamentos utilizados na clínica além de não serem efetivos na totalidade dos casos podem, por vezes, apresentar diversos efeitos não desejados. Assim, na busca novas drogas mais efetivas e com menor incidência de efeitos adversos, a Cananga odorata (Lam.) Hook. f. & Thomson aparece como uma alternativa. Esta espécie vegetal é utilizada na aromaterapia como na prevenção do estresse, ansiedade e depressão (BIRD, 2003). A busca de novas ferramentas terapêuticas depende do uso de animais de experimentação, e com as discussões na sociedade científica sobre o uso de animais, há uma maior preocupação em se desenvolver novas técnicas experimentais onde se possa aplicar os conceitos dos 3Rs objetivando a redução (Replacement) do número de animais, sua substituição (Reduction) e o refinamento (Refinement) das técnicas experimentais. Neste trabalho avaliou-se a atividade ansiolítica e antidepressiva do óleo essencial (OE) de Cananga odorata, em animais que foram sucessivamente submetidos a testes para avaliar a atividade motora, ansiolítica e antidepressiva. Camundongos machos foram tratados por via oral com OE nas doses de 0,1; 1, 10 e 100 mg/kg, e após 30 minutos foram submetidos ao teste do Campo Aberto, da Caixa Claro-Escuro e Suspensão pela Cauda, nesta ordem, com um intervalo de 30 minutos entre eles. Os resultados indicaram que a seqüência de testes é adequada para a avaliação destas atividades com economia de tempo, animais e drogas

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The main objective of the presented study is the design of a analog multiplier-divider as integrant part of the type-reducer circuit of type-2 fuzzy controller chip. The proposed circuit is a multiplier/divider which operates in current mode, in the CMOS technology with a supply voltage of 1.8 V.The circuit simulation was performed in PSPICE software with simulation model provided by AMS (Austria Mikro Systems International) in CMOS technology 0.35μm

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Pós-graduação em Odontologia Restauradora - ICT

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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This paper presents a proposal for the automation of the camera calibration process, locating and measuring image points in coded targets with sub-pixel precision. This automatic technique helps minimize localization errors, regardless of camera orientation and image scale. To develop this technique, several types of coded targets were analyzed and the ARUCO type was chosen due to its simplicity, ability to represent up to 1024 different targets and availability of source code implemented with the OpenCV library. ARUCO targets were generated and two calibration sheets were assembled to be used for the acquisition of images for camera calibration. The developed software can locate targets in the acquired images and it automatically extracts the coordinates of the four corners with sub-pixel accuracy. Experiments were conducted with real data showing that the targets are correctly identified unless excessive noise or fragmentation occurs mainly in the outer target square. The results with the calibration of a low cost camera showed that the process works and that the measurement accuracy of the corners achieves sub-pixel precision.