Structure and thermal behavior of PMMA-polysilsesquioxane organic-inorganic hybrids

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Predictors of Beta-Blocker Intolerance and Mortality in Patients After Acute Coronary Syndrome

Purpose: To investigate the predictors of intolerance to beta-blockers treatment and the 6-month mortality in hospitalized patients with acute coronary syndrome (ACS).Methods: This was a single-center, prospective, and longitudinal study including 370 consecutive ACS patients in Killip class I or II. BBs were prescribed according to international guidelines and withdrawn if intolerance occurred. The study was approved by the institutional ethics committee of our university. Statistics: the clinical parameters evaluated at admission, and the related intolerance to BBs and death at 6 months were analyzed using logistic regression (p<0.05) in PATIENTS.Results: BB intolerance was observed in 84 patients and was associated with no prior use of statins (OR: 2.16, 95%CI: 1.26-3.69, p= 0.005) and Killip class II (OR: 2.5, 95%CI: 1.30-4.75, p=0.004) in the model adjusted for age, sex, blood pressure, and renal function. There was no association with ST-segment alteration or left anterior descending coronary artery plaque. Intolerance to BB was associated with the greatest risk of death (OR: 4.5, 95%CI: 2.15-9.40, p<0.001).Conclusions: After ACS, intolerance to BBs in the first 48 h of admission was associated to non previous use of statin and Killip class II and had a high risk of death within 6 months.

Light-curing Time and Aging Effects on the Nanomechanical Properties of Methacrylate- and Silorane-based Restorations

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise tridimensional das alterações dento-alveolares em molares superiores após o uso do aparelho de Herbst

Pós-graduação em Ciências Odontológicas - FOAR

Estudo da infiltração marginal em restaurações de resinas compostas para dentes posteriores: efeito de material, preparo cavitário e condicionamento do esmalte a nível cervical

Pós-graduação em Odontologia Restauradora - ICT

Estudo da associaçao entre o Padrão face longa, o hábito de respiração bucal e as características intrabucais

Aim: to evaluate the association of the long face pattern and the mouth breathing, correlating them with the intraoral characteristics. Methods: the sample was composed of 60 Caucasian Brazilian descendents patients, divided in two groups according to the subjective of their facial pattern. The patients were clinically evaluated to determine their respiratory pattern and the diagnosed of malocclusion. The lateral teleradiographies were drawn in standard to verification facial cephalometric pattern. Chi-Square analysis evaluated the association between subjective facial pattern and type of breathing; facial pattern subjective and cephalometric facial pattern. It was also the chi-square with yates correction to evaluate the associations between subjective facial pattern, type of breathing and posterior cross bite; facial subjective standard, type of breathing and anterior open bite; facial pattern between subjective, type breathing and type of Angle´s malocclusion. Results: it showed that long face pattern (group 1) was associated with mouth breathing habit and facial cephalometric standard. Moreover, the long-face pattern (group 1) presented that mouth breathing was associated with a posterior crossbite and Angle Class II malocclusion. Conclusion: the long face pattern - evaluated with subjective facial analyses - was associated with mouth breathing. The long face pattern and patients with mouth breathing was associated with a posterior crossbite and Class II Angle's malocclusion.

Molecular and phylogenetic characterization based on the complete genome of a virulent pathotype of Newcastle disease virus isolated in the 1970s in Brazil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Effect of thermo-mechanical load cycling on silorane-based composite restorations

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da prevalência do tipo de crescimento crânio facial nas diferentes más oclusões, de acordo com a classificação de angle

During the orthodontic correction planning in addition to dental-jaw correction, facial aesthetics is the orthodontist's and patient's major concern. To prevent facial aesthetics damage is really important to take into account the type of craniofacial growth: mesofacial (balanced), dolichofacial (vertical) or brachyfacial (horizontal). We evaluated 152 documentation files from the Department of Orthodontics of Dental University of Sao Jose dos Campos- UNESP in order to analyze what kind of growth occurs in most Class I malocclusions, Class II and Class III Angle of treated individuals from 6 to 12 years old. From the randomly collected samples, 15 of them belonged to Class I Angle malocclusions; 123 belonged to Angle Class II and 14 to Class III malocclusion. The results showed that in Class I, 66.67% were classified as dolicocephalic; in Class II, 64.23% were classified as dolicocephalic and in Class III, 50% were brachycephalic. We conclude that the dolichofacial was the type which ocurred the most, both in females and males and both in malocclusion Class I and Class II. The brachyfacial type most occurred in Class III malocclusion and the mesofacial type occurred in smaller numbers in the three malocclusions studied

Lactato sanguíneo em cães com insuficiência cardíaca congestiva decorrente de degeneração valvular mitral

Pós-graduação em Medicina Veterinária - FCAV

Discovery of a new antiviral protein isolated Lonomia obliqua analysed by bioinformatics and real-time approaches

This study presents a new recombinant protein that acts as a powerful antiviral (rAVLO—recombinant Antiviral protein of Lonomia obliqua). It was able to reduce the replication by 106 fold for herpes virus and by 104 fold for rubella virus. RT-PCR of viral RNA rAVLO treated infected cells also showed similar rate of inhibition in replication. The analysis of this protein by bioinformatics suggests that this protein is globular, secreted with a signal peptide and has the ability to bind to MHC class I. It was found that there are several protein binding sites with various HLA and a prevalence of α-helices in the N-terminal region (overall classified as a α/β protein type). BLAST similarity sequence search for corresponding cDNA did not reveal a similar sequence in Genbank, suggesting that it is from a novel protein family. In this study we have observed that this recombinant protein and hemolymph has a potent antiviral action. This protein was produced in a baculovirus/Sf-9 system. Therefore, these analyses suggest that this novel polypeptide is a candidate as a broad spectrum antiviral.

Avalição ecocardiográfica do ventrículo direito e da pressão arterial pulmonar em portadoresde hipertireoidismo

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Diagnóstico da qualidade da água da microbacia do Córrego da Aldeia em Fernandópolis-SP

Pós-graduação em Engenharia Civil - FEIS

Efectos de los aparatos propulsores mandibulares fijos en la articulación temporomandibular

Fixed mandibular propulsion appliances are an alternative for the treatment of Class II malocclusion in individuals with mandibular deficiency. Since they are fixed appliances, said devices keep the mandible in an anterior-forced position during rest and during all mandibular functions. When a propulsive appliance is used, the lower jaw is displaced forward and downward. This movement leads to a new position of the condyle, which can, ultimately affect the normal functioning of the temporomandibular joint (TMJ). The aim of this paper was to review effects of fixed mandibular propulsive appliance on TMJ. Inclusion criteria considered studies on animals or humans using TMJ radiography, computed tomography, and magnetic resonance imaging. Studies confirm a favorable relation between condyle and glenoid fossa following treatment with fixed mandibular propulsion appliances.

Longitudinal study on skeletal changes during and after bionator therapy using metallic implants

Aim: To demonstrate the magnitude and direction of skeletal changes in the maxilla and mandible during and after the use of bionator, as well as their rotations. Methods: Partial superimposition on the maxilla and mandible on the metallic implants and total superimposition on the cranial base were performed at three periods, T1 before bionator therapy, T2 after bionator therapy, and T3 5.68 years after T2. Results: There was total clockwise maxillary rotation and counterclockwise mandibular rotation, in the North American technique, throughout the study period, as well as extensive remodeling on the condylar region, especially in vertical direction and on the gonial region in horizontal direction. Conclusions: The total maxillary rotation seemed to be significantly affected by therapy than the mandible. There was a clear change in the direction of condylar remodeling compared to the period of bionator therapy and posterior bionator therapy. Considering the entire study period, it was observed that intra-matrix rotation of the maxilla and mandible masked their total rotation, causing minimum changes in the matrix rotation.