Design and analysis of a multilayer localized surface plasmon resonance graphene biosensor

This paper describes a multilayer localized surface plasmon resonance (LSPR) graphene biosensor that includes a layer of graphene sheet on top of the gold layer, and the use of different coupled configuration of a laser beam. The study also investigates the enhancement of the sensitivity and detection accuracy of the biosensor through monitoring biomolecular interactions of biotin-streptavidin with the graphene layer on the gold thin film. Additionally, the role of thin films of gold, silver, copper and aluminum in the performance of the biosensor is separately investigated for monitoring the binding of streptavidin to the biotin groups. The performance of the LSPR graphene biosensor is theoretically and numerically assessed in terms of sensitivity, adsorption efficiency, and detection accuracy under varying conditions, including the thickness of biomolecule layer, number of graphene layers and operating wavelength. Enhanced sensitivity and improved adsorption efficiency are obtained for the LSPR graphene biosensor in comparison with its conventional counterpart; however, detection accuracy under the same resonance condition is reduced by 5.2% with a single graphene sheet. This reduction in detection accuracy (signal to noise ratio) can be compensated for by introducing an additional layer of silica doped B2O3 (sdB2O3) placed under the graphene layer. The role of prism configuration, prism angle and the interface medium (air and water) is also analyzed and it is found that the LSPR graphene biosensor has better sensitivity with triangular prism, higher prism angle, lower operating wavelength and larger number of graphene layers. The approach involves a plot of a reflectivity curve as a function of the incidence angle. The outcomes of this investigation highlight the ideal functioning condition corresponding to the best design parameters.

Sensitivity analysis of a sub-wavelength localized surface plasmon resonance graphene biosensor

Localized surface plasmon resonance (LSPR) is a promising detection method for label-free sensing of biomolecules. In this paper, a multilayer design for a LSPR biosensor is presented. In the proposed design, a periodic array of dielectric grating is incorporated on top of a graphene layer in the biosensor. The aim is to improve sensitivity of the LSPR biosensor through monitoring biomolecular interactions of biotin-streptavidin. Sensitivity improvement is obtained for the proposed LSPR biosensor compared with conventional SPR counterparts. In addition, to optimize the design, we have investigated grating geometry including volume factor and grating depth. The outcome of this investigation identifies ideal functioning conditions corresponding to the best design parameters.

Motivation-based IS evaluation strategy : a perspective of marketing information systems

The article describes the importance of motivational factors through an analysis of the core TAM constructs in the context of marketing IS evaluation. We argue that our findings compliment current IS evaluation strategy, specially for measuring motivational elements for online IS. The study consequently provides an empirical validation of the importance of motivational and behavioural factors. Through an experimental analysis we evaluated the relative importance of perceived enjoyment with perceived usefulness of using an online website for shopping purposes and found that enjoyment was by far the dominant predictor of attitude towards online shopping. The result illustrates that in terms of IS evaluation online environments have moved from being functional online applications to being functional, engaging and interactive online IS (e.g. websites).

The teacher’s role in promoting online peer group learning

Teachers have a major responsibility to engage students online for successful learning in online distance education programs. Identifying key aspects of the teachers’ role is important. The study reported in this paper investigated an online course for paramedic students. Data were collected from the teachers and students and their online interactions were observed. The study has shown that students’ message posting is likely to be related to the cognitive demand and accessibility of discussion tasks that staff design and the quality of teacher facilitation of discussion.

Online peer mentoring with pre-service teachers : a learning experience

In 2010, 34 pre-service teachers at Deakin University were invited to use Web 2.0 technologies to support practicum in rural and regional schools. Students in their final year of the Bachelor of Education Primary course were given access to an online forum, a ‗ning‘, to facilitate development of mentoring relationships within a community of peers. Access to the ning was presented as an optional extra available only to students undertaking their professional experience in rural and regional settings. Based on the work of Le Cornu (2005), mentoring was framed as a collaborative and collegial arrangement through which participants could hone the interpersonal and critical reflection skills crucial to practicum. A ning was selected as it: 1) allowed the creation of a closed, protected social network with customised options, and 2) requires little technological skills and investment of time from participants in terms of setting up a profile and participating in the online community. These features seemed to make it an ideal platform for pre-service teachers to analyse and reflect on professional experience. However, the small pre-service cohort did not choose to access the site. This unexpected outcome seems to challenge contemporary discourses about the current generation‘s attitudes to web based technology. It also highlights the importance of coupling use of template-based online tools, such as the ning, with awareness of Bourdieu‘s (1977) social capital to ensure uptake. In capturing the learnings from the project and systematically reviewing relevant literature, this paper provides a set of recommendations for conceptualising and engaging pre-service teachers in the use of online forums.

Religion and post-disaster development

This chapter discusses the role religion and religious organizations can play in development following a natural disaster. The development efforts in Aceh, Indonesia, following the Indian Ocean tsunami in 2004 provide examples of how the nature of Acehnese society, its views on religion, the role of religious organizations in the region, and the activities of aid agencies at the time all contributed the the post-disaster experience in this society.The chapter also considers what the role of faith in such situations might mean for future development efforts, especially in the context of natural disaster.

The Edinburgh companion to the history of democracy

Democracy has never been more popular. It is successfully practiced today in a myriad of different ways by people across virtually every cultural, religious or socio-economic context. The 45 original essays collected in this companion suggest that the global popularity of democracy derives in part from its breadth and depth in the common history of human civilization. It sets a benchmark as the first collection on the history of democracy to present lesser known examples, such as those of ancient China, medieval Islam, colonial Africa or today's Burma, alongside more familiar cases like Athens, the English Parliament, the French Revolution and Women's Suffrage.

Undersdtanding where democracy comes from, and where its greatest successes and most dismal failures lie, is central to democracy's project of inventing ways to address the need of people everywhere to live in peace and freedom and with a say in the decisions that affect their lives.

A S-parameters-based detection method for a multilayer SPR biosensor

In this paper, S-parameters investigation of a variable incidence angle multilayer SPR biosensor is presented. Both magnitude and phase of the S-parameters are taken into account in the investigation. The work presented in this paper is the first attempt to apply S-parameters analysis to a multilayer SPR biosensor. The goal is to improve sensitivity through involving S-parameters including their phase values. In addition, further investigation is carried out to understand the relationship between the S-parameters and thickness of biomolecular layer and also the design parameters including the number of graphene layers.

Design and analysis of a multilayer surface plasmon resonance biosensor

Designed a multilayer SPR biosensor to improve the detection sensitivity and accuracy simultaneously. Developed a design procedure to identify optimum design parameters for SPR biosensing. Devised a new detection measurement technique based on S-parameters for SPR biosensing.

Breastfeeding and infant sleep patterns : an Australian population study

Objective : Our purpose was to determine if babies breastfed at 6 months of age were more likely to wake at night and less likely to sleep alone than formula-fed babies.

Patients and Methods : Data were drawn from the first wave of The Longitudinal Study of Australian Children, an ongoing, nationally representative study of the growth and development of Australia's children. The 4507 participants met the criteria for this study. The measures examined infant sleep problems as the outcome and breastfeeding at 6 months of age as the exposure in addition to the demographic data, maternal mental health, infant birthweight and gestational age at delivery.

Results : After adjustment for covariates, reports by mothers of infants that breastfed at 6 months of age suggested infants were 66% more likely to wake during the night and 72% more likely to report difficulty sleeping alone. However, breastfeeding had a strongly protective effect on wheezing, coughing, snoring and breathing problems, and it was not associated with restless sleep or problems getting to sleep for the infant.

Conclusions : Breastfeeding was found to be associated with increased night waking and this is consistent with other studies. There are biological reasons why this might be required to ensure breastfeeding continues to 6 months and beyond. The current low rates of sustained breastfeeding in many Western countries needs to be reconsidered in relation to parental and public health practices promoting prolonged nocturnal infant sleep patterns.

Workplace human rights reporting: a study of Australian garment and retail companies

The opening of the Australian economy in a globalised world has led to Australian garment and retail corporations moving their manufacturing overseas and acquiring goods from overseas providers. This is usually better for the corporations’ bottom-line, as they can purchase goods overseas at a fraction of their local cost, partly due to cheap labour. Australia is one of the many OECD countries not to have a well regulated environment for workplace human rights. This study examines 18 major Australian retail and garment manufacturing corporations and finds that workplace human rights reporting is poor, based on content analysis of their annual reports, corporate social responsibility reports and websites. This is probably due to the failure of the Australian Government to provide adequate oversight by promulgating mandatory reporting standards for both local and overseas operations of Australian companies. This permits corporations to avoid reporting their workplace human rights standards and breaches.