Frequency of CCR5 Delta-32 Mutation in Human Immunodeficiency Virus (HIV)-seropositive and HIV-exposed Seronegative Individuals and in General Population of Medellin, Colombia

Repeated exposure to human immunodeficiency virus (HIV) does not always result in seroconversion. Modifications in coreceptors for HIV entrance to target cells are one of the factors that block the infection. We studied the frequency of Delta-32 mutation in ccr5 gene in Medellin, Colombia. Two hundred and eighteen individuals distributed in three different groups were analyzed for Delta-32 mutation in ccr5 gene by polymerase chain reaction (PCR): 29 HIV seropositive (SP), 39 exposed seronegative (ESN) and 150 individuals as a general population sample (GPS). The frequency of the Delta-32 mutant allele was 3.8% for ESN, 2.7% for GPS and 1.7% for SP. Only one homozygous mutant genotype (Delta-32/Delta-32) was found among the ESN (2.6%). The heterozygous genotype (ccr5/Delta-32) was found in eight GPS (5.3%), in one SP (3.4%) and in one ESN (2.6%). The differences in the allelic and genotypic frequencies among the three groups were not statistically significant. A comparison between the expected and the observed genotypic frequencies showed that these frequencies were significantly different for the ESN group, which indirectly suggests a protective effect of the mutant genotype (Delta-32/Delta-32). Since this mutant genotype explained the resistance of infection in only one of our ESN persons, different mechanisms of protection must be playing a more important role in this population.

Análisis de la dimensión ambiental de la tenencia de la tierra. El caso de la Zona Protectora y Parque Nacional Volcán Tenorio de Costa Rica

El presente estudio consiste en la elaboración de un mapa del estado de tenencia de la tierra actual de la Zona Protectora y Parque Nacional Volcán Tenorio situado al norte de Costa Rica. A partir de este resultado cartográfico se efectuarán estudios referentes al estado legal de las propiedades, al tipo de propiedad, a la ubicación de las propiedades dentro del Área Silvestre Protegida y al evalúo de los conflictos legales dentro de ésta. Por otro lado, se analiza la cobertura de la tierra y el estado de conservación. La metodología utilizada se basa en el uso de Sistemas de Información Geográfica y en la verificación de la información mediante puntos GPS tomados al campo y su análisis en la oficina. Los resultados muestran una reubicación de los planos más precisa y real que la indicada por el Catastro Nacional. Aunque las propiedades privadas son mayoritarias, el área de estudio presenta en general un porcentaje alto de masa boscosa, mientras que en las zonas limítrofes se encuentra una fragmentación del hábitat determinada por herbazales. Este estudio contribuye a una mejor gestión y conservación del Área Protegida y es un avance en el ordenamiento territorial del país.

GP Fundholding VFM Study Summary Report (PDF 1932 KB)

November 1999 - covering Management arrangments for GP Fundholding, GP Fundholder Achievements and Involving GPs in Commissioning

Methadone maintenance treatment (MMT) in general practice or in specialized centers: profile of patients in the Swiss Canton of Vaud.

We studied profile of patients (n=1782) treated in specialized centers and general practice (GP) enrolled in methadone maintenance treatment (MMT) programs during 2001 in the Swiss Canton of Vaud. We found that GPs treated the majority of patients (76%). Specialized centers treated a higher proportion of patients with uncontrolled intravenous use of cocaine and heroin, and prescribed neuroleptics as concomitant medication three times more frequently than GPs. Patients treated in specialized centers were more likely to undergo screening for HIV, HBV, HCV, and receive complete HBV immunization. In conclusion, specialized centers are more likely to treat severely addicted patients and patients with a poor global assessment (physical, psychiatric, and social).

Framework Agreement between the Minister for Health and the Irish Medical Organisation in respect of a process for engagement concerning the GMS/GP Contract

Minister of State with responsibility for Primary Care, Alex White TD, today (4 June 2014) concluded a series of meetings with the Irish Medical Organisation (IMO) with the signing of the Framework Agreement between the Minister of Health, the HSE and the Irish Medical Organisation (IMO) setting out a process for engagement concerning the GMS/GP contract and other publicly funded contracts involving General Practitioners (GPs). Download document here

The Healthy Weight Challenge

To help encourage, facilitate and empower people to adopt healthy lifestyles and to raise awareness of obesity and its causes in order to reduce its prevalence within the target community. Outcome Through Health Classes, Leaflets and Posters, people have developed their knowledge and understanding of obesity. The relationship between members of the community and the pharmacist has also developed as as has the Pharmacists links with GPs, Dieticians, Leisure Centre Management etcï_… All participants thought the healthy weight challenge was a good idea, made them more aware of health and the pharmacy was able to offer advice, information, support and health checks. regular monitoring also helped have a positive impact on participants desire to lose weight and also had positive impact on their efforts to have healthier lifestyle.

Rural Health Partnership

This is their 3rd BCPP project and this is a Level 3 project. Rural Health Partnership is a community based initiative which assists people to recover from a mental illness. Previous BCPP projects focussed on supporting the needs of women in relation to mental health and more specifically, those experiencing post natal depression through the 2nd BCPP project using a lay health approach. This project seeks to build on this previous work. A very good working relationship has developed between the pharmacist and RHP. A programme of activities that can enhance the skills and knowledge base of the participants will be developed and so will relationships with other services eg GPs, primary care team etc. The project aims to educate the community at large on the issues faced by vulnerable women, with particular emphasis on symptoms of postnatal depression and anxiety.

GeoTools-Android : herramientas geográficas para Android

Este trabajo pretende esbozar el estado del arte en cuanto a herramientas geoespaciales desarrolladas para el sistema operativo Android, encontrado en muchos dispositivos "smartphone" actuales. Se centra en los navegadores de mapas, como aplicación más representativa de este tipo de herramientas. Se destaca el papel de la empresa Google Inc. como desarrollador de la plataforma y principal proveedor web de información geográfica, y se exploran algunas alternativas.

Realitat augmentada per Android a la Vall d'Incles

En aquest treball s'exposa un petit estudi de la tecnologia Android, també es fa un anàlisi de la realitat augmentada i del framework LookAR. Es comença amb una visió general del funcionament d'Android, es repassa el concepte de realitat augmentada i s'analitzen diferents eines de treball per RA. Es fa una descripció del funcionament de LookAR i s'analitzen les eines per a mapes GoogleMaps i OpenstreetMaps. Finalment es realitza una aplicació en Android amb quatres funcionalitats. Una funció de càmera de realitat augmentada amb el framework Lookar, una funció de GoogleMaps per mostrar la nostra ubicació en un mapa, una altre funció per mostrar la localització via GPS o WIFI i finalment una funció per mostrar una llista de diferents punts d'interès que s'utilitzaran per mostrar informació sobre el mapa i en la càmera de realitat augmentada.

The pregnancy book

This book provides information on many aspects of pregnancy and a list of useful organisations. It is available to first time expectant mothers through primary care services (antenatal clinics, GPs or health visitors).

Realitat augmentada per Android a la ciutat de Palma de Mallorca (RAPAMA)

Aquest projecte de final de carrera (PFC) consisteix en l'estudi, anàlisi, disseny i implementació d'un sistema de realitat augmentada (RA) que permet localitzar les aturades dels serveis de transport públic de la ciutat, així com detectar les més properes a la ubicació actual de l'usuari. Per aquest projecte s'ha desenvolupat una aplicació Android amb el framework LookAR que permet detectar la posició i orientació del dispositiu i informarà de les aturades es troben més a prop. Per això es fa servir informació georeferenciada de les aturades que s'emmagatzemen en una base de dades i es far el tractament necessari per posicionar-les. Per altra banda, s'utilitzen el GPS i giroscopi o brúixola digital, per conèixer la orientació i d'aquesta manera poder indicar i representar gràficament la informació que es té emmagatzemada a la base de dades espacial. L'accés a la informació espacial per part de l'aplicació, no és directe, sinó que es realitza a través d'un servei web desenvolupat segons els estàndards.

Birth to five

This book provides information on caring for children up to five years old and contact details for useful organisations. It is available to new parents through primary care services (antenatal clinics, GPs or health visitors).