Influence of age and DNA damage on expression of damage-processing genes

The effect of DNA damaging agents and age on expression of damage-processing genes was examined in plants and mice. Treatment with these agents increased expression of some genes. The effect of gene expression in the absence of treatment decreased with age, suggesting links between ageing and genetic instability.

Internet child pornography : an examination of attachment and intimacy deficits

This study found that Internet child pornographers (ICP) reported significantly less optimal attachment than non-offenders, matched child and matched adult sexual offenders. ICP also reported a more negative view of self than non-offenders and the matched sexual offender groups. Finally, the ICP group reported more social avoidance and distress than non-offenders. The portfolio explores the influence of treatment readiness on the best practice principles when working with violent offenders in relation to their assessment, and subsequent treatment recommendations. The importance of treatment readiness and its utility in relation to these principles is highlighted in four case studies.

An exploratory study of the factors that influence physical activity for prostate cancer survivors

Purpose To gain an understanding of the factors that influence participation in physical activity for survivors of prostate cancer and to examine changes in participation in physical activity pre- and post-diagnosis.
Methods Eighteen men who had completed treatment for prostate cancer 6 months prior were interviewed for this study. Constant comparison was used to examine the main themes arising from the interviews.
Results Barriers to physical activity tended not to be related to the physical side effects of treatment, however lack of confidence following treatment, co-morbidities, older age physical decline and lack of time were barriers. Motivations for physical activity included psychological benefits, physical benefits, and the context of the activity. Participants did not recall receiving information about physical activity from clinicians and few were referred to exercise specialists. Physical activity 6 months post-treatment was similar to physical activity levels prior to diagnosis, although there was some decline in terms of the intensity of participation.
Conclusions Interventions to increase physical activity for this group will need to take into account co-morbidities and decline associated with older age, as well as treatment side effects and psychological issues associated with a cancer diagnosis. Encouragement from health care professionals
and referral to an exercise specialist is likely to give men more confidence to participate in physical activity.