An ecological characterization of Coastal Maine (north and east of Cape Elizabeth) / Stewart I. Fefer and Patricia S. Schettig: principal investigators.

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Effects of Genome Position and the DNA Damage Checkpoint on the Structure and Frequency of sod2 Gene Amplification in Fission Yeast

The Schizosaccharomyces pombe sod2 gene, located near the telomere on the long arm of chromosome I, encodes a Na+ (or Li+)/H+ antiporter. Amplification of sod2 has previously been shown to confer resistance to LiCl. We analyzed 20 independent LiCl-resistant strains and found that the only observed mechanism of resistance is amplification of sod2. The amplicons are linear, extrachromosomal elements either 225 or 180 kb long, containing both sod2 and telomere sequences. To determine whether proximity to a telomere is necessary for sod2 amplification, a strain was constructed in which the gene was moved to the middle of the same chromosomal arm. Selection of LiCl-resistant strains in this genetic background also yielded amplifications of sod2, but in this case the amplified DNA was exclusively chromosomal. Thus, proximity to a telomere is not a prerequisite for gene amplification in S. pombe but does affect the mechanism. Relative to wild-type cells, mutants with defects in the DNA damage aspect of the rad checkpoint control pathway had an increased frequency of sod2 amplification, whereas mutants defective in the S-phase completion checkpoint did not. Two models for generating the amplified DNA are presented.

As limitações ao exercício da Reforma Constitucional e a dupla revisão / Maria Elizabeth Guimarães Teixeira Rocha. --

Trabalho apresentado ao professor Jorge Miranda, na Universidade Católica Portuguesa, em outubro de 1989.

A intervenção do Estado brasileiro e a política oligárquica na República Velha / Maria Elizabeth Guimarães Teixeira Rocha. --

Trabalho apresentado na disciplina direito econômico I, no curso de doutorado em direito constitucional na Universidadae Federal de Minas Gerais.

A Justiça Militar da União na Constituição brasileira de 1988 / Maria Elizabeth Guimarães Teixeira Rocha.

"Edição especial em comemoração aos vinte anos de promulgação da Constituição de 1988".

A Transdiagnostic Social Skills Intervention; Using a Structured Story to Teach Children How to Ask a Friend to Play

An (independent samples comparison) controlled study was conducted to assess the efficacy of a novel approach to social skills training for children in a local socialization group at Knippenberg, Patterson & Associates (KPA). The treatment condition involved the combination of a Structured Story (i.e., novel bibliotherapy technique for children with social skills deficits), and a behavioral rehearsal (or role-play) segment, where the children practiced the target social skill featured in the Structure Story. The control group did not receive the Structured Story nor the behavioral rehearsal. Children in both groups engaged in ten-minutes of free play that was videorecorded for later observation and scoring by the principal investigator. Two target behaviors were assessed; asking a friend to play, and duration of joint play between two or more peers. The results did not show significant differences for either target variable between the group that received the novel intervention and the control group. Limitations of the current study and implications for further research are discussed.

Gauger's certificate, 1785 September 10

One-page handwritten document certifying Caleb Hayden was taught the art of gauging.

Will of the Rev. Andrew Croswell, 1785 November

This folder contains three handwritten copies of the November 8, 1785, will of Andrew Croswell and a copy of the inventory of Croswell's estate.

Accounts with Benjamin Huntington, 1785-1787

This folder contains two handwritten copies of the accounts between Reverend Andrew Croswell of Boston, and Croswell's executor William Croswell, and Benjamin Huntington, for money collected from Col. Gallup between 1785 and 1787.

Receipts related to the dispersal of the Croswell estate, 1785-1788

Seven handwritten receipts dated between 1785 and 1788.

Financial bills and receipts, 1785-1786

This folder contains eight bills and receipts including five receipts for payment by William Croswell for the costs of boarding Croswell's brother Nathaniel.