Operator's manual : truck tractor, line haul, 50,000 GVWR, 6 x 4, M915 (NSN 2320-01-028-4395), truck tractor, light equipment transporter (LET), 56,000 GVWR, 6 x 6, w/winch, M916 (NSN 2320-01-028-4396), truck tractor, medium equipment transporter (MET), 75,000 GVWH, 8 x 6, w/winch, M920 (NSN 2320-01-028-4397) ....

Includes index.

Direct support and general maintenance : truck tractor, line haul, 50,000 GVWR, 6 X 4, M915A1, (NSN 2320-01-125-2640).

"December 1983"--Vol. 1.

Organizational maintenance : truck tractor, line haul, 50,000 GVWR, 6 x 4, M915A1 (NSN 2320-01-125-2640).

"December 1983."

Organizational maintenance : truck tractor, line haul, 50,000 GVWR, 6 x 4, M915A1 (NSN 2320-01-125-2640).

"December 1983"--Vol. 2.

Operator's manual : truck tractor, line haul, 50,000 GVWR, 6 x 4, M915 (NSN 2320-01-028-4395), truck tractor, light equipment transporter (LET), 56,000 GVWR, 6 x 6, w/winch, M916 (NSN 2320-01-028-4396), truck tractor, medium equipment transporter (MET), 75,000 GVWR, 8 x 6, w/winch, M920 (NSN 2320-01-028-4397) ....

"May 1980."

Operator's manual [microform] : truck tractor, line haul, 50,000 GVWR, 6 x 4, M915 (NSN 2320-01-028-4396), truck tractor, light equipment transporter (let), 56,000 CVWR, 6 x 6, w/winch, M916 (NSN 2320-01-028-4396), truck tractor, medium equipment transporter (met), 75,000 GVWR, 8 x 6, w/winch, M920 (NSN 2320-01-028-4397) : truck chassis, 75,000 BVWR, 8 x 6 for 20 ton dump truck, M917 (NSN 3806-01-028-4389), truck chassis, 56,000 GVWR, 6 x 8, for bituminous distributor truck, M918 (NSN 3805-01-028-4390), truck chassis, 75,000 GVWR, 8 x 6, for concrete mobile mixer truck, M819 (NSN 3856-01-4391).

"May 1980."

Direct support and general support maintenance repair parts and special tools lists : truck, dump, 20 ton, 6 x 4, on-off highway, 71,000 GVW (NSN 3805-00-192-7249), IHC model F-5070 (CCE).

"March 1992."

Combined operation and maintenance instructions : organizational and intermediate : radio terminal set AN/TRC-17017(V)3, part number 951100-5, NSN 5820-01-148-3976.

"1 August 1985."

Dan jing zhai shi wen chao : wen chao 6 juan, wai pian 2 juan, shi chao 6 juan /

Zi Ruigu deng chong jiao kan ben.

Oxberry's Dramatic biography and histrionic anecdotes.

Nos. 4-5 in a volume of pamphlets. Includes memoirs of Edmund Kean, Charles Young, and Mrs. Harriett Coutts.

Betonung; Metrik; Einzel-Beispiele; Psalm 1 bis 6; Exodus 15; Deborahlied, Lied der Sulamith

Aus der Sammlung des Leo Baeck Institute, digitalisiert in Kooperation mit dem Center for Jewish History, NY

Papillomavirus virus-like particles activate the PI3-kinase pathway via alpha-6 beta-4 integrin upon binding

We have previously shown that human papillomavirus virus-like particles (VLPs) are able to activate the Ras/MAP kinase pathway. Ras can also elicit an anti-apoptotic signal via PI3-kinase so we investigated this further. Here we show that binding of VLPs from HPV types 6b, 18, 3 1, 35 and BPV1 results in activation of PI3-kinase. Activation was achieved by either L1 or L1/L2 VLPs and was dependent on both VLP-cell interaction and correct conformation of the virus particle. VLP-induced PI3-kinase activity resulted in efficient downstream signaling to Akt and consequent phosphorylation of FKHR and GSK3 beta. We also present evidence that PV signaling is activated via the alpha 6 beta 4 integrin. These data suggest that papillomaviruses use a common receptor that is able to signal through to Ras. Combined activation of the Ras/MAP kinase and PI3-kinase pathways may be beneficial for the virus by increasing cell numbers and producing an environment more conducive to infection. (c) 2006 Elsevier Inc. All rights reserved

Cleavage of caspases-1, -3, -6, -8 and -9 substrates by proteases in skeletal muscles from mice undergoing cancer cachexia

A prominent feature of several type of cancer is cachexia. This syndrome causes a marked loss of lean body mass and muscle wasting, and appears to be mediated by cytokines and tumour products. There are several proteases and proteolytic pathways that could be responsible for the protein breakdown. In the present study, we investigated whether caspases are involved in the proteolytic process of skeletal muscle catabolism observed in a murine model of cancer cachexia (MAC16), in comparison with a related tumour (MAC13), which does not induce cachexia. Using specific peptide substrates, there was an increase of 54% in the proteolytic activity of caspase-1, 84% of caspase-8, 98% of caspase-3 151% to caspase-6 and 177% of caspase-9, in the gastrocnemius muscle of animals bearing the MAC16 tumour (up to 25% weight loss), in relation to muscle from animals bearing the MAC13 tumour (1-5% weight loss). The dual pattern of 89 kDa and 25 kDa fragmentation of poly (ADP-ribose) polymerase (PARP) occurred in the muscle samples from animals bearing the MAC16 tumour and with a high amount of caspase-like activity. Cytochrome c was present in the cytosolic fractions of gastrocnemius muscles from both groups of animals, suggesting that cytochrome c release from mitochondria may be involved in caspase activation. There was no evidence for DNA fragmentation into a nucleosomal ladder typical of apoptosis in the muscles of either group of mice. This data supports a role for caspases in the catabolic events in muscle involved in the cancer cachexia syndrome. © 2001 Cancer Research Campaign.