Audit report on the Iowa Department of Human Services – Case Management Unit for the year ended June 30, 2006

Audit report on the Iowa Department of Human Services – Case Management Unit for the year ended June 30, 2006

Fiscal Year 2006 IOWAccess Revolving Fund Report. Administrative Services.

Legislatively Mandated Report. Iowa Code §8A.224 – “The department shall submit an annual report not later than January 31 to the members of the General Assembly and the Legislative Services Agency of the activities funded by and expenditures made from the revolving fund during the preceding fiscal year.

Audit report on the Iowa Department of Agriculture and Land Stewardship for the year ended June 30, 2006

Audit report on the Iowa Department of Agriculture and Land Stewardship for the year ended June 30, 2006

Fiscal Year 2008-2012 Iowa Transportation Improvement Program

This document was prepared by the Iowa Department of Transportation to inform Iowans of planned investments in the state's transportation system over the next five years.

Iowa Utilities Board Fiscal Year 2006 Regulatory Plan Pursuant to Executive Order Nine

Regulatory Plan for Fiscal Year 2005

Iowa Utilities Board Fiscal Year 2007 Regulatory Plan Pursuant to Executive Order Nine

Regulatory Plan for Fiscal Year 2007

Iowa Utilities Board Fiscal Year 2008 Regulatory Plan Pursuant to Executive Order Nine

Regulatory Plan for Fiscal Year 2008

Audit report on the Iowa Braille and Sight Saving School, Vinton, Iowa, for the year ended June 30, 2006

Audit report on the Iowa Braille and Sight Saving School, Vinton, Iowa, for the year ended June 30, 2006

Fatal case of Epstein-Barr virus primo-infection, haemophagocytic syndrome in a 26-year-old patient treated with azathioprine for Crohn's disease: an autopsy case

Objective: A 26-year-old man with a history of Crohn's disease, treated with azathioprine since 2 years, presented an Epstein-Barr virus (EBV) primo-infection and exacerbation of digestive symptoms. Method: An ileo-colectomy was performed, which showed a fatal EBV lymphoproliferation disorder along with a haemophagocytic syndrome. EBV DNA load in the peripheral blood persisted to be high loaded during hospitalisation (479,000 copies per milliliter) despite triple antiviral treatment. Results: Autopsy revealed a systemic lymphoproliferation involving lymph nodes, gastrointestinal mucosa and solid viscera (heart, kidney, lungs, prostate, brain). This was compounded of a population of large polymorphic B cell, hypertrophic macrophages and T lymphocytes, associated to haemophagocytosis. These massive infiltrations mimicked macroscopically as ulcers in the intestinal mucosa and ranged from polymorphic with plasmocytic differentiation to monomorphic large cells. Autopsy results confirmed the absence of Crohn's disease reactivation. The EBV infection was observed in all organs within the large images of the B cell lymphoproliferations. Further postmortem investigations revealed a deficit of the azathioprine's metabolisation enzyme thiopurine methyltransferase (TPMT). Conclusion: We report and discuss herein the observations of a complete autopsy case along with the postmortem identification of the EBV infection type and TPMT mutation in a patient treated by azathioprine for Crohn's disease. Autopsy findings and further investigations helped explain the complicate clinical evolution and the fatal issue of the patient.

Audit report on the Office of Secretary of State for the year ended June 30, 2006

Audit report on the Office of Secretary of State for the year ended June 30, 2006

Audit report on the Iowa Department of Workforce Development for the year ended June 30, 2006

Audit report on the Iowa Department of Workforce Development for the year ended June 30, 2006

Year 3 Accomplishments, 2003

Water fact sheet for Iowa Department of Natural Resources and the Geological Bureau.

Year 4 Accomplishments, 2004

Water fact sheet for Iowa Department of Natural Resources and the Geological Bureau.

Report of Recommendations to the Board of Regents for the year ended June 30, 2006

Report of Recommendations to the Board of Regents for the year ended June 30, 2006

Audit report on the Iowa Department of Public Safety for the year ended June 30, 2006

Audit report on the Iowa Department of Public Safety for the year ended June 30, 2006