Assessing melatonin and its oxidative metabolites amounts in biological fluid and culture medium by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Light-curing Time and Aging Effects on the Nanomechanical Properties of Methacrylate- and Silorane-based Restorations

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relationships between oral infections and blood glucose concentrations or hba1c levels in normal and diabetic rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Clopidogrel enhances periodontal repair in rats through decreased inflammation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Bleaching effectiveness, hydrogen peroxide diffusion, and cytotoxicity of a chemically activated bleaching gel

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Headache Associated With Temporomandibular Disorders Among Young Brazilian Adolescents

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Light and temperature induce variations in the density and ultrastructure of the secretory spaces in the diesel-tree (Copaifera langsdorffii Desf.-Leguminosae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Natural Products from Cyanobacteria with Antimicrobial and Antitumor Activity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effect of menthol in experimentally induced ulcers: Pathways of gastroprotection

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ginkgo Biloba Extract in an Animal Model of Parkinson's Disease: A Systematic Review

Although the exact cause of neuronal loss in Parkinson's disease is not known, evidence points to oxidative stress and the production of reactive oxygen species as the main events that occur in the substantia nigra pars compacta of the brain of parkinsonians. EGb761 is an extract of the leaves from the Ginkgo biloba tree that has been reported as an antioxidant and neuroprotective agent. The objective of this work was to perform a systematic review of the studies that analysed the effect of Ginkgo biloba extract on Parkinson's disease or Parkinsonism. This research was conducted using the following databases: Medline, PsycInfo, Cinahl, Sigle, Lilacs, Scielo, Cochrane Library, and Embase. Initially, we selected 32 articles. After a more detailed analysis, only 10 articles remained. One of the hypotheses for the positive effect of EGb761 on Parkinson's disease is the reduction or inhibition of monoamine-oxidase activity. This enzyme metabolises dopamine, inducing the formation of free radicals, which in turn damage nigrostriatal neurons. Another hypothesis is that the neuroprotective effect of EGb761 against 6-hydroxydopamine, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and MPP+ toxins. As there are few studies on the effect of EGb761 on humans, this review could contribute new data to further the discussion of this issue.

Determinação da doçura ideal em néctar de mamão adicionado de açúcar

Papaya is a fruit whose pulp has attractive sensory, chemical and digestive characteristics, with high production in the country. Nevertheless, the nectar of this fruit is not widespread in the market. Thus, this study aimed to develop nectars of papaya with different sugar contents to adjust the sweetness to sugar ideal for this product. Four formulations of nectar of papaya were prepared with the same proportions of pulp and water, and sugar concentrations at 6, 8, 10 and 12%. One hundred untrained panelists participated to the affective test of acceptance by the just-about-right scale with nine categories, ranging from extremely less sweet than ideal to extremely sweeter than ideal. There was an increase in the percentage for the ideal sweetness as sugar concentration increased from 6 to 12%. There was also verified a predominance in the frequency of responses for the categories less sweet than ideal to nectar of papaya with 6% sugar and for the categories sweeter than ideal to nectar of papaya with 12% sugar. The sugar concentration must be 10.4% to obtain nectar papaya with ideal sweetness.

Phyllosphere Bacteria Improve Animal Contribution to Plant Nutrition

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Reformulation and a Lagrangian heuristic for lot sizing problem on parallel machines

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Copper(II) and Nickel (II) Complexation Capacity of Dissolved Organic Matter from Rivers of Agricultural and Urban Areas in the State of Sao Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Use of Chemometric Tools to Determine the Source of Metals in Sediments of the Rivers of the Turvo/Grande Hydrographical Basin, Sao Paulo State, Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)