Ensaios terap��uticos com penicilina V-Bouba (Framboesia, pian, yaws): I - Dose curatina m��nima: II - Redu����o do n��mero de inje����es diarias: III - Redu����o de tempo de tratamento pelo empr��go de doses mais elevadas

This report belongs to the series of works carried out Oswaldo Cruz Ins��titute, on the treatment of treponematosis with penicillin. The present report deals with investigations performed in order to ascer��tain the following points: 1) the mininal curative dosis for the initial lesions of yaws; 2) the effect of reduction of the number of injections each day, to verifie the possibility of application of penicillin in the prophylaxis of yaws in rural zones; 3) reduction of the time of treatment by application of high dosis. 1) With dosis of 150 and 100 Oxford units each four hours, clinical reco��very was obtained after 17 days of treatment. With 50 O.u. during 40 days clinical recovery was not obtained. 2) a) With 3 injections of 400 O.u. each day (6,12 and 18 ho��rs clocks) clinical recovery was obtained after 14 to 16 days; b) with 2 injections of 400 O.u. each day (6 and 18 hoors clocks), clinical recovery was obtained after 16 to 23 days; c) with 1 injection of 1.600 and 3.200 each day, clinical recovery was obtained after 30 and 20 days. 3) With dosis of 33.3 and 46.7 O.u. by each kilo of weight each four hours, during 15 days, clinical recovery was obtained more or less in 25 days. The same result was obtained with the dosis of 61.5 and 166.7 O.u. by each kilo of weight, each four hours, during 4 days. But with 100.000 O.u. in fine dosis of 20.000 in a day ou by, clinical recovery was not obtained.

As esp��cies neotropicais da fam��lia Simuliidae Schiner, 1864 (Diptera-Nematocera): I. Simulim (Eusimulium) orbitale Lutz, 1910, Simulium (Eusimulium) pintoi n. sp. e Simulium nigrimanum MACQUART, 1837, sp. inquirendae

Os AA. iniciam com o presente trabalho uma s��rie de publica����es com o fim de rever as esp��cies neotropicais da fam��lia Simuliidae. Fazem a revis��o bibliogr��fica, a redescri����o do macho, f��mea, pupa, larva, e elegem os ne��tipos de S. (E) orbitale LUTZ, 1910. Descrevem S. (E.) pintoi n. sp. de macho, f��mea, pupa e larva; consideram S. nigrimanum MACQ., 1837 como sp. inquirendae.

A vegeta����o no munic��pio de Ilh��us, Estado da Bahia: I - estudo sinecol��gico das ��reas de pesquisas s��bre a febre amarela silvestre realizado pelo S. E. P. F. A

I - Methods. II - Phytogeographic aspects. III - The communities and botanical associations: a) The lava P��s-Castelo Novo study area. b) The study area at the Pirataquiss�� farm. c) The Ribeir��o da Fortuna study area. IV - Conclusions.

Mixed Hodge structures and vector bundles on the projective Plane I

We describe an equivalence of categories between the category of mixed Hodge structures and a category of vector bundles on the toric complex projective plane which verify some semistability condition. We then apply this correspondence to define an invariant which generalises the notion of R-split mixed Hodge structure and compute extensions in the category of mixed Hodge structures in terms of extensions of the corresponding vector bundles. We also give a relative version of this correspondence and apply it to define stratifications of the bases of the variations of mixed Hodge structure.

I. New species of Cuban Senecioneae. II. Diagnoses of new species and notes on other spermatophytes, chiefly from Mexico and Central America. By Jesse More Greenman.

v.2:no.8(1912)

Verifica����es s��bre a incid��ncia de siclemia em ��ndios brasileiros: I- ��ndios Pariukur, Galiby, Caripuna, Canella e Carnij��

Em 671 ��ndios puros, de 7 tribus diferentes, n��o foi verificado o fen��meno de siclisa����o da hem��tia. No agrupamento de ��ndios Carnij�� ou fulni�� (Aguas Bellas), Estado de Pernambuco, em 166 indiv��duos, 3 eram sicl��micos (��ndice de sicl��micos 1,8%).Este agrupamento �� muito micigenado. Estas observa����es refor��am a utilidade do empr��go do teste de sicl��mia em Antropologia.