Receipt for Summer Term Upper Canada College

Receipt for the summer term at Upper Canada College. The term runs from April 21st to June 30th. Fees paid by H.K. Woodruff, 1878.

Letter to Messrs. Summer and Nelles of Grimsbyy from Thomas Street and Mr. Hamilton

Letter to Messrs. Summer and Nelles of Grimsby from Thomas Street and Mr. Hamilton in which they state that W.S. Britton has purchased the Grimsby Mills that belonged to W. James Paterson, Jan. 17, 1848.

Letter to Messrs. Summer and Nelles of Grimsby from T.A. Stayner

Letter to Messrs. Summer and Nelles of Grimsby from T.A. Stayner, Postmaster General stating that the accompanying letter [letter is not enclosed] has been returned to the writer on payment of postage. (1 page, printed). This letter is barely legible. Much of the text is missing, July 1848.

Letter to Mr. Summer and Mr. Nelles from the Office of the N.D. Mutual Insurance Company of St. Catharines

Letter to Mr. Summer and Mr. Nelles from the Office of the N.D. Mutual Insurance Company of St. Catharines regarding an assessment of 4 % on the premium notes of this company. This is signed by Mr. Arnold, secretary of N.D. Mutual F. Insurance Company, Aug. 9, 1848.

Rural life in America: or, summer and winter in the country

UANL

Constituting "Community" at the onset of the Pascua Lama Mining Project

Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal.

Early-onset and late-onset Alzheimer’s disease are associated with distinct patterns of memory impairment

The goal of this study was to investigate the specific patterns of memory breakdown in patients suffering from early-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease (LOAD). Twenty EOAD patients, twenty LOAD patients, twenty matched younger controls, and twenty matched older controls participated in this study. All participants underwent a detailed neuropsychological assessment, an MRI scan, an FDG-PET scan, and AD patients had biomarkers as supporting evidence of both amyloïdopathy and neuronal injury. Results of the neuropsychological assessment showed that both EOAD and LOAD groups were impaired in the domains of memory, executive functions, language, praxis, and visuoconstructional abilities, when compared to their respective control groups. EOAD and LOAD groups, however, showed distinct patterns of memory impairment. Even though both groups were similarly affected on measures of episodic, short term and working memory, in contrast semantic memory was significantly more impaired in LOAD than in EOAD patients. The EOAD group was not more affected than the LOAD group in any memory domain. EOAD patients, however, showed significantly poorer performance in other cognitive domains including executive functions and visuoconstructional abilities. A more detailed analysis of the pattern of semantic memory performance among patient groups revealed that the LOAD was more profoundly impaired, in tasks of both spontaneous recall and semantic recognition. Voxel-Based Morphometry (VBM) analyses showed that impaired semantic performance in patients was associated with reduced gray matter volume in the anterior temporal lobe region, while PET-FDG analyses revealed that poorer semantic performance was associated with greater hypometabolism in the left temporoparietal region, both areas reflecting key regions of the semantic network. Results of this study indicate that EOAD and LOAD patients present with distinct patterns of memory impairment, and that a genuine semantic impairment may represent one of the clinical hallmarks of LOAD.

BC Law Magazine Spring/Summer 2004

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BC Law Magazine Spring/Summer 2007

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BC Law Magazine Spring/Summer 2009

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