Analysis of large-scale digital optical neural networks by Feynman diagrams

A new method to study large scale neural networks is presented in this paper. The basis is the use of Feynman- like diagrams. These diagrams allow the analysis of collective and cooperative phenomena with a similar methodology to the employed in the Many Body Problem. The proposed method is applied to a very simple structure composed by an string of neurons with interaction among them. It is shown that a new behavior appears at the end of the row. This behavior is different to the initial dynamics of a single cell. When a feedback is present, as in the case of the hippocampus, this situation becomes more complex with a whole set of new frequencies, different from the proper frequencies of the individual neurons. Application to an optical neural network is reported.

MIA - a free and open source software for gray scale medical image analysis

Background Gray scale images make the bulk of data in bio-medical image analysis, and hence, the main focus of many image processing tasks lies in the processing of these monochrome images. With ever improving acquisition devices, spatial and temporal image resolution increases, and data sets become very large. Various image processing frameworks exists that make the development of new algorithms easy by using high level programming languages or visual programming. These frameworks are also accessable to researchers that have no background or little in software development because they take care of otherwise complex tasks. Specifically, the management of working memory is taken care of automatically, usually at the price of requiring more it. As a result, processing large data sets with these tools becomes increasingly difficult on work station class computers. One alternative to using these high level processing tools is the development of new algorithms in a languages like C++, that gives the developer full control over how memory is handled, but the resulting workflow for the prototyping of new algorithms is rather time intensive, and also not appropriate for a researcher with little or no knowledge in software development. Another alternative is in using command line tools that run image processing tasks, use the hard disk to store intermediate results, and provide automation by using shell scripts. Although not as convenient as, e.g. visual programming, this approach is still accessable to researchers without a background in computer science. However, only few tools exist that provide this kind of processing interface, they are usually quite task specific, and don’t provide an clear approach when one wants to shape a new command line tool from a prototype shell script. Results The proposed framework, MIA, provides a combination of command line tools, plug-ins, and libraries that make it possible to run image processing tasks interactively in a command shell and to prototype by using the according shell scripting language. Since the hard disk becomes the temporal storage memory management is usually a non-issue in the prototyping phase. By using string-based descriptions for filters, optimizers, and the likes, the transition from shell scripts to full fledged programs implemented in C++ is also made easy. In addition, its design based on atomic plug-ins and single tasks command line tools makes it easy to extend MIA, usually without the requirement to touch or recompile existing code. Conclusion In this article, we describe the general design of MIA, a general purpouse framework for gray scale image processing. We demonstrated the applicability of the software with example applications from three different research scenarios, namely motion compensation in myocardial perfusion imaging, the processing of high resolution image data that arises in virtual anthropology, and retrospective analysis of treatment outcome in orthognathic surgery. With MIA prototyping algorithms by using shell scripts that combine small, single-task command line tools is a viable alternative to the use of high level languages, an approach that is especially useful when large data sets need to be processed.

Robust control of underactuated wheeled mobile manipulators using GPI disturbance observers

This article describes the design of a linear observer–linear controller-based robust output feedback scheme for output reference trajectory tracking tasks in the case of nonlinear, multivariable, nonholonomic underactuated mobile manipulators. The proposed linear feedback scheme is based on the use of a classical linear feedback controller and suitably extended, high-gain, linear Generalized Proportional Integral (GPI) observers, thus aiding the linear feedback controllers to provide an accurate simultaneous estimation of each flat output associated phase variables and of the exogenous and perturbation inputs. This information is used in the proposed feedback controller in (a) approximate, yet close, cancelations, as lumped unstructured time-varying terms, of the influence of the highly coupled nonlinearities, and (b) the devising of proper linear output feedback control laws based on the approximate estimates of the string of phase variables associated with the flat outputs simultaneously provided by the disturbance observers. Simulations reveal the effectiveness of the proposed approach.

Effect of magnetic field on current colection on bare tether in LEO

An eiectrodynamic Tether is a long thin conductive string deployed from a spacecraft. A part of the ED tether near one end, which is rendered positive by the Electromotive force (EMF)along the tether, collects electrons from the ambient plasma. In the frame of reference moving with theter, ions flow toward the tether, get deflected near the tether by its high positive potential and create a wake. Due to the asymmetry of plasma distribution and the weak but significant Geomagnetic field, the conventional probe theory becomes almost inapplicable. Computational work for the prediction of current collection is thus necessiated.. In this paper, we analyze effects of magnetic field on velocity distribution funtion at a point that is far from the tether, and discuss a new way to treat electrons at computational boundary. Three cases with different magnetic field are simulated and compiled so as to provide a part of the pre-flight prediction of the space experiment by NASA ProSEDS, which is planned September 2002.

Simulación numérica computacional de fenómenos dinámicos

En este proyecto se trata la simulación numérica de un fenómeno dinámico, basado en el comportamiento de una onda transmitida a lo largo de una cuerda elástica de un instrumento musical, cuyos extremos se encuentran anclados. El fenómeno físico, se desarrolla utilizando una ecuación en derivadas parciales hiperbólicas con variables espacial y temporal, acompañada por unas condiciones de contorno tipo Dirichlet en los extremos y por más condiciones iniciales que dan comienzo al proceso. Posteriormente se han generado algoritmos para el método numérico empleado (Diferencias finitas centrales y progresivas) y la programación del problema aproximado con su consistencia, estabilidad y convergencia, obteniéndose unos resultados acordes con la solución analítica del problema matemático. La programación y salida de resultados se ha realizado con Visual Studio 8.0. y la programación de objetos con Visual Basic .Net In this project the topic is the numerical simulation of a dynamic phenomenon, based on the behavior of a transmitted wave along an elastic string of a musical instrument, whose ends are anchored. The physical phenomenon is developed using a hyperbolic partial differential equation with spatial and temporal variables, accompanied by a Dirichlet boundary conditions at the ends and more initial conditions that start the process. Subsequently generated algorithms for the numerical method used (central and forward finite differences) and the programming of the approximate problem with consistency, stability and convergence, yielding results in line with the analytical solution of the mathematical problem. Programming and output results has been made with Visual Studio 8.0. and object programming with Visual Basic. Net

Paso superior en la conexión Martutene-Hospitales con la A-8

El paso superior sobre la GI-40, incluido en la conexión entre Martutene-Hospitales y la A-8, se resuelve, debido a la imposibilidad de disponer pilas intermedias, mediante un vano único de 37,6 m, minimizando, a su vez, la afección al tráfico durante la construcción. La estructura metálica principal sustenta un tablero inferior mixto encofrado con chapa grecada, satisfaciendo los requerimientos de gálibo de la vía inferior y mejorando la seguridad durante la construcción. El esquema estructural, a medio camino entre un arco ?bow-string? y una viga Vierendeel de canto variable, permite alcanzar una disposición robusta, de formas limpias y de alta permeabilidad visual, que, junto con el acabado ofrecido por los estribos de suelo reforzado, configuran un marco estético de calidad que resulta compatible con una alta optimización económica y funcional de la estructura.

Deux sonates et La Coquette pour forte piano [Música notada] : oeuvre VI

Encuadernado con: A favourite concerto for the piano-forte or harpsichord with accompaniments for two violins and a violoncello ; Trois trios pour le clavecin ou piano-forte avec violon [et] violoncelle : oeuvre 41. Liv. I y Liv. II ; Haydn's celebrated overture composed for & performed at Mr. Salomon's concert Hanover-Square : adapted for the piano-forte, with an accompaniment for a violin & violoncello ad libitum. N. 2 y N. 3 ; [Sonatas] ; Sonata for the pianoforte or harpsichord : op. 66

A favourite concerto for the piano-forte or harpsichord with accompaniments for two violins and a violoncello [Música notada]

Hay un ejemplar encuadernado con: Deux sonates et La Coquette pour forte piano (XVIII/2815)

Haydn's celebrated overture composed for & performed at Mr. Salomon's concert Hanover-Square : adapted for the piano-forte, with an accompaniment for a violin & violoncello ad libitum. N. 2, Sinfonia II [Música notada]

Hay un ejemplar encuadernado con: Deux sonates et La Coquette pour forte piano (XVIII/2815). Firma autógrafa de J.C. Salomon en la port.

Haydn's celebrated overture composed for & performed at Mr. Salomon's concert Hanover-Square : adapted for the piano-forte, with an accompaniment for a violin & violoncello ad libitum. N. 3, Sinfonia III [Música notada]

Hay un ejemplar encuadernado con: Deux sonates et La Coquette pour forte piano (XVIII/2815). Firma autógrafa de J.C. Salomon en la port.

Dust effects on PV array performance: in-field observations with non-uniform patterns

This paper presents the impact of non-homogeneous deposits of dust on the performance of a PV array. The observations have been made in a 2-MW PV park in the southeast region of Spain. The results are that inhomogeneous dust leads to more significant consequences than the mere short-circuit current reduction resulting from transmittance losses. In particular, when the affected PV modules are part of a string together with other cleaned (or less dusty) ones, operation voltage losses arise. These voltage losses can be several times larger than the short-circuit ones, leading to power losses that can be much larger than what measurements suggest when the PV modules are considered separately. Significant hot-spot phenomena can also arise leading to cells exhibiting temperature differences of more than 20 degrees and thus representing a threat to the PV modules' lifetime.

Toward a consolidation of the CPV-specific-test procedures for inverters

The inverter in a photovoltaic system assures two essential functions. The first is to track the maximum power point of the system IV curve throughout variable environmental conditions. The second is to convert DC power delivered by the PV panels into AC power. Nowadays, in order to qualify inverters, manufacturers and certifying organisms use mainly European and/or CEC efficiency standards. The question arises if these are still representative of CPV system behaviour. We propose to use a set of CPV – specific weighted average and a representative dynamic response to have a better determination of the static and dynamic MPPT efficiencies. Four string-sized commercial inverters used in real CPV plants have been tested.

Polycaps: Reversibly formed polymeric capsules

Described are assemblies consisting of polymeric capsules, “polycaps,” formed from two calix[4]arene tetraureas covalently connected at their lower rims. In these structures self-assembly leads to reversibly formed capsule sites along a chain, reminiscent of beads on a string. Their dynamic behavior is characterized by 1H NMR spectroscopy through encapsulation of guest species, reversible polymerization, and the formation of sharply defined hybrid capsules.

A Polymer Model for the Structural Organization of Chromatin Loops and Minibands in Interphase Chromosomes

A quantitative model of interphase chromosome higher-order structure is presented based on the isochore model of the genome and results obtained in the field of copolymer research. G1 chromosomes are approximated in the model as multiblock copolymers of the 30-nm chromatin fiber, which alternately contain two types of 0.5- to 1-Mbp blocks (R and G minibands) differing in GC content and DNA-bound proteins. A G1 chromosome forms a single-chain string of loop clusters (micelles), with each loop ∼1–2 Mbp in size. The number of ∼20 loops per micelle was estimated from the dependence of geometrical versus genomic distances between two points on a G1 chromosome. The greater degree of chromatin extension in R versus G minibands and a difference in the replication time for these minibands (early S phase for R versus late S phase for G) are explained in this model as a result of the location of R minibands at micelle cores and G minibands at loop apices. The estimated number of micelles per nucleus is close to the observed number of replication clusters at the onset of S phase. A relationship between chromosomal and nuclear sizes for several types of higher eukaryotic cells (insects, plants, and mammals) is well described through the micelle structure of interphase chromosomes. For yeast cells, this relationship is described by a linear coil configuration of chromosomes.

GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of Gαi subunits

GAIP (G Alpha Interacting Protein) is a member of the recently described RGS (Regulators of G-protein Signaling) family that was isolated by interaction cloning with the heterotrimeric G-protein Gαi3 and was recently shown to be a GTPase-activating protein (GAP). In AtT-20 cells stably expressing GAIP, we found that GAIP is membrane-anchored and faces the cytoplasm, because it was not released by sodium carbonate treatment but was digested by proteinase K. When Cos cells were transiently transfected with GAIP and metabolically labeled with [35S]methionine, two pools of GAIP—a soluble and a membrane-anchored pool—were found. Since the N terminus of GAIP contains a cysteine string motif and cysteine string proteins are heavily palmitoylated, we investigated the possibility that membrane-anchored GAIP might be palmitoylated. We found that after labeling with [3H]palmitic acid, the membrane-anchored pool but not the soluble pool was palmitoylated. In the yeast two-hybrid system, GAIP was found to interact specifically with members of the Gαi subfamily, Gαi1, Gαi2, Gαi3, Gαz, and Gαo, but not with members of other Gα subfamilies, Gαs, Gαq, and Gα12/13. The C terminus of Gαi3 is important for binding because a 10-aa C-terminal truncation and a point mutant of Gαi3 showed significantly diminished interaction. GAIP interacted preferentially with the activated (GTP) form of Gαi3, which is in keeping with its GAP activity. We conclude that GAIP is a membrane-anchored GAP with a cysteine string motif. This motif, present in cysteine string proteins found on synaptic vesicles, pancreatic zymogen granules, and chromaffin granules, suggests GAIP’s possible involvement in membrane trafficking.