Efficacy of benznidazol treatment for asymptomatic chagasic patients from state of Rio Grande do Sul evaluated during a three years follow-up

The efficacy of benznidazol on the treatment of chagasic patients from the state of Rio Grande do Sul was evaluated during a three-year follow-up. A cohort of 80 asymptomatic chronic chagasic patients or blood bank donors (49 male and 31 female) was studied. Their ages varied from 17-42 years, with a mean and a median of 30 and 35 years, respectively. The 80 patients presented positive serology, hemoculture and polymerase chain reaction (PCR). They were treated with 5 mg/Kg benznidazol twice a day for 60 days. Serological, parasitological and PCR methods were used to evaluate response. Serology was performed using commercial ELISA and indirect immunofluorescence (IFI) tests, parasitemia was monitored by hemoculture in LIT medium and PCR with primers S35/S36 was used to amplify a Trypanosoma cruzi 330 bp kDNA repetitive sequence. PCR positivity of 240 seropositive individuals was compared using DNA preparations from whole blood/guanidine EDTA (GE), buffy-coat/GE and frozen buffy-coat. Fifty non-chagasic individuals were used as negative controls. PCR positivity was 86.7% for the frozen buffy-coat, 71.7% for the GE/buffy-coat and 69.2% for the GE/whole blood. The hemocultures became negative just after treatment and remained negative during the three years of follow-up. In the third year after treatment, 9/80 (11.3%) patients presented negative PCR and, from those, four also presented negative serological tests. Furthermore, a reduction in three serological titers was observed in 27/80 (33.8%) of the patients treated. Taken together, the results show that four of the 80 (5.0%) chronic chagasic patients from the state of Rio Grande do Sul were cured after treatment with benznidazol.

Susceptibility of Triatoma infestans to deltamethrin in Rio Grande do Sul, Brazil

Strategies for controlling Chagas disease are based on spraying infested houses with pyrethroid insecticides. However, the intense use of these insecticides has promoted resistance of Triatoma infestans and, in Argentina, Bolivia and Southern Brazil, low levels of resistance have been reported. Due to the persistence of T. infestans in the state of Rio Grande do Sul (RS), we evaluated the occurrence of deltamethrin resistance in four strains from different municipalities in comparison to two susceptible strains from Brazil and one resistant strain from Bolivia. The results indicated the absence of resistance in T. infestansfrom RS.

Biomphalaria molluscs (Gastropoda: Planorbidae) in Rio Grande do Sul, Brazil

The present study was aimed at characterising Biomphalaria species using both morphological and molecular (PCR-RFLP) approaches. The specimens were collected in 15 localities in 12 municipalities of the southern region of the state of Rio Grande do Sul, Brazil. The following species were found and identified: Biomphalaria tenagophila guaibensis, Biomphalaria oligoza and Biomphalaria peregrina. Specimens of the latter species were experimentally challenged with the LE Schistosoma mansoni strain, which showed to be refractory to infection.

"Notice historique sur la ville et le comté d'Empurias" de Francesc Jaubert de Paçà (Presentació i facsímil de l'edició de 1823)

Article sobre l' erudit rossellonès M. Jaubert de Passà. El seu interès per la història antiga es plasma en la seva obra 'Notice historique sur la ville et le comte d'Empurias', publicada a Mémoires de la Société Royale des Antiquaires de France (París, 1823), llibret de 86 pàgines que pretén ser una història de la ciutat d'Empúries des d'abans de l'arribada dels foceus fins a principis del segle XVI i de la que els autors d'aquest article n'han editat un facsímil

The first report of the main vector of visceral leishmaniasis in America, Lutzomyia longipalpis (Lutz & Neiva) (Diptera: Psychodidae: Phlebotominae), in the state of Rio Grande do Sul, Brazil

Visceral leishmaniasis (VL) is a widespread zoonosis in Brazil and, up to now, there has been no record of the main vector of its agent, Lutzomyia longipalpis, in the Southern Region. Due to the diagnosis of VL in a dog in October 2008 in the city of São Borja, in the southernmost Brazilian state of Rio Grande do Sul, a collection of phlebotomines was undertaken to detect the presence of the vector Lu. longipalpis. The captures were carried out with CDC light traps on three consecutive nights in 2008. A total of 39 specimens of Lu. longipalpis were captured, thereby increasing the knowledge of the geographical distribution of this important vector.

Projecte de dinamització i gestió del centre d’ atenció al visitant dins l’ APA Itacaré-Serra Grande i Península de Maraú

Aquest projecte es centra en el municipi d’ Itacaré (Bahía, Brasil), el qual actualment pateix una creixent demanda de turisme pel seu atractiu natural. Aquest municipi no disposa de cap Pla de Gestió del Turisme. Per aquest motiu i juntament amb l’ ONG del Brasil “Instituto Aliança” s’ ha treballat en un projecte de creació d’ un centre d’ atenció al visitant. Aquest “Centre de atendimento a ou visitante” està encarat bàsicament a informar i sensibilitzar als turistes i als propis natius de la zona, de les característiques ambientals i culturals de la regió, alhora que es potencia un turisme de base comunitària

Pla de gestió Reserva Natural de Fauna Salvatge de l’Illa de Fluvià

El projecte es basa en l’ elaboració del Pla de gestió de la Reserva Natural de Fauna Salvatge de l’ Illa del Fluvià, coneguda també com l’ Illa de Fares o de Besalú, entre les comarques de la Garrotxa i el Pla de l’ Estany. Es donen un seguit de propostes de millores i també propostes que permetin aprofitar el potencia educatiu de la zona

Phaeohyphomycosis: a clinical-epidemiological and diagnostic study of eighteen cases in Rio Grande do Sul, Brazil

The goal of this study was to review 18 cases of phaeohyphomycosis in Rio Grande do Sul. The records of all of the patients with a diagnosis of phaeohyphomycosis between 1995-2010 were reviewed. Twelve of the 18 patients (66.6%) were male. The average age of the patients was 50 years old (range: 16-74 years). Eleven patients (61%) presented with subcutaneous lesions. Seven patients (38.8%) had received a solid organ transplant. In all of the cases, the presence of melanin in the fungal cells was determined by Fontana-Masson staining of tissue sections and documented. Among the 18 patients, a total of 11 different fungal species were isolated. The causative organisms included Exophiala jeanselmei, Alternaria, Curvularia, Cladophialophora and Colletotrichum gloeosporioides. To our knowledge, this review reports the first case of subcutaneous phaeohyphomycosis caused by C. gloeosporioides in a lung transplant patient. The number of reported cases of phaeohyphomycosis has increased in the last decade. In a number of cases, this increased incidence may be primarily attributed to iatrogenic immunodeficiency.

[Cénotaphe, monument élevé à la mémoire des morts de la grande guerre près de l'Arc de Triomphe] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55020

[Cénotaphe, monument élevé à la mémoire des morts de la grande guerre près de l'Arc de Triomphe] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55019

Cambrai, l'hôtel de ville et Grande place [dégâts dus à la guerre] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55493

Cambrai, Grande place [dégâts dus à la guerre] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55505