991 resultados para Ocular interaction


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... Fluid-Structure Interaction Simulation of Viscoplastic and Fracturing Thin- Shells Subjected to Underwater Shock Loading Ralf Deiterding, Fehmi Cirak, ...

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It is known theoretically [1-3] that infinitely long fluid loaded plates in mean flow exhibit a range of unusual phenomena in the 'long time' limit. These include convective instability, absolute instability and negative energy waves which are destabilized by dissipation. However, structures are necessarily of finite length and may have discontinuities. Moreover, linear instability waves can only grow over a limited number of cycles before non-linear effects become dominant. We have undertaken an analytical and computational study to investigate the response of finite, discontinuous plates to ascertain if these unusual effects might be realized in practice. Analytically, we take a "wave scattering" [2,4] - as opposed to a "modal superposition" [5] - view of the fluttering plate problem. First, we solve for the scattering coefficients of localized plate discontinuities and identify a range of parameter space, well outside the convective instability regime, where over-scattering or amplified reflection/transmission occurs. These are scattering processes that draw energy from the mean flow into the plate. Next, we use the Wiener-Hopf technique to solve for the scattering coefficients from the leading and trailing edges of a baffled plate. Finally, we construct the response of a finite, baffled plate by a superposition of infinite plate propagating waves continuously scattering off the plate ends and solve for the unstable resonance frequencies and temporal growth rates for long plates. We present a comparison between our computational results and the infinite plate theory. In particular, the resonance response of a moderately sized plate is shown to be in excellent agreement with our long plate analytical predictions. Copyright © 2010 by ASME.

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This paper describes large-scale simulations of compressible flows over a supersonic disk-gap-band parachute system. An adaptive mesh refinement method is used to resolve the coupled fluid-structure model. The fluid model employs large-eddy simulation to describe the turbulent wakes appearing upstream and downstream of the parachute canopy and the structural model employed a thin-shell finite element solver that allows large canopy deformations by using subdivision finite elements. The fluid-structure interaction is described by a variant of the Ghost-Fluid method. The simulation was carried out at Mach number 1.96 where strong nonlinear coupling between the system of bow shocks, turbulent wake and canopy is observed. It was found that the canopy oscillations were characterized by a breathing type motion due to the strong interaction of the turbulent wake and bow shock upstream of the flexible canopy. Copyright © 2010 by ASME.

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Sir John Egan’s 1998 report on the construction industry (Construction Task Force 1998) noted its confrontational and adversarial nature. Both the original report and its subsequent endorsement in Accelerating Change (Strategic Forum 2002) called for improved working relationships—so-called ‘integration’—within and between both design and construction aspects. In this paper, we report on our observations of on-site team meetings for a major UK project during its construction phase. We attended a series of team meetings and recorded the patterns of verbal interaction that took place within them. In reporting our findings, we have deliberately used a graphical method for presenting the results, in the expectation that this will make them more readily accessible to designers. Our diagrams of these interaction patterns have already proved to be intuitively and quickly understood, and have generated interest and discussion among both those we observed and others who have seen them. We noted that different patterns of communication occurred in different types of meetings. Specifically, in the problem-solving meeting, there was a richness of interaction that was largely missing from progress meetings and technical meetings. Team members expressed greater satisfaction with this problem-solving meeting where these enriched exchanges took place. By making comparisons between the different patterns, we are also able to explore functional roles and their interactions. From this and other published evidence, we conclude that good teamworking practices depend on a complex interplay of relations and dependencies embedded within the team.

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Turbulent combustion of stoichiometric hydrogen-air mixture is simulated using direct numerical simulation methodology, employing complex chemical kinetics. Two flame configurations, freely propagating and V-flames stabilized behind a hot rod, are simulated. The results are analyzed to study the influence of flame configuration on the turbulence-scalar interaction, which is critical for the scalar gradient generation processes. The result suggests that this interaction process is not influenced by the flame configuration and the flame normal is found to align with the most extensive strain in the region of intense heat release. The combustion in the rod stabilized flame is found to be flamelet like in an average sense and the growth of flame-brush thickness with the downstream distance is represented well by Taylor theory of turbulent diffusion, when the flame-brushes are non-interacting. The thickness is observed to saturate when the flame-brushes interact, which is found to occur in the simulated rod stabilized flame with Taylor micro-scale Reynolds number of 97. © 2011 American Institute of Physics.

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AIM: To study the interaction between human interleukin-16 (IL-16) and the receptor CD4 (T-lymphocyte differentiation antigen) of human immunodeficiency virus type 1 (HIV-1). METHODS: Two structurally con served regions (SCRs) of human IL-16 were built by the SYBYL/Biopolymer module using the corresponding transmembrane (TM) domain of human interleukin-1 (HIL-4) and HIL-2 as the templates. The coordinates for amino-terminal residue sequence, carboxyl-terminal residue sequences, and cytoplasm loops were generated using Biopolymer's LOOP SEARCH algorithm. RESULTS: HIL-16 first formed a homodimer, then contacted with CD4 dimer further forming a dimeric complex. Subsequently, the dimeric complex constructed the tetrameric complex by two disulfide bridges between the cysteines of HIL-16 (Cys31-Cys31). CONCLUSION: The interaction model is useful to propose the action mechanism of HIL-16 and is beneficial for rational designing of novel anti-HIV drugs.

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Statistical dialogue models have required a large number of dialogues to optimise the dialogue policy, relying on the use of a simulated user. This results in a mismatch between training and live conditions, and significant development costs for the simulator thereby mitigating many of the claimed benefits of such models. Recent work on Gaussian process reinforcement learning, has shown that learning can be substantially accelerated. This paper reports on an experiment to learn a policy for a real-world task directly from human interaction using rewards provided by users. It shows that a usable policy can be learnt in just a few hundred dialogues without needing a user simulator and, using a learning strategy that reduces the risk of taking bad actions. The paper also investigates adaptation behaviour when the system continues learning for several thousand dialogues and highlights the need for robustness to noisy rewards. © 2011 IEEE.

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The performance of a transonic fan operating within nonuniform inlet flow remains a key concern for the design and operability of a turbofan engine. This paper applies computational methods to improve the understanding of the interaction between a transonic fan and an inlet total pressure distortion. The test case studied is the NASA rotor 67 stage operating with a total pressure distortion covering a 120-deg sector of the inlet flow field. Full-annulus, unsteady, three-dimensional CFD has been used to simulate the test rig installation and the full fan assembly operating with inlet distortion. Novel post-processing methods have been applied to extract the fan performance and features of the interaction between the fan and the nonuniform inflow. The results of the unsteady computations agree well with the measurement data. The local operating condition of the fan at different positions around the annulus has been tracked and analyzed, and this is shown to be highly dependent on the swirl and mass flow redistribution that the rotor induces ahead of it due to the incoming distortion. The upstream flow effects lead to a variation in work input that determines the distortion pattern seen downstream of the fan stage. In addition, the unsteady computations also reveal more complex flow features downstream of the fan stage, which arise due to the three dimensionality of the flow and unsteadiness. © 2012 American Society of Mechanical Engineers.