Colangiohepatite Felina

Cholangiohepatitis is a common hepatic disorder in cats that is second only to hepatic lipidosis in frequency. The cholangitis-cholangiohepatitis complex is known as the diseases that involve the biliar tract inflammation and may extend to the liver. The classification of the cholangiohepatitis is still controversial, in this present study the following classification was used: Acute Cholangiohepatitis, Chronic Cholangiohepatitis, Lymphocitic Cholangitis. The cholangiohepatitis may be associated with pancreatitis and inflammatory bowel disease, this association is known as feline triaditis. The diagnosis is based on the clinical signs, alterations in laboratory exams and ultrasonography alterations, but the definitive diagnosis is only possible through liver biopsy. The treatment for each type of cholangiohepatitis differs, hence the importance of the right diagnosis. This study aimed to do a review over the ethiology, clinical presentation, diagnosis and treatment for this disease

Perfil do estilo de vida e conhecimento dos fatores de risco para doenças e agravos n��o transmiss��veis em praticantes de atividade f��sica em UBS de Rio Claro

Introdu����o: As Doenças Cr��nicas N��o Transmiss��veis (DANTS) s��o um grupo de enfermidades cujo processo de instala����o no organismo geralmente se inicia com altera����es, a preven����o dessas afec����es tem sido um grande desafio para a sa��de p��blica. As principais DANTS s��o: c��ncer, doenças do cora����o (angina e infarto do mioc��rdio), doenças do pulm��o (como enfisema, bronquite e asma), doenças da circula����o como acidente vascular cerebral e hipertens��o arterial, doenças metab��licas como diabetes, hipercolesterolemia, a obesidade, relacionadas com condi����es de vida (como o estresse, depress��o e ansiedade). Existem in��meros Fatores de Risco (FR) relacionados a estes tipos de doenças, cuja remo����o, ou atenua����o, pode contribuir para o decl��nio da mortalidade.Objetivo: Associar comportamentos e conhecimentos de FR para doenças e agravos n��o transmiss��veis de mulheres praticantes de AF atrav��s do projeto Sa��de Ativa Rio Claro, este visa desenvolver e difundir pr��ticas de interven����o cientificamente orientadas que incorporem a AF como parte integrante de um h��bito de vida saud��vel para todas as pessoas. Metodologia: Participaram do estudo 100 mulheres, com idade m��dia de 57,7((�� 13,1), foram aplicados dois question��rios, sendo o primeiro sobre conhecimento de FR para DANTS e o segundo avaliou comportamentos relacionados ao estilo de vida: n��vel de AF, consumo de ��lcool, dieta, taxa de colesterol, n��vel de estresse, tabagismo.Resultados e Discuss��o: N��o houve associa����o entre conhecimento e comportamento, o conhecimento isoladamente n��o foi suficiente para promover modifica����es no comportamento das pessoas. A analise estat��stica utilizada foi o Qui Quadrado (x��) de 1 grau de liberdade e com n��vel de signific��ncia de p= 0,05. Conclus��o: Um grupo de pessoas pode conhecer os benef��cios de um comportamento e n��o ter tempo ou recursos suficientes...(Resumo completo, clicar acesso eletr��nico abaixo)

Avalia����o da atividade antibacteriana de esp��cies vegetais utilizadas em doenças do trato digest��rio: Baccharis trimera (LESS.) DC. E Casearia sylvestris Swartz

Baccharis trimera (Less.) DC. Asteraceae e Casearia sylvestris Swartz Salicaceae s��o plantas nativas do Brasil e de uso tradicional em doenças do trato digest��rio. Seus extratos e subst��ncias purificadas apresentaram diversas atividades farmacol��gicas (ex.antiulcerog��nica, antimicrobiana) e baixa toxicidade. O Helicobacter pylori (bacilo gram-negativo) coloniza o est��mago humano, associada ao maior risco de incid��ncia de v��rias doenças (��lceras p��pticas, linfomas e adenocarcinomas g��stricos). Com o objetivo de avaliar a atividade antibacteriana de diferentes extratos, fra����es e subst��ncias de ambas as plantas medicinais, extratos de partes a��reas de B. trimera e de folhas de C. sylvestris foram preparados utilizando-se t��cnicas de macera����o, obtendo-se o extrato acetato de etila e etan��lico de C. sylvestris e acetato de etila, etan��lico, etanol 70% e hex��nico de B. trimera. Estes foram fracionados e analisados por t��cnicas cromatogr��ficas. Os extratos e suas fra����es e subst��ncias foram submetidos a ensaios para avalia����o da atividade antibacteriana para a determina����o da concentra����o inibit��ria m��nima (CIM). O m��todo utilizado para os ensaios foi a dilui����o em microplacas usando as bact��rias Helicobacter pylori ATCC 43504, Staphylococcus aureus ATCC 25923 e Escherichia coli ATCC 25922. A partir do fracionamento do extrato acetato de etila de B. trimera e do extrato etan��lico de C. sylvestris foram obtidas oito fra����es distintas do EAcBt e a fra����o de diterpenos do EEtCs. A an��lise em CCD demonstrou a presen��a de casearina X, B e caseargrewiina F na fra����o de diterpenos (EFSCs2). Os extratos da B. trimera EAcBt, EEtBt e EEt70Bt e da C. sylvestris EAcCs e EEtCs apresentaram atividade anti-H. pylori, com valores de CIM de 250, 500, 500, 125 e 750 ���g/mL, respectivamente... (Resumo completo, clicar acesso eletr��nico abaixo)

Miostatina e redu����o da massa muscular em doenças cr��nicas

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Exames laboratoriais importantes no diagn��stico da Piometra canina

Canine Pyometra is a uterine disease that occurs in sexually mature bitches, with higher incidence in nulliparous and animals over 4 years and is characterized by presenting an accumulation of pus in the uterine lumen, usually occurring in diestrus. Laboratory tests are important tools for the detection of metabolic abnormalities associated with sepsis and renal function, which are serious consequences of pyometra. In blood the main findings are normochromic non-regenerative anemia, presence of dehydration, and sometimes thrombocytopenia. The WBC count may be normal but most often occurs a neutrophilic leukocytosis with a left shift, monocytosis and the presence of toxic neutrophils. In less than 1 / 3 of the animals the presence of azotemia is present and a density lower than 1035 is detected in the urine of almost 90% of bitches which may be in normal range at the onset of the desease. Urinary protein loss is rare but the protein may be elevated in the reagent strip due to urinary contamination by uterine secretion. The increase of gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), aspartate aminotransferase (AST) and creatine kinase (CK) may be present, indicating disorders in the liver. Currently, additional laboratory tests are being studied for the diagnosis of pyometra and its prognosis, such as the measurement of C-reactive protein and fibrinogen for monitoring the recovery of the inflammatory process and the urine electrophoresis to characterize the origin of proteinuria in these animals . The aim of this work is to review the literature on the main laboratory tests that aid the diagnosis of Pyometra

Doenças relacionadas ao trabalho e sua rela����o com diferentes tipos de personalidade

Com a revolu����o industrial e tecnol��gica, o trabalho bra��al foi e vem sendo substitu��do por m��quinas e equipamentos eletr��nicos, na inten����o de poupar o ser humano e diminuir gastos e despesas com sal��rios e aumento da produtividade. Devido a esses fatores, o trabalho tornou-se repetitivo, o que possibilitou o aparecimento de doenças como a L.E.R./D.O.R.T.. Esse contexto despertou o interesse na realiza����o desta pesquisa, cujo objetivo �� relacionar essas patologias e suas incid��ncias �� personalidade das pessoas atrav��s de um sistema denominado Eneagrama. Por meio de uma revis��o de literatura nas ��reas de Gin��stica Laboral, L.E.R./D.O.R.T. e Eneagrama, foi poss��vel obter informa����es que levou �� analisar que os Tipos do Eneagrama 1 (Perfeccionista), 3 (Bem Sucedido), 8(Confrontador) e 9 (Preservacionista), apresentam alta probabilidade de incid��ncia de L.E.R./D.O.R.T.. Os Tipos 4 (Rom��ntico), 5 (Observador), 6 (Questionador) e 7 (Sonhador), apresentam baixa probabilidade de incid��ncia. Enquanto que o Tipo 2 (Prestativo) �� neutro quanto ao resultado. Concluindo assim, que o aparecimento dessas doenças pode estar relacionado a um ou mais tipos espec��ficos de personalidade, e que aplicando esse sistema nas empresas, acompanhado da realiza����o da Gin��stica Laboral, podemos contribuir na diminui����o de casos como esses.

Platinosom��ase em felinos dom��sticos: um diferencial para obstru����o biliar

The platinosomiase is a disease the hepatobiliary system of domestic felines being caused by trematode Platynosomum fastosum. The life cycle of the parasite includes the presence of three intermediate hosts (snails, terrestrial isopodes, lizards or frogs). The cat is considered definitive host of the parasite and acquires the infection eating a vertebrate intermediate host containing metacercariae. The adult parasites generally inhabit the liver, gallbladder and bile ducts of cats. The severity of clinical manifestations depends mainly on the number of flukes in the biliary tract. Many animals are asymptomatic or exhibit nonspecific clinical manifestations such as anorexia, lethargy, weight loss, vomiting and diarrhea. In large infestations can occur biliary obstruction resulting in jaundice, cirrhosis, hepatitis cholangiohepatitis and even death. The definitive diagnosis is accomplished through by the detection of fluke eggs in feces or through laparotomy and liver biopsy. Treatment should be based on the use of anthelmintic for the elimination of the parasite and supportive therapy for the animal. Prevention is difficult due to predatory nature of the cat. The control can be accomplished through periodic fecal examinations

Histologia comparada de br��nquias, fígado e sangue em peixes da esp��cie Prochilodus lineatus, expostos a ��guas contaminadas

Os estudos hematol��gicos das diferentes esp��cies de peixes s��o de interesse ecol��gico e fisiol��gico, auxiliando na compreens��o da rela����o entre as caracter��sticas sangu��neas, a filogenia, a atividade f��sica, o h��bitat e a adaptabilidade dos peixes ao ambiente. No experimento realizado foram testados os efeitos de ��guas contaminadas em par��metros hematol��gicos de peixes da esp��cie Prochilodus lineatus, em per��odos de coleta de 7 e 20 dias, nos quais o sangue foi coletado com seringas heparinizadas, foram montadas l��minas de esfrega��o , as quais foram coradas pelo corante de Leishman. Estas l��minas foram analisadas e fotografadas com o aux��lio de um microsc��pio ��ptico Leica, no qual foram feitas contagens totais de c��lulas brancas e contagens diferenciais de tromb��citos e leuc��citos, para a an��lise estat��stica. O grupo exposto ao Lago Azul apresentou uma eleva����o no n��mero de leuc��citos e no total de c��lulas brancas, evidenciando que os contaminantes qu��micos do ambiente estavam atuando de forma semelhante a um ant��geno no corpo do animal fazendo com que suas c��lulas de defesa se proliferassem. Quanto ao grupo exposto ao detergente, observou-se que ap��s os vinte dias de experimento ocorreu uma diminui����o no n��mero de tromb��citos. Tais resultados evidenciam que a varia����o no n��mero de leuc��citos apresentou-se como um indicador de polui����o ambiental e que os detergentes biodegrad��veis podem em certo tempo de exposi����o ocasionar um d��ficit em fun����es vitais de peixes como �� coagula����o e a preven����o contra infec����es, eventos ligados diretamente com os tromb��citos. A maioria dos vertebrados aqu��ticos possui br��nquias, estruturas especializadas nas trocas gasosas e respons��veis por grande parte das trocas i��nicas. Este ��rg��o acaba por absorver grande parte das subst��ncias presentes na ��gua, que ao ca��rem na...(Resumo completo, clicar acesso eletr��nico abaixo)

Brucelose e tuberculose como doenças ocupacionais em matadouros-frigor��ficos de bovinos no Brasil

Tuberculosis and brucellosis are important diseases in national scenario, as they affect national cattle and can be transmitted to human, as they are zoonosis. The transmission risk increases mostly for those who have strict contact with animals, as is this case of slaughterhouse workers. This paper presents a bibliographic review of data referent to both diseases occurring in bovine slaughterhouse workers in Brazil, characterizing as occupational zoonosis diseases. We still have few data available of this subject, what raise difficulties to know the real incidence of both diseases in national cattle and in people who work in contact with animals, and most of the time are not instructed to the risk that they are exposed and how to prevent it. It���s important to know which is the situation of both diseases so that prevention and even eradication measures can be taken, as we know the Veterinary has an essential function in this matter, protecting animal health as much as protecting national public health

Prolifera����o e Morte Celular (Apoptose) avaliadas em ratos Lewis ap��s tratamento com mistura de praguicidas em baixas doses

The use of pesticides in Brazil has intensified over the years. And since 2009 it was ranked as the largest market for pesticides worldwide. The consequential diffuse contamination of the environment is therefore due to the increasing number of chemicals of different classes, origins and modes of action. Little is known about the action of pesticides on human health in situations of co-exposure. Possible toxic effects are not restricted to agricultural and industrial workers, but also the general population that may be exposed continuously to its residues in food and water. Although these pesticides are mostly present in the environment at low doses, it must be considered that possible cumulative or synergistic effects may occur when there are concurrent or sustained exposure for two or more of these agents, which can lead to late manifestation of subclinical damages, sometimes irreversible. Thus, the specific objective of this study was to assess the effect of carcinogenesis promotion of a mixture of pesticides at low doses and analyze the phenomena of cell proliferation and apoptosis in rat liver. A total of 50 male Lewis rats was separated into 5 groups for 8 weeks in a medium term hepatocarcinogenesis model. The three different classes of pesticides (dieldrin, dicofol, endosulfan, dichlorvos and permethrin), whose residues were detected by ANVISA during the period from 2001 to 2005 in tomatoes cultures, were added to the feed of rats initiated to hepatocarcinogenesis with diethylnitrosamine (DEN- 200mg/kg ip). We used two different mixtures, one with no toxic effects at doses (MEX1) referring to the NOEL (no-observed-effect level) and another at doses LOEL / LEL / LOAEL (Lowest-observed-effect level / Lowest-effect level / Lowest -observed-adverse-effect level), to the installation of adverse effects (MEX2), derived from chronic studies. All animals ...(Complete abstract click electronic access below)

Doenças osteoarticulares em pequenos animais

Osteoarticular diseases are very frequent in small animals, especially dogs. Osteoarthritis is the most common degenerative arthropathy in cats and dogs. It is one of the most important skeletal disease in small animals and it is divided into two broad classes: secondary and genetics. The secondary is originated from situations that can cause joint instability like as trauma, ligament problems and obesity among others. The gene for osteoarthritis comes from hereditary problems such as hip dysplasia, elbow dysplasia and other diseases that can cause articular instability. The hereditary osteoarticular diseases are important only because they can result in the osteoarthritis. It is important to prevent the joint instability and consequently the clinical signs that affect the quality of life of the animals. The most common clinical signs are intermittent claudication, a decrease in performance, reluctance to jump and climb ladders among others. To prevent the clinical signs or mitigate them, the treatments need to be focused on pain control and especially restoration of the affected joint. The treatments most used are the medical and surgery. Anti-inflammatory and analgesics are used in large scale for pain control and to inhibit inflammatory mediators. Furthermore, medical treatment includes weight reduction, physiotherapy and proper nutrition along with anti-inflammatory and analgesics. Surgical treatments are indicated if there is an inadequate response to medical treatment. Physiotherapy is often used in conjunction with other treatments. Besides the reduction of weight is essential and obesity is unacceptable. Cats also suffer from osteoarthritis, but the diagnosis is rarer than in dogs. Usually the cat���s owners relate the reluctance to jump and drop in performance with senility, and when the disease is diagnosed is already in... (Complete abstract click electronic access below)

Educa����o ambiental e pr��ticas pedag��gicas em escolas do ensino b��sico: o que dizem as teses e disserta����es produzidas no estado de S��o Paulo?

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Exposi����o perinatal ao chumbo e desnutri����o intra-uterina, isoladamente ou em associa����o: efeitos cardiovasculares em ratos rec��m-desmamados

Plumbism is considered the oldest occupational disease. Among the pathophysiological effects associated with lead (Pb) are cardiovascular disorders. Many diseases that develop later in life are determined during the early stages of life, under the influence of exposure and preferred diet of the mother. Still, one should consider that many environmental contaminants at levels not harmful can determine pathophysiological processes if physical or chemical stressors and/or pathological conditions are present. In this context, the intrauterine malnutrition may represent an additional risk factor in exposure to Pb during pregnancy and lactation. For these reasons, the objective of this study was to evaluate the cardiovascular risk of weaned rats that have suffered perinatal exposure to Pb and intrauterine malnutrition, alone or in combination. After mating, female rats were divided into control (ctrl, ad libitum), food restriction (RA, the same diet 50% of consumption in the control group during pregnancy), exposed to Pb (500 ppm Pb in drinking water during pregnancy and lactation) and association (As, received the last two procedures in combination). Cumulative concentration-effect curves (CECs) to CaCl2 and noradrenaline (NA) were obtained in rings with and without endothelium of the same thoracic aorta from male weaned rats (23-25 days old). Maternal weight, litter weight, weight and number of pups at birth, anogenital distance, arterial blood pressure (ABP) and weight of tissues (kidney, liver, aorta, left ventricle) were evaluated. Changes in vascular reactivity were assessed by the maximum response (MR) and 50% effective concentration (EC50). Data were presented as mean �� SEM. Statistical analysis was performed by multifactorial analysis of variance and Tukey's post test. Body weight of dams did not differ between the experimental groups, except on the...(Complete abstract click electronic access below)

Influ��ncia do Programa Sa��de Ativa Rio Claro nas vari��veis bioqu��micas relacionadas a doenças cardiovasculares de seus praticantes

A inatividade f��sica �� uma das principais causas de morte no mundo, e um dos principais fatores de risco para doenças n��o transmiss��veis. Os fatores de risco destas doenças podem ser prevenidos com modifica����es no estilo de vida, que reduz eventos cardiovasculares e aumenta a sobrevida de pacientes portadores ou em risco de coronariopatias. Entendendo de como estes agentes casuais se predisp��em ao surgimento de cardiopatias, o acompanhamento de fatores de risco ajudam na identifica����o de sinais antecessores �� doen��a, que podem ser modificados, atenuados e at�� mesmo revertidos. O objetivo do presente estudo foi de verificar a influ��ncia de um ano de pr��tica regular de Atividade F��sica nas vari��veis bioqu��micas (bioqu��micas (glicose, triglic��rides, HDL, LDL, e colesterol total), circunfer��ncia de quadril e abdominal e Indice de Massa Corporal (IMC) de seus praticantes. Participaram do presente estudo 25 mulheres com idade superior a 40 anos participantes iniciantes do Programa de Exerc��cio F��sico na Aten����o B��sica da cidade de Rio Claro-SP. As atividades foram realizadas com frequ��ncia de tr��s vezes por semana, em sess��es de 60 minutos. Foram realizadas tr��s an��lises laboratoriais (in��cio, ap��s 4 meses e um ano de interven����o) das vari��veis bioqu��micas (glicose, triglic��rides, HDL, LDL, e colesterol total). Os principais resultados do presente estudo demonstraram que ap��s quatros meses de interven����o a circunfer��ncia abdominal e o LDL apresentaram menores valores do que no in��cio do programa. Entretanto, ap��s um ano de interven����o a circunfer��ncia do quadril, abdominal, LDL, glicose e colesterol total apresentaram maiores valores do que quando comparado com os valores ap��s os 4 meses. Com base nos resultados antropom��tricos percebe-se que houve melhores resultados aos quatro meses de interven����o do que com um ano de interven����o. Provavelmente o que ocorreu no caso do presente estudo se deve pela...

Altera����es hep��ticas em c��es intoxicados experimentalmente por sementes de Crotalaria spectabilis

P��s-gradua����o em Medicina Veterin��ria - FCAV