Antecedents, psychiatric characteristics and follow-up of adolescents hospitalized for suicide attempt of overwhelming suicidal ideation.

To evaluate the socio-demographic as well as the health and psychiatric profiles of adolescents hospitalised for suicide attempt or overwhelming suicide ideation and to assess repetition of suicide attempt over a period of 18 months. Between April 2000 and September 2001, all patients aged 16 to 21 years admitted to the University Hospitals of Geneva and Lausanne for suicide attempt or ideation were included in the study. At this time (T0) semi-structured face to face interviews were conducted to identify socio-demographic data, mental health and antecedents regarding suicidal conducts. Current psychiatric status was assessed with the MINI (Mini International Neuropsychiatric Instrument). At T1 and T2, reassessments included psychiatric status (MINI) as well as lifestyles, socio-professional situation and suicidal behaviours. At T0, 269 subjects met the study criteria, among whom 83 subjects (56 girls and 27 boys) left the hospital too quickly to be involved or refused to participate in the study (final sample at T0: 149 girls; 37 boys). The participation rate at T1 and T2 was respectively 66% and 62% of the original sample. The percentage of adolescents meeting the criteria for psychiatric diagnoses (91%) was high: affective disorder (78%); anxiety disorder (64%); substance use disorder (39%); eating disorder (9%); psychotic disorder (11%); antisocial personality (7%) with most subjects (85%) having more than one disorder. Around 90% of the subjects interviewed at T1, and/or T2, had received follow-up care after their hospitalisation, either by a primary care physician or a psychotherapist or both. Two subjects died of violent death and 18% made a further suicide attempt. Most adolescents hospitalised for suicidal episodes suffer from psychiatric problems which should be addressed by a careful psychiatric assessment, followed up if needed by a structured after care plan.

Could concomitant radio-chemotherapy improve the outcomes of early-stage node negative anal canal cancer patients? A retrospective analysis of 122 patients.

One hundred twenty-two early-stage anal canal cancer patients (median age: 69 years) were treated with curative radiotherapy with (70 patients) or without (52 patients) concomitant chemotherapy. Median follow-up was 65 months (range: 4-238). At multivariate analysis, concomitant chemotherapy significantly improved local control (p = .007). Local control significantly influenced all considered endpoints, except the metastases free survival. The global rates of G3-G4 acute and late toxicity were 13.1% and 8.2%, respectively, and they were not increased by concomitant chemotherapy. Finally, concomitant chemotherapy is efficacious and safe in the treatment of T1-2N0 anal canal cancer patients and should be prospectively studied.

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing-remitting multiple sclerosis.

BACKGROUND: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast "connectometry" approach to assess the structural and functional integrity of cerebellar networks and connectivity in early MS. METHODS: We used diffusion spectrum and resting-state functional MRI (rs-fMRI) to establish the structural and functional cerebellar connectomes in 28 early relapsing-remitting MS patients and 16 healthy controls (HC). We performed multicontrast "connectometry" by quantifying multiple MRI parameters along the structural tracts (generalized fractional anisotropy-GFA, T1/T2 relaxation times and magnetization transfer ratio) and functional connectivity measures. Subsequently, we assessed multivariate differences in local connections and network properties between MS and HC subjects; finally, we correlated detected alterations with lesion load, disease duration, and clinical scores. RESULTS: In MS patients, a subset of structural connections showed quantitative MRI changes suggesting loss of axonal microstructure and integrity (increased T1 and decreased GFA, P < 0.05). These alterations highly correlated with motor, memory and attention in patients, but were independent of cerebellar lesion load and disease duration. Neither network organization nor rs-fMRI abnormalities were observed at this early stage. CONCLUSION: Multicontrast cerebellar connectometry revealed subtle cerebellar alterations in MS patients, which were independent of conventional disease markers and highly correlated with patient function. Future work should assess the prognostic value of the observed damage. Hum Brain Mapp 36:1609-1619, 2015. © 2014 Wiley Periodicals, Inc.

Recueil de jurisprudence annuelle et spéciale concernant les huissiers

1820 (T1,ED2).

Recueil de législation & jurisprudence coloniales / dir. P. Dareste ; dir. G. Appert

1898/01 (A1,T1,N1)-1898/02.

Recueil de lois, ordonnances, décrets, réglements et circulaires concernant les différents services du Ministère des travaux publics : ancien Recueil Potiquet / dressé par les soins de l'Administration centrale

1399 (SER1,T1)-1804.

Recueil de lois, ordonnances, décrets, réglements et circulaires concernant les différents services du Ministère des travaux publics : ancien Recueil Potiquet / dressé par les soins de l'Administration centrale

1881 (SER2,T1)-1882.

Recueil de lois, ordonnances, décrets, réglements et circulaires concernant les différents services du Ministère des travaux publics : ancien Recueil Potiquet / dressé par les soins de l'Administration centrale

1936 (TB,T1).

Recueil des arrêts de la cour des comptes commentés et annotés

1911/01 (A1,T1)-1911/12.

La Réforme industrielle ou le Phalanstère : journal proposant la fondation d'une phalange, réunion de 1100 personnes associées en travaux de culture, fabrique et ménage / [dir. Charles Fourier]

1832/06/01 (T1,N1)-1834/02/28 (T2,N39).

Répertoire périodique de l'enregistrement : recueil de toutes les décisions administratives et judiciaires sur l'enregistrement et le timbre, comparées avec le droit civil...

1854 (T1).

La Révolution française : revue historique...

1881 (T1)-1890 (T18).

La Révolution française : revue historique...

1881/07 (T1)-1881/12.

La Révolution française : revue historique...

Périodicité : Mensuel ; trimestriel

Revue antimaçonnique / directeur : commandant Cuignet

1915/09 (A6,N9 = SER2,T1)-1915/10 (A6,N10).