949 resultados para congenital heart malformation


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Obesity is a worldwide problem, not just an issue for industrialized nations. Therefore, we need to examine opportunities for prevention and treatment from a global perspective.

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The possible shortage of applicants for principal positions is news in both Australia and abroad. We subject a corpus of predominantly US news article to deconstructive narrative analysis and find that the dominant media representation of principals' work is one of long hours, low salary, high stress and sudden death from high stakes accountabilities. However reported US policy interventions focus predominantly on professional development for aspirants. We note that this will be insufficient to reverse the lack of applications, and suggest that the dominant media picture of completely unattractive principals' work, meant to leverage a policy solution will perhaps paradoxically perpetuate the problem. This picture is also curiously at odds with research that reports high job satisfaction among principals. We suggest that there is a dominant binary of victim and saviour principal in both media and policy which prevents some strategic re-thinking about how the principalship might be different.

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Inflammatory markers, including serum C-reactive protein (CRP), are predictors of coronary heart disease (CHD) in adults. South Asians in the UK have higher rates of CHD in adulthood than national rates.We tested the hypotheses that South Asian infants would have higher serum concentrations of CRP and homocysteine than European infants up to 2 years of age and that higher infant weight is associated with elevation of inflammatory markers. Infants of South Asian and European origin were investigated in a mixed cross sectional-longitudinal cohort study. Mothers were recruited ante-natally from St Mary’s Hospital,Manchester by postal invitation and telephone call to non-responders. Infants with metabolic or congenital abnormalities, known syndromes or pre-maturity were excluded. Measurements were collected at birth and either 3, 6, 12 or 24 months. High sensitivity CRP and homocysteine were measured by an immulite immunoassay. We used mixed linear modelling to assess whether infant weight, ethnicity, length of follow-up or their interaction were associated with inflammatory makers in infants during follow-up. Data are presented on 306 infants (109 South Asian and 197 European). We found that European infants had higher serum CRP than South Asian infants during follow-up which was of borderline significance.There was no difference in serum homocysteine between ethnic groups during followup and no significant interaction between ethnicity and follow-up. Infant weight was significantly associated with CRP but not homocysteine. In this ongoing longitudinal study,we found little difference in inflammatory markers in infants from birth to 2 years despite markedly higher rates of CHD in South Asian than European adults. Life course exposure to risk factors may play a more dominant role in the development of CHD.