Sustainable human settlements development in Latin America and the Caribbean

Includes bibliography

El desarrollo sostenible de los asentamientos humanos en América Latina y el Caribe

Incluye Bibliografía

Changing presentation of complete hydatidiform mole at the New England Trophoblastic Disease Center over the past three decades: does early diagnosis alter risk for gestational trophoblastic neoplasia?

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

HIGHLIGHTS OF BIRD CONTROL RESEARCH IN ENGLAND, FRANCE, HOLLAND, AND GERMANY

The purpose of this paper is to present a brief review of the research being conducted in England, France, Germany, and The Netherlands on problems caused by nuisance and depredating birds. Much of the information presented has been obtained through correspondence with collaborators. In the fall of 1962, I discussed depredating bird and bird-airport problems with research workers in these countries, and also attended the meeting of the International Union of Applied Ornithology held in Frankfurt/Main. In November 1963, I attended an international symposium about the bird-airport problem, held in Nice, France. This paper will draw attention to the current research which I think will interest American investigators, but will not report every aspect of the foreign investigations. Details appear in the publications that are listed.

The Impact of Regulatory Heterogeneity on Agri-food Trade

We estimate the impact of regulatory heterogeneity on agri-food trade using a gravity analysis that relies on detailed data on non-tariff measures (NTMs) collected by the NTM-Impact project. The data cover a broad range of import requirements for agricultural and food products for the EU and nine of its major trade partners. We find that trade is significantly reduced when importing countries have stricter maximum residue limits (MRLs) for plant products than exporting countries. For most other measures, due to their qualitative nature, we were unable to infer whether the importer has stricter standards relative to the exporter, and we do not find a robust relationship between these measures and trade. Our findings suggest that, at least for some import standards, harmonising regulations will increase trade. We also conclude that tariff reductions remain an effective means to increase trade even when NTMs abound.

Multicentric Carpotarsal Osteolysis Is Caused by Mutations Clustering in the Amino-Terminal Transcriptional Activation Domain of MAFB

Multicentric carpotarsal osteolysis (MCTO) is a rare skeletal dysplasia characterized by aggressive osteolysis, particularly affecting the carpal and tarsal bones, and is frequently associated with progressive renal failure. Using exome capture and next-generation sequencing in five unrelated simplex cases of MCTO, we identified previously unreported missense mutations clustering within a 51 base pair region of the single exon of MAFB, validated by Sanger sequencing. A further six unrelated simplex cases with MCTO were also heterozygous for previously unreported mutations within this same region, as were affected members of two families with autosomal-dominant MCTO. MAFB encodes a transcription factor that negatively regulates RANKL-induced osteoclastogenesis and is essential for normal renal development. Identification of this gene paves the way for development of novel therapeutic approaches for this crippling disease and provides insight into normal bone and kidney development.