Short interspersed CAN SINE elements as prognostic markers in canine mammary neoplasia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Modified routine for decreasing numeric oscillations at associations of lumped elements

Some changes in the application of the numeric trapezoidal integration are analyzed for applications considering pi circuits. It is considered numeric and computational proceedings for improving the numeric results obtained with associations of pi circuits. In numeric integration solutions of the linear systems, it is common to represent these associations of pi circuits by only one matrix. This representation introduces undesirable numeric oscillations in simulations of the dynamics of wave propagation in electrical systems. The proposed changes improve the results of application of cascades of pi circuits associated to the trapezoidal integration, avoiding that the numerical oscillations, or Gibb's oscillations, have high values and are slowly damped. For the carried out simulations, different number of pi circuits and voltage sources are checked, confirming the reduction of the influence of the numeric oscillations on the obtained results. (C) 2014 Elsevier B.V. All rights reserved.

Three-dimensional analysis of reinforced concrete members via embedded discontinuity finite elements

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Modeling of multiple cracks in reinforced concrete members using solid finite elements with high aspect ratio

This paper presents a new technique to model interfaces by means of degenerated solid finite elements, i.e., elements with a very high aspect ratio, with the smallest dimension corresponding to the thickness of the interfaces. It is shown that, as the aspect ratio increases, the element strains also increase, approaching the kinematics of the strong discontinuity. A tensile damage constitutive relation between strains and stresses is proposed to describe the nonlinear behavior of the interfaces associated with crack opening. To represent crack propagation, couples of triangular interface elements are introduced in between all regular (bulk) elements of the original mesh. With this technique the analyses can be performed integrally in the context of the continuum mechanics and complex crack patterns involving multiple cracks can be simulated without the need of tracking algorithms. Numerical tests are performed to show the applicability of the proposed technique, studding also aspects related to mesh objectivity.

Chromosomal mapping of two Mariner-like elements in the grasshopper Abracris flavolineata (Orthoptera: Acrididae) reveals enrichment in euchromatin

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

From archives to archival science Elements for a discursive construction

This work tries to outline the theoretical background established by archival science manuals, based mainly on discourse analysis as a key discipline to understand which the differences are and points of conceptual commonality in archival science traditions studied that to some extent, are additional. As archival science is a product of historically constructed knowledge, the context of conceptual production ultimately reflects in the different schools of thought and in the methodological approach. The manuals discussed here were selected by their canon and their wide dissemination in the archival science field, and are: the Manual for the arrangement and description of archives of the Association of Dutch Archivists (1898), and Jenkinson's A manual of archive administration including the problems of war archives and archive making. We considered how in these manuals two key concepts are discussed as for organization methodology in archival science: description and classification, establishing, from these concepts, which are the intertwined discourses in these texts and relating them to their historical aspects.

Complex modal analysis of a slender vertical rotor by finite elements method

In this paper, natural frequencies were analyzed (axial, torsional and flexural) and frequency response of a vertical rotor with a hard disk at the edge through the classical modal and complex analysis. The equation that rules the movement was obtained through the Lagrangian formulation. The model considered the effects of bending, torsion and axial deformation of the shaft, besides the gravitational and gyroscopic effects. The finite element method was used to discretize the structure into hollow cylindrical elements with 12 degrees of freedom. Mass, stiffness and gyroscopic matrices were explained consistently. The classical modal analysis, usually applied to stationary structures, does not consider an important characteristic of rotating machinery which are the methods of forward and backward whirl. Initially, through the traditional modal analysis, axial and torsional natural frequencies were obtained in a static shaft, since they do not suffer the influence of gyroscopic effects. Later research was performed by complex modal analysis. This type of tool, based on the use of complex coordinates to describe the dynamic behavior of rotating shaft, allows the decomposition of the system in two submodes, backward and forward. Thus, it is possible to clearly visualize that the orbit and direction of the precessional motion around the line of the rotating shaft is not deformed. A finite element program was developed using MATLAB (TM) and numerical simulations were performed to validate this model. Natural frequencies and directional frequency forced response (dFRF) were obtained using the complex modal analysis for a simple vertical rotor and also for a typical drill string used in the construction of oil wells.

Tropical Africa as a cradle for horizontal transfers of transposable elements between species of the genus Drosophila and Zaprionus

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Key participants of the tumor microenvironment of the prostate: An approach of the structural dynamic of cellular elements and extracellular matrix components during epithelial-stromal transition

Cancer is a multistep process that begins with the transformation of normal epithelial cells and continues with tumor growth, stromal invasion and metastasis. The remodeling of the peritumoral environment is decisive for the onset of tumor invasiveness. This event is dependent on epithelial–stromal interactions, degradation of extracellular matrix components and reorganization of fibrillar components. Our research group has studied in a new proposed rodent model the participation of cellular and molecular components in the prostate microenvironment that contributes to cancer progression. Our group adopted the gerbil Meriones unguiculatus as an alternative experimental model for prostate cancer study. This model has presented significant responses to hormonal treatments and to development of spontaneous and induced neoplasias. The data obtained indicate reorganization of type I collagen fibers and reticular fibers, synthesis of new components such as tenascin and proteoglycans, degradation of basement membrane components and elastic fibers and increased expression of metalloproteinases. Fibroblasts that border the region, apparently participate in the stromal reaction. The roles of each of these events, as well as some signaling molecules, participants of neoplastic progression and factors that promote genetic reprogramming during epithelial–stromal transition are also discussed.

Terminal-repeat retrotransposons with GAG domain in plant genomes: a new testimony on the complex world of transposable elements

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Correlations among antiangiogenic factors and trace elements in hypertensive disorders of pregnancy

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Opportunistic pathogens and elements of the resistome that are common in bottled mineral water support the need for continuous surveillance

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Thoron and radon activity concentration in mineral waters of spas from southeastern Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Frugivores at higher risk of extinction are the key elements of a mutualistic network

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)