Um Modelo Espacial para a Resposta Imunológica Adaptativa da Hepatite B

This paper proposed a two-dimensional spatial model to describe the adaptive immune response for viral hepatitis B. This model considered six populations: healthy hepatocytes T, infected hepatocytes Y , hepatitis B virus V , innate immune system I, active immune system X and memory cells, X. First, a compartmental model was constructed and its equilibrium solutions and also the threshold values related to the stability of each solution were obtained. Using this model, we was able to reproduce the different trends observed for the disease, which are: individuals that eliminate the infection without forming immune response, patients with acute and chronic carriers. By including dispersion of defense cells of the immune system and virus (spatial model), we analyze two situations: homogeneous model, in which the model parameters are the same at all points of the network, and heterogeneous model, which characterizes cells more permeable and less permeable to virus invasion. For the two spatial models (homogeneous and heterogeneous) the times relatead to the viral erradication and/or virus invasion and persistence becoming smaller in relation to the compartmental model. The results also showed that for the set of values used in the simulations and if the two diffusion rates are different from zero, the model is sensitive to variations in the rate of viral spread and not dependent on the dispersion of memory cells. Finally, the heterogeneous model when compared to the homogeneous model shows that the infection can be spatially limited depending on the type of the cell involved in the infection process

Modelagem de motor de combustão internae simulação do processo de queima de combustível

The internal combustion engine is a heat engine widely used in the automotive industry. In order to better understand its behavior many models in the literature have been proposed in the last years. The 0-D thermodynamic model is a fairly simple tool but it is very useful to understand the phenomenon of combustion inside the chamber of internal combustion engines. In the first phase of this work, an extensive literature review was made in order to get information about this kind of analysis and, after this, apply them in a model able to calculate the instantaneous temperature and pressure in one zone of the combustion chamber of a diesel engine. Therefore some considerations were made with the aim of increasing the accuracy of the model in predicting the correct behavior of the engine, adding the combined effects of heat transfer, leakage and injection. In the second phase, the goal was to study the internal flow of a three-dimensional model of an internal combustion engine. In order to achieve this goal the software Solidworks was used to create the geometries of an engine and the suite of softwares Ansys was used to create the moving mesh (ICEM CFD and CFX-Pre) and to solve the CFD problem (Ansys CFX code). The model was able to perform the air flow simulation during the four-stroke cycle of an engine: admission, compression, expansion and exhaust. The results obtained from both models were suitable and they open a new range of possibilities for future researches on the field

O processo de configuração curricular: uma análise da compreensão de professores de educação física das séries iniciais do ensino fundamental

Pós-graduação em Educação - IBRC

Modelo experimental de conjuntivite alérgica: efeito do tratamento farmacológico com a proteína anti-inflamatória galectina - 1

Pós-graduação em Genética - IBILCE

Os desdobramentos e conflitos da criação do Parque Estadual Ilha do Cardoso sob a ótica do modelo GTP (Geossistema – Território- Paisagem)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Utilização do modelo da barganha de Nash na seleção de carteiras

This paper discussed the model of Nash bargaining (NASH, 1950, 1953), which its arbitration function is invariant for the linear transformations. A more robust model was proposed with respect to the incommensurable effect. The result obtained by the optimization process was not influenced by the units or the amplitude values of these measures. The risk and the return is measured in portfolios of assets and defined a risk metric, return and a method to handle the risk and return. For this, we made a review on the main characteristics of Brazilian industry funds and their evolution over the past years, in addition to treating on the risk in the financial market, the importance of portfolio selection and the Markowitz Model. Are made closing remarks, an analysis of the results, some suggests, concerns and how such concerns can be improved and / or explored in future studies

Modelo de avaliação de impacto ambiental utilizando a teoria dos conjuntos fuzzy: um estudo de caso para a indústria automobilística

Pós-graduação em Ciências Ambientais - Sorocaba

Um modelo de avaliação interna para a melhoria de processos pedagógicos e administrativo: aplicação em uma faculdade de tecnologia

Pós-graduação em Engenharia Mecânica - FEG

Equações de Painlevé mistas e modelo PIII-PV simétrico

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Desenvolvimento da Suécia durante os Anos dourados do Capitalismo: fatores históricos, ascensão do Welfare State, influências de Gunnar Myrdal e o modelo Rehn-Meidner

A Suécia está entre os países desenvolvidos que mais obtiveram êxito na construção do seu Estado de Bem-Estar Social (Welfare State). Esta instituição amadureceu durante os Anos Dourados do Capitalismo (1945 - 1975). O sucesso na sua construção pode estar ligado a uma série de fatores, como: o contexto internacional de Bretton Woods; as raízes históricas do país, com suas especificidades institucionais, econômicas e sociais; a atuação do Partido Social Democrata sueco, que contou com a participação de Gunnar Myrdal, um grande pensador econômico e um dos maiores teóricos referentes ao Welfare State; o Modelo Rehn-Meidner, que foi elaborado na década de 1950 e visou crescimento econômico, pleno emprego, controle inflacionário e equalização da renda simultaneamente através de políticas macroeconômicas contracionistas, Políticas Ativas no Mercado de Trabalho e Política de Salário Solidário. Dado tudo isto, o objetivo desta pesquisa é entender o processo de desenvolvimento do país e do seu Welfare State, analisando as medidas adotadas no período de 1950 a 1975, com particular interesse em identificar as possíveis influências que o Modelo Rehn-Meidner e o pensamento econômico e político de Gunnar Myrdal tiveram na escolha das políticas que contribuíram para o desenvolvimento do país. Além disso, será analisado o ambiente internacional da época, bem como a História da Suécia, com a finalidade de identificar se e como outros fatores contribuíram para o desenvolvimento socioeconômico da Suécia e do seu Estado de Bem-Estar Social

Preparação de nanofio via deposição eletroquímica utilizando modelo de membrana porosa

From the last decade of the twentieth century, the rapid growth of nanotechnology has resulted in the discovery of a number of forms of nanoparticles and nanoclusters. We can cite as an example: nanotubes, nanowires, nanobelts, and nanoconesnanoclusters which have a wide range of applications, particularly as catalysts magnetic material nanodevices, chemical sensors, degradation of toxic chemicals, or even as possible carriers for the isotope medical applications.. The first step is the production and characterization of nanowires multithreaded using different types of metals (nickel, silver, gold) and polymers (pyrrole), which are prepared by electrochemical deposition process. Will be held by the characterization of the same images of scanning electron microscopy (SEM) and transmission electron microscopy (TEM)

Avaliação da remoção de sulfametoxazol, diclofenaco e 17β-estradiol em água por meio de processo oxidativo com cloro

Pós-graduação em Engenharia Civil - FEIS

Diagnóstico do nível de maturidade do processo de desenvolvimento de produtos: um estudo de caso em empresa calçadista

The process of product development (PPD) is a strategic factor in which companies seek to identify consumer needs. The relationship of the practices adopted, tools, techniques, among others, can determinate the maturity level of the company in this process. The purpose of this paper is to understand and diagnose the level of maturity of the PDP in footwear segment industry. For the case study, a company inserted into one of the largest poles of women’s footwear in Brazil, located in Jaú, São Paulo State, was researched. The diagnosis is based on the maturity levels of the unified model, reference in the process of product development, proposed by Rozenfeld et al. (2006). The application of the model assisted to diagnose the current maturity level of the company in this process, providing useful information to achieve higher levels of maturity in the PDP.

Modelo de mensuração orçamentária dos custos de produção para uma indústria de manufatura de madeira

The companies who produce goods and services taking of the demanding of the customers correctly use the management of the production. The verification of the costs decisive becomes. This article presents a model of measurement of the results of production for the elaborated budgetary planning for an industry of wooden manufacture. This research intends to evidence the importance of the planning and the budget. It presents main given the necessary ones to the budgetary methods, which are used by the company as instruments of control of the planning, providing the concentration of the efforts of the managers in the point-key, minimizing the tension in the process of decision taking.

Gestão da atividade física no SUS: o processo de inserção do Programa de Exercícios Físicos em Unidades de Saúde no município de Rio Claro-SP : um estudo de caso

Pós-graduação em Ciências da Motricidade - IBRC