Estudo de um caso de tratamento de câncer com um produto alternativo às técnicas convencionais

This work consists of a case study, a qualitative methodology, which aims to show the effects of TIVALLEC, a supplement in vitamins, as an alternative treatment of cancer. This study had also the objective of evaluating one patient’s quality of life thirteen years after being diagnosed with an advanced prostate cancer, and having decided for an alternative treatment using TIVALLEC instead of conventional treatments, having obtained excellent results. An open interview was conducted with patient, evaluating various aspects of his life after the initial diagnosis and the chosen treatment. The answers were transcribed after being limitedly edited for readability. At the end of the study, with the support of recent literature, the interview allowed the conclusion that TIVALLEC was greatly effective, creating good quality of life and wellness for the patient during all the period of thirteen year after the diagnosis up to now. These alternative treatment results may be seen as demanding new studies to help cancer patients who embrace or not the conventional treatments

Estudo de caso: formulação de custo de um produto de usinagem em uma pequena empresa

Many variables are indirectly involved in the transformation of raw material into a metallurgical industry, such as machine hours, hours of hand labor directly and / or indirect, setup time, etc. This research focuses on the complexity of formulating the cost of metallurgical products, based on a case study, in which one has incurred a large loss on the sale of a product called Punch. The main objective of this work is to define the variables of the cost of members and other metallurgical products, so simplified general, checking what were the failures costing the case studied, in order to help others. The method of formulating cost was determined as recommended by SEBRAE guidance for small businesses. The results showed a loss R$ 13.201,00 in the batch of 15 units of punch. Possible improvements have been identified for reducing the production cost

Proposta de traçado de alcoolduto ligando a hidrovia Tietê Paraná à refinaria do planalto paulista com uso de avaliação multicritérios e geotecnologias

From the beginning of the century, with the advent of the flex fuel car, successor fluctuations in oil prices and the rise of awareness of the impending shortage of fossil fuels, the alcohol sector begins to reappear in the panorama of national economy making Brasill reaches the point of becoming a leading exporter of this product. Ethanol assumed the role of such importance in Brazilian exports, which Petrobras through the Growth Acceleration Program (PAC) has made investments in the Brazilian pipeline network to better ensure the production of ethanol to major ports. The means of transport in pipelines are safe and inexpensive, but require careful evaluation in its implementation, they may lead to negative social and environmental impacts. Thus, the purpose of this project is to propose the best route for an ethanol pipeline connectin the Tietê-Paraná, leaving the municipality of Santa Maria da Serra (SP), to the Planalto Paulista Refinery (REPLAN), located in Paulinia (SP), belonging to the passage of ethanol export corridor, currently under revelopment. The technique used for the development of the stroke is the association of multicriteria evaluation, the geographical information system (SIG) and geotechnologies. This study presented three possible layouts for the ethanol pipeline, highlighting the best option, in addition, demonstrated the suitability of the area to receive projects of similar nature to a pipeline

Avaliação e comparação do perfil de dissolução do Fluconazol 150mg cápsulas produto referência, genérico e similar

Fármacos com alta permeabilidade intestinal, ampla faixa terapêutica e ausência de evidências documentadas de bioinequivalência ou problemas de biodisponibilidade devido à formulação, foram considerados bioisentos pela ANVISA (RDC 37/2011), ou seja, os fármacos que se encaixam nesta categoria não necessitam de estudos de biodisponibilidade relativa/bioequivalência para serem comercializados. Dentre os catorze produtos que receberam a bioisenção da ANVISA, encontra-se o fluconazol, antifúngico aprovado atualmente para ser comercializado em vários países, inclusive no Brasil, onde inúmeras opções comerciais do produto fluconazol cápsulas, genérico ou similar, podem ser adquiridas. Tendo em vista a bioisenção do produto fluconazol cápsulas e sua larga utilização no mercado brasileiro, o estudo do perfil de dissolução deste produto torna-se relevante. Sendo assim, este trabalho avaliou 2 produtos genéricos e 2 produtos similares frente ao medicamento referência em relação aos seus perfis de dissolução e a similaridade entre eles. Os resultados foram avaliados seguindo a RDC 31/2011 da ANVISA que prevê o cálculo do fator de similaridade entre os perfis de dissolução. E, pôde-se observar que apenas 1 medicamento genérico apresentou o fator de similaridade adequado (entre 50 e 100), sendo 51,60, os demais medicamentos testes apresentaram valores fora do intervalo adotado pela ANVISA. Através desses resultados, conclui-se que intercambialidade do medicamento referência pelo medicamento genérico ou similar não é adequada, uma vez que eles não são considerados iguais, salvo um dos medicamentos genéricos.

Consumo e incorporação de água na produção de commodities brasileiras

Water is one of the main inputs in agribusiness and is traded indirectly through the sale of agricultural products such as orange (juice or fresh) and cane sugar (ethanol and refined sugar). This study aims to estimate the proportional mass of water present in the products exported in the form of agricultural commodities considering the amount of water incorporated into the product in its genesis by plant photosynthesis, reinforcing a reflection on virtual and real water export, as well to indicate subsidies to management, planning and taxing of water resources

A aplicação da teoria do lean seis sigma na prestação de serviços no setor agrícola

This thesis aims to analyze the applicability of Lean Six Sigma and DMAIC to improve processes focused on agriculture. We discuss the origins of each system separately, Lean Manufacturing, the Toyota plants in Japan, and Six Sigma, by Motorola in the U.S., and then appears to merge them and can meet their complementarities and synergy between their tools. Finally, we describe a case study focused on the harvesting department, applicable to all types of manuals crops, covering the production of fruits, vegetables and greens. This study shows the ability to reduce costs, increase productivity and elimination of defects that the methodology developed with the fusion of Lean Manufacturing with Six Sigma allows

Implementação de FMEA em uma linha de produção de caminhonetes

Currently the quality of a final product is as important as the price they pay for it, to the satisfaction of having something durable and exercising its function as well as has been informed. This work aims to define the stages of the process of implementing a new project in a production line in order to ensure product quality and process, defining each step with those responsible for each area of the factory, implementing new tools and methods, improving process with lessons learned from previous projects, gathering information on the production line to analyze the need for rigorous controls to prevent errors. With the definition of schedule after studies of the plant where the new project was implemented, establish the goals of each phase to ensure the quality of process and product

O léxico da apicultura e da melinponicultura no Brasil: limites e flexibilidade para sua fixação em um dicionário terminológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Cor do solo na caracterização de áreas específicas de manejo para cultura do café

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Microbiota contaminante em bebidas lácteas fermentadas comerciais

Lately, the acceptability of fermented dairy beverages has been increased, due to the nutritional benefits, the practical consumption and the low cost of product for the manufacturers, and consequently for final market price to the consumers. During the manufacturing process, these products can be susceptible to microbiological contamination. The present study investigated the contaminant microbiota in fermented dairy beverages produced by small- and medium-sized companies, by means of analyses on moulds and yeasts counting, determination of the Most Probable Number (MPN) of total and thermo tolerant coliforms, Escherichia coli and Salmonella spp. detection, and determination of pH value. In spite of the absence of Salmonella spp., a high counts of yeasts and moulds were found, and E. coli was detected in five samples (16.67 %); and the sample were classified as “products in poor sanitary conditions”, because they showed thermo-tolerant coliforms counting higher than the standard established by the legislation in force. Therefore, quality programs such as Good Manufacturing Practices (GMP) and Hazard Analysis and Critical Control Points (HACCP) should be employed to prevent any contamination risk, in order to provide safe products to consumers.

Qualidade microbiológica de bebidas lácteas fermentadas, com adição de polpas de frutas, comercializadas na região de São José do Rio Preto, SP.

As bebidas lácteas fermentadas são produtos formulados contendo iogurte, soro de leite, polpa de frutas, além de outras matérias-primas e aditivos permitidos. O produto final deve apresentar os micro-organismos de forma viável e abundante. Sua popularidade vem aumentando significativamente, principalmente devido aos seus benefícios nutricionais, ao menor custo do produto para o fabricante, à redução do preço final para o consumidor e por apresentar baixa viscosidade, sendo consumida como bebida suave e refrescante. Apesar do processo de fabricação ser considerado simples, utilizando-se principalmente os equipamentos disponíveis nas indústrias lácteas, estes produtos podem estar sujeitos à contaminação microbiana, quando não atendidas as condições elementares de higiene e sanidade. Tal contaminação pode ser representada por leveduras, coliformes totais, termotolerantes e bolores. Considerando os aspectos mencionados, o objetivo deste trabalho foi avaliar a qualidade microbiológica de bebidas lácteas fermentadas, com adição de polpas de frutas, comercializadas na região de São José do Rio Preto û SP, por meio das seguintes análises microbiológicas: contagem de bolores e leveduras, determinação do Número Mais Provável (NMP) de coliformes totais, temotolerantes e pesquisa de Escherichia coli e de Salmonella spp. Foi ainda efetuada a determinação do pH eletrométrico. Após a obtenção dos resultados verificou-se que 20% das amostras analisadas não atenderam ao padrão microbiológico estabelecido na legislação vigente, para coliforme termotolerentes, evidenciando positividade na pesquisa de Escherichia coli, sendo por este motivo, considerados como produtos em condições sanitárias insatisfatórias, portanto, produtos impróprios para o consumo humano.(AU)

Decisão making or buying: uma aplicação em células de manufatura de uma indústria de produção mecânica

In order to maintain the competitiveness the companies seek for cost reduction and resource optimization. A product or service price is calculated considering direct and indirect costs involved in its fabrication, which means that if an intern indirect process is optimized, the final price of the product is also reduced and becomes more interesting to the final costumer. Considering this reasoning, the companies must evaluate each of their processes and optimize them. It is common to outsource intern products manufacturing as a cost reduction strategy, nevertheless when there are already resources and capability to produce the own goods, it becomes necessary to evaluate the economic gain that each strategy - make or buy - generates. This paper aims to evaluate the necessary support to take a decision regarding making or buying in a production cell of hoses based in the value of economic cost, system cost and decision process

Localização e preço de contrato ótimo da geração distribuída em sistemas de distribuição radiais de energia elétrica

Pós-graduação em Engenharia Elétrica - FEIS

Potencial de uso agrícola de levedura seca inativa de cana-de-açúcar e de resíduos orgânicos

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Modernização agrícola e a região da Alta Mogiana Paulista: análise da expansão da produção de cana-de-açúcar em uma tradicional região cafeeira

Pós-graduação em Geografia - IGCE