987 resultados para Motoneuron Pool
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In this paper, we study a k-out-of-n system with single server who provides service to external customers also. The system consists of two parts:(i) a main queue consisting of customers (failed components of the k-out-of-n system) and (ii) a pool (of finite capacity M) of external customers together with an orbit for external customers who find the pool full. An external customer who finds the pool full on arrival, joins the orbit with probability and with probability 1− leaves the system forever. An orbital customer, who finds the pool full, at an epoch of repeated attempt, returns to orbit with probability (< 1) and with probability 1 − leaves the system forever. We compute the steady state system size probability. Several performance measures are computed, numerical illustrations are provided.
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The hazards associated with major accident hazard (MAH) industries are fire, explosion and toxic gas releases. Of these, toxic gas release is the worst as it has the potential to cause extensive fatalities. Qualitative and quantitative hazard analyses are essential for the identitication and quantification of the hazards associated with chemical industries. This research work presents the results of a consequence analysis carried out to assess the damage potential of the hazardous material storages in an industrial area of central Kerala, India. A survey carried out in the major accident hazard (MAH) units in the industrial belt revealed that the major hazardous chemicals stored by the various industrial units are ammonia, chlorine, benzene, naphtha, cyclohexane, cyclohexanone and LPG. The damage potential of the above chemicals is assessed using consequence modelling. Modelling of pool fires for naphtha, cyclohexane, cyclohexanone, benzene and ammonia are carried out using TNO model. Vapor cloud explosion (VCE) modelling of LPG, cyclohexane and benzene are carried out using TNT equivalent model. Boiling liquid expanding vapor explosion (BLEVE) modelling of LPG is also carried out. Dispersion modelling of toxic chemicals like chlorine, ammonia and benzene is carried out using the ALOHA air quality model. Threat zones for different hazardous storages are estimated based on the consequence modelling. The distance covered by the threat zone was found to be maximum for chlorine release from a chlor-alkali industry located in the area. The results of consequence modelling are useful for the estimation of individual risk and societal risk in the above industrial area.Vulnerability assessment is carried out using probit functions for toxic, thermal and pressure loads. Individual and societal risks are also estimated at different locations. Mapping of threat zones due to different incident outcome cases from different MAH industries is done with the help of Are GIS.Fault Tree Analysis (FTA) is an established technique for hazard evaluation. This technique has the advantage of being both qualitative and quantitative, if the probabilities and frequencies of the basic events are known. However it is often difficult to estimate precisely the failure probability of the components due to insufficient data or vague characteristics of the basic event. It has been reported that availability of the failure probability data pertaining to local conditions is surprisingly limited in India. This thesis outlines the generation of failure probability values of the basic events that lead to the release of chlorine from the storage and filling facility of a major chlor-alkali industry located in the area using expert elicitation and proven fuzzy logic. Sensitivity analysis has been done to evaluate the percentage contribution of each basic event that could lead to chlorine release. Two dimensional fuzzy fault tree analysis (TDFFTA) has been proposed for balancing the hesitation factor invo1ved in expert elicitation .
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The SST convection relation over tropical ocean and its impact on the South Asian monsoon is the first part of this thesis. Understanding the complicated relation between SST and convection is important for better prediction of the variability of the Indian monsoon in subseasonal, seasonal, interannual, and longer time scales. Improved global data sets from satellite scatterometer observations of SST, precipitation and refined reanalysis of global wind fields have made it possible to do a comprehensive study of the SST convection relation. Interaction of the monsoon and Indian ocean has been discussed. A coupled feedback process between SST and the Active-Break cycle of the Asian summer monsoon is a central theme of the thesis. The relation between SST and convection is very important in the field of numerical modeling of tropical rainfall. It is well known that models generally do very well simulating rainfall in areas of tropical convergence zones but are found unable to do satisfactory simulation in the monsoon areas. Thus in this study we critically examined the different mechanisms of generation of deep convection over these two distinct regions.The study reported in chapter 3 has shown that SST - convection relation over the warm pool regions of Indian and west Pacific oceans (monsoon areas) is in such a way that convection increases with SST in the SST range 26-29 C and for SST higher than 29-30 C convection decreases with increase of SST (it is called Waliser type). It is found that convection is induced in areas with SST gradients in the warm pool areas of Indian and west Pacific oceans. Once deep convection is initiated in the south of the warmest region of warm pool, the deep tropospheric heating by the latent heat released in the convective clouds produces strong low level wind fields (Low level Jet - LLJ) on the equatorward side of the warm pool and both the convection and wind are found to grow through a positive feedback process. Thus SST through its gradient acts only as an initiator of convection. The central region of the warm pool has very small SST gradients and large values of convection are associated with the cyclonic vorticity of the LLJ in the atmospheric boundary layer. The conditionally unstable atmosphere in the tropics is favorable for the production of deep convective clouds.
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While the seriousness of the problem of antibiotic resistance is now recognized, the complex web of resistance linking humans, animals, and the environment is getting realized. More often, antibiotics are used as a preventive measure against diseases. Antibiotic use for agriculture leads to the increased resistance in the environment since antibiotics are inevitable element during agriculture/aquaculture and antibiotic residues are excreted as waste that is frequently spread onto farmland as organic fertilizer. Fecal bacteria survive long periods in the environment and spread through runoff into groundwater, rivers, and marine ecosystems.However, horizontal gene transfer occurs in the animals and guts of humans and in a variety of ecosystems, creating a pool of resistance in the rice fields and open waters. Even if people are not in direct contact with resistant disease through food animals, there are chances of contact with resistant fecal pathogens from the environment. Additionally, pathogens that are autochthonous to the environment can acquire resistance genes from the environment. Our study revealed that autochthonous , bacteria Vibrio spp gained antibiotic resistance in the environment. Further, it was evident that horizontal gene transfer occurs in Vibrio by means of plasmids, which further augments the gravity of the problem. Non-pathogenic bacteria may also acquire resistance genes and serve as a continuing source of resistance for other bacteria, both in the environment, and in the human gut. As the effectiveness of antibiotics for medical applications decline, the indiscriminate use of in aquaculture and in humans can have disastrous conditions in future due to horizontal gene transfer and the spread of resistant organisms: We must recognize and deal with the threat posed by overuse of antibiotics.
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The present study revealed the importance of marine actinomycetes as a potent source of bio active secondary metabolites. The selected isolates were capable of protecting Peaneus monodon against WSSV infection. They also proved to be inhibitory to vibrios and is a rich pool of hydrolytic enzymes. Their capacity to proliferate in saline environments and their property of non-pathogenicity to prawns makes them good candidates to be applied as probionts in penaeid shrimp aquaculture. They also enhanced the immune status of shrimps challenged with WSSV and act as a good source of antioxidants. Exploitation of the potential for the prophylactic and therapeutic measures in aquatic animal health management would be highly rewarding. This work is a preliminary study targeting marine actinomycetes as a source of antiviral compounds and as probionts in Penaeus monodon culture systems. More work is needed to understand the nature and mode of action of the bioactive compound, the various aspects of immune and antioxidant responses under challenge and when exposed to pro active treatments, and the dose and frequency of application of such compounds under rearing conditions.
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This thesis entitled spatial and temporal variarion of microbial community structure in surficial sediments of cochin estuary.In the estuarine and coastal systems, organic matter (OM) is derived not only from autochthonous primary production, but also from allochthonous (terrestrial) organic matter (OM) delivered by river discharge and runoff. A significant portion of the OM sinks through the water column and is ultimately stored in carbon pool in the sediments.Analysis of spatial and temporal variation in benthic microbial community of a tropical estuary was conducted for the first time using non selective measures that affirms that PLFA approach is a sensitive and reliable method in determining microbial community structures of surficial sediments of estuary.The close relationship between the concentrations of the microbial fatty acids and total biomass indicates that bacteria could account for the largest proportion of the biomass in the sediments.This is first study that has documented the changes in microbial community composition linkage to biotic and abiotic variables in benthic estuarine ecosystem. This contemporaneous community will be the backdrop for understanding the response of autochthonous community to increasing anthropogenic stress.
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Motivation for the present study is to improve the scienti c understanding on the prominent gap areas in the average three-dimensional distribution of clouds and their impact on the energetics of the earth-atmosphere system. This study is focused on the Indian subcontinent and the surrounding oceans bound within the latitude-longitude bands of 30 S to 30 N and 30 E to 110 E. Main objectives of this study are to : (i) estimate the monthly and seasonal mean vertical distributions of clouds and their spatial variations (which provide the monthly and seasonal mean 3-dimensional distributions of clouds) using multi-year satellite data and investigate their association with the general circulation of the atmosphere, (ii) investigate the characteristics of the `pool of inhibited cloudiness' that appear over the southwest Bay of Bengal during the Asian summer monsoon season (revealed by the 3-dimensional distribution of clouds) and identify the potential mechanisms for its genesis, (iii) investigate the role of SST and atmospheric thermo-dynamical parameters in regulating the vertical development and distribution of clouds, (iv) investigate the vertical distribution of tropical cirrus clouds and their descending nature using lidar observations at Thiruvananthapuram (8.5 N, 77 E), a tropical coastal station at the southwest Peninsular India, and (v) assessment of the impact of clouds on the energetics of the earth-atmosphere system, by estimating the regional seasonal mean cloud radiative forcing at top-of-the-atmosphere (TOA) and latent heating of the atmosphere by precipitating clouds using satellite data
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Evolution of mini warm pool in the Arabian Sea just before the onset of southwest monsoon and behavior of SST in the vicinity of weather systems formed during the premonsoon, southwest monsoon and post monsoon seasons were studied using TMI SST data. The Arabian Sea mini warm pool is formed about three weeks ahead of onset of southwest monsoon. Maximum SST is found about one week ahead of monsoon onset and then the warm pool gradually dissipated. Generally, a low-pressure system is formed when the SST exceeds a certain threshold value for the formation of the system. Daily SST values are examined both in Arabian sea and Bay of Bengal to bring out the quantity of increase in SST just before the formation of the system, quantity of rapid decrease in SST during the formation of the system and the number of days required for returning to normal SST. Many cases were examined for pre-monsoon, southwest monsoon and post monsoon seasons to understand the behavior of SST pattern. It is found that the SST increases about 3° C just before the formation of the system and decreases about 4° C during the formation within 2 to 3 days and takes about 4 to 6 days to return to normal SST pattern. However, the SST pattern depends on the weather system
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According to current knowledge, convection over the tropical oceans increases with sea surface temperature (SST) from 26 to 29 °C, and at SSTs above 29 °C, it sharply decreases. Our research shows that it is only over the summer warm pool areas of Indian and west Pacific Oceans (monsoon areas) where the zone of maximum SST is away from the equator that this kind of SST-convection relationship exists. In these areas (1) convection is related to the SST gradient that generates low-level moisture convergence and upward vertical motion in the atmosphere. This has modelling support. Regions of SST maxima have low SST gradients and therefore feeble convection. (2) Convection initiated by SST gradient produces strong wind fields particularly cross-equatorial low-level jetstreams (LLJs) on the equator-ward side of the warm pool and both the convection and LLJ grow through a positive feedback process. Thus, large values of convection are associated with the cyclonic vorticity of the LLJ in the atmospheric boundary layer. In the inter-tropical convergence zone (ITCZ) over the east Pacific Ocean and the south Pacific convergence zone (SPCZ) over the west Pacific Ocean, low-level winds from north and south hemisphere converge in the zone of maximum SST, which lies close to the equator producing there elongated bands of deep convection, where we find that convection increases with SST for the full range of SSTs unlike in the warm pool regions. The low-level wind divergence computed using QuikSCAT winds has large and significant linear correlation with convection in both the warm pool and ITCZ/SPCZ areas. But the linear correlation between SST and convection is large only for the ITCZ/SPCZ. These findings have important implications for the modelling of largescale atmospheric circulations and the associated convective rainfall over the tropical oceans
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Heterotrophic bacterial flora of Pmonadon from an apparently healthy hatchery system as well as a pool with heavy mortality were isolated and studied. In the healthy systems comparatively higher generic diversity with Pseudomonas, Acinetobacter, Bacillus, Micrococcus, members of the family Enterobacteriaceae and coryneform group in the diminishing order of dominance was recorded. Meanwhile from the moribund larvae and rearing water Aeromonas and Pseudomonas could be isolated in almost equal proportions. Strikingly, Aeromonas could not be isolated from the apparently healthy larval rearing system and its exclusive occurrence in the sick culture system in comparatively higher percentage suggested its possible role in the mortality. They were found to be highly halophilic exhibiting growth at 10% NaCl. On testing their sensitivity to twenty antibiotics, four of them (Streptomycin, Gentamycin, Methamine mandelate and Cloramphenicol) were found to be effective on all the isolates of Aeromonas and Pseudomonas suggesting their possible application in the hatchery system in times of emergency. While doing so, Streptomycin would do comparatively better than the others as the minimum inhibitory dose required was comparatively lower (200ppm) within a period of 24 hours
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The presence of microcalcifications in mammograms can be considered as an early indication of breast cancer. A fastfractal block coding method to model the mammograms fordetecting the presence of microcalcifications is presented in this paper. The conventional fractal image coding method takes enormous amount of time during the fractal block encoding.procedure. In the proposed method, the image is divided intoshade and non shade blocks based on the dynamic range, andonly non shade blocks are encoded using the fractal encodingtechnique. Since the number of image blocks is considerablyreduced in the matching domain search pool, a saving of97.996% of the encoding time is obtained as compared to theconventional fractal coding method, for modeling mammograms.The above developed mammograms are used for detectingmicrocalcifications and a diagnostic efficiency of 85.7% isobtained for the 28 mammograms used.
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In this paper, a novel fast method for modeling mammograms by deterministic fractal coding approach to detect the presence of microcalcifications, which are early signs of breast cancer, is presented. The modeled mammogram obtained using fractal encoding method is visually similar to the original image containing microcalcifications, and therefore, when it is taken out from the original mammogram, the presence of microcalcifications can be enhanced. The limitation of fractal image modeling is the tremendous time required for encoding. In the present work, instead of searching for a matching domain in the entire domain pool of the image, three methods based on mean and variance, dynamic range of the image blocks, and mass center features are used. This reduced the encoding time by a factor of 3, 89, and 13, respectively, in the three methods with respect to the conventional fractal image coding method with quad tree partitioning. The mammograms obtained from The Mammographic Image Analysis Society database (ground truth available) gave a total detection score of 87.6%, 87.6%, 90.5%, and 87.6%, for the conventional and the proposed three methods, respectively.
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Phosphorus fractionation was employed to find the bioavailability of phosphorus and its seasonal variations in the Panangad region of Cochin estuary, the largest estuarine system in the southwest coast of India. Sequential extraction of the surficial sediments using chelating agents was taken as a tool for this. Phosphate in the water column showed seasonal variations, with high values during the monsoon months, suggesting external runoff. Sediment texture was found to be the main factor influencing the spatial distribution of the geochemical parameters in the study region. Similarly, total phosphorus also showed granulometric dependence and it ranged between 319.54 and 2,938.83 μg/g. Calcium-bound fraction was the main phosphorus pool in the estuary. Significant spatial variations were observed for all bioavailable fractions; iron-bound inorganic phosphorus (5.04–474.24 μg/g), calcium-bound inorganic phosphorus (11.16–826.09 μg/g), and acidsoluble organic phosphorus (22.22–365.86 μg/g). Among the non-bioavailable phosphorus, alkalisoluble organic fraction was the major one (51.92– 1,002.45 μg/g). Residual organic phosphorus was K. R. Renjith (B) · N. Chandramohanakumar · M. M. Joseph Department of Chemical Oceanography, School of Marine Sciences, Cochin University of Science and Technology, Kochi 682016, Kerala, India e-mail: renjithaqua@gmail.com comparatively smaller fraction (3.25–14.64% of total). The sandy and muddy stations showed distinct fractional composition and the speciation study could endorse the overall geochemical character. There could be buffering of phosphorus, suggested by the increase in the percentage of bioavailable fractions during the lean premonsoon period, counteracting the decreases in the external loads. Principal component analysis was employed to find the possible processes influencing the speciation of phosphorus in the study region
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In der vorliegenden Arbeit werden die Auswirkungen von Umweltveränderungen in einem N-gesättigten Buchenwaldökosystem über Basalt (Braunerde) untersucht. Unter veränderten Umweltbedingungen sind hier vor allem Bestandesdachauflösung, immissions- oder waldbaulich bedingt, und Klimaveränderung zu verstehen, die eine Erwärmung des Oberbodens zur Folge haben. Die Änderungen der Umweltbedingungen werden in diesem Versuchsansatz durch einen waldbaulichen Eingriff simuliert, durch den eine Bestandeslücke entsteht, die in einer Erwärmung des Bodens resultieren und damit den Wasser- und Elementhaushalt insgesamt beeinflussen. Es wird deutlich, dass die in der vorliegenden Arbeit untersuchten Flächen als N-gesättigt bezeichnet werden können, da die N-Verluste aus dem System die Größe der Einträge überschreiten. In der Folge ist es zu einer Entkopplung des Stoffhaushalts und damit zu erhöhter N-Mobilisierung gekommen. Diese konnte vor allem im hydrologischen Jahr 1996 dokumentiert werden; der Überschuss-N-Output liegt auf der Auflichtungsfläche bei bis zu 50 kg N/(ha*a)! Die beobachteten hohen N-Austräge erfolgten trotz eines ebenfalls beobachteten Anwachsens des mikrobiellen Stickstoff-Pools und des Aufwachsens einer krautigen und strauchigen Vegetation auf der Auflichtungsfläche. Im Jahresgang konnten auf der Auflichtungsfläche in 0 - 30 cm Bodentiefe maximale Änderungen im Nmic-Vorrat von 130 kg N/(ha*a) beobachtet werden. Das im Frühjahr beginnende quantitative Anwachsen des mikrobiellen Stickstoff-Pools mit dem Jahresgang zeigt vor allem dessen Temperaturabhängigkeit auf. Die am Ende der Vegetationsperiode deutlich ansteigenden Austragsraten zeigen jedoch an, dass der freigesetzte Stickstoff auch von den Mikroorganismen nicht dauerhaft im System gehalten werden kann, da mit fallender Temperatur auch die Mikroorganismen absterben und der in ihrer Biomasse gespeicherte Stickstoff freigesetzt wird. Aufwachsende Vegetation auf der Auflichtungsfläche konnte einen Großteil des Netto-Stickstoff-Jahreseintrages aufnehmen. Da die "Netto-Jahres-Mineralisation" 1996 leicht über der Wurzelaufnahme liegt, verbleibt ein Rest, der nicht von der aufwachsenden krautigen Vegetation der Auflichtungsfläche aufgenommen werden kann. Ergebnis ist damit, dass die auf Lochhieben aufwachsende krautige und strauchige Vegetation eine temperaturbedingte Stickstoffmobilisierung nur teilweise kompensieren kann. Allein aufwachsende verholzende Vegetation kann Stickstoff langfristig im System binden.
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Im Informationszeitalter erhalten die Neuen Medien eine immer größer werdende Bedeutung. Lange Zeit galten gedruckte Informationen – häufig in Form von Büchern und Zeitschriften – als eigentliche Informationsquelle in den Bibliotheken. Mehr und mehr nehmen jedoch mittlerweile auch multimediale Anwendungen breiteren Raum ein, gilt es doch, sich den veränderten Lese- und insbesondere Informationsgewohnheiten anzupassen. Insbesondere sollen elektronische Informationsquellen und digitale Literatur erschlossen und bereitgestellt werden. Im Zuge dieser Entwicklung wurde durch die hessische Ministerin für Wissenschaft und Kunst am 11.11.1998 in der Gesamthochschulbibliothek Kassel eine neugeschaffene Multi-Media-Thek (MMT) eröffnet. In dieser Multimediathek sollen die Bibliotheksbenutzer die Möglichkeit erhalten, die Neuen Medien zu erkunden und gewinnbringend für ihre Fragestellungen einzusetzen. Neben den mittlerweile weiter verbreiteten Internetarbeitsplätzen haben die Benutzer Gelegenheit, an speziell ausgestatteten Arbeitsplätzen Audio- und Videoanwendungen zu testen. Die zur Verfügung stehenden Arbeitsplätze sind plattformübergreifend gestaltet, neben Windows NT-Rechnern können Macintosh-, Java- und Linux-Rechner benutzt werden. Alle PC-Systeme verfügen über hochauflösende Grafik- und Soundkarten, allerdings müssen zum Abhören von Audio-Medien, DVD’s oder Multimedia-CD’s entsprechende Kopfhörer aufgesetzt werden. Über WinCenter können auch auf Linux- und Macintosh-Rechnern CD-Applikationen aus dem GHB-internen CD-Server angewählt werden. Zur Auswahl stehen derzeit 140 Datenbanken, die zudem ergänzt werden durch entsprechende Datenbankzugriffe auf den Silverplatter-Server der GHB. In separaten Klein-Arbeitsräumen können Audio-Cassetten und Video-Bänder benutzt werden. Natürlich lassen sich auch herkömmliche Dias und Microfiches in den Räumen der MMT betrachten und Ausdrucke über den Reader-Printer bzw. über das Bibliotheksnetz auf einen zentralen Benutzer-Drucker (OCE-Drucksystem mit Entgeldregelung) machen. Als Auslegestelle für DIN-Normen kann im DIN-Katalog über Internet recherchiert und das Ergebnis der Recherche direkt im DIN-Bestand angesehen werden. In einem speziell eingerichteten Macintosh-Pool sind mittels Scanner, Grafikbearbeitungssoftware und OCR-Möglichkeit weitere Bedingungen für multimediales Arbeiten geschaffen. Sie sollen bei entsprechendem Bedarf um digitale Bildbearbeitung (Photo, Video) gegebenenfalls ergänzt werden. Die Bibliothek bietet in den Räumen der Multimediathek entsprechende Schulungen zur effektiven Nutzung der Rechnerausstattung an.