Die musikalischen Reisen des Herrn von Uffenbach : aus einem Reisetagebuch des Johann Friedrich A. von Uffenbach aus Frankfurt a.M. 1712 - 1716

Eberhard Preußner

Johann Peter Groetzner im Ruhestand

Biographie und Danksagung an Johann Peter Groetzner

Johann Gottfried von Herder's Erläuterungen zum Neuen Testament aus einer neueröfneten morgenländischen quelle. 1775 ...

"Briefe zweener brüder Jesu in unserem kanon": p. [183]-211.

El mejor tobogán... o el ingenio matemático de Johann Bernoulli

En la sección de cabeza del número anterior de SUMA habíamos dejado a Galileo sumido en su sutil pero lamentable error de que la curva por la que una bola caería de un punto más alto a otro más bajo en el menor tiempo posible sería un arco de circunferencia que uniese ambos puntos. Johann, el pequeño de los Bernoulli, ya sabía que Galileo estaba equivocado cuando lanzó en el verano de 1696, el reto público, pensando más en provocar a su hermano mayor Jacob que en otra cosa, de encontrar la auténtica curva braquistócrona, la de tiempo más breve posible.

Old archetype rides into Bell's hell [Review]

BILLED as a trip to hell, Bell Shakespeare and Queensland Theatre Company's production of Faustus is adapted from Christopher Marlowe's Doctor Faustus and Johann Wolfgang von Goethe's fragmentary Urfaust, an early version of Goethe's enormous two-volume Faust tragedy published in 1808, then in full in 1832

Effect of consecutive repeated sprint and resistance exercise bouts on acute adaptive responses in human skeletal muscle

We examined acute molecular responses in skeletal muscle to repeated sprint and resistance exercise bouts. Six men [age, 24.7 ± 6.3 yr; body mass, 81.6 ± 7.3 kg; peak oxygen uptake, 47 ± 9.9 ml·kg -1 ·min -1; one repetition maximum (1-RM) leg extension 92.2 ± 12.5 kg; means ± SD] were randomly assigned to trials consisting of either resistance exercise (8 × 5 leg extension, 80% 1-RM) followed by repeated sprints (10 × 6 s, 0.75 N·m torque·kg -1) or vice-versa. Muscle biopsies from vastus lateralis were obtained at rest, 15 min after each exercise bout, and following 3-h recovery to determine early signaling and mRNA responses. There was divergent exercise order-dependent phosphorylation of p70 S6K (S6K). Specifically, initial resistance exercise increased S6K phosphorylation (?75% P < 0.05), but there was no effect when resistance exercise was undertaken after sprints. Exercise decreased IGF-I mRNA following 3-h recovery (?50%, P = 0.06) independent of order, while muscle RING finger mRNA was elevated with a moderate exercise order effect (P < 0.01). When resistance exercise was followed by repeated sprints PGC-1? mRNA was increased (REX1-SPR2; P = 0.02) with a modest distinction between exercise orders. Repeated sprints may promote acute interference on resistance exercise responses by attenuating translation initiation signaling and exacerbating ubiquitin ligase expression. Indeed, repeated sprints appear to generate the overriding acute exercise-induced response when undertaking concurrent repeated sprint and resistance exercise. Accordingly, we suggest that sprint-activities are isolated from resistance training and that adequate recovery time is considered within periodized training plans that incorporate these divergent exercise modes.

Phosphoprotein pathway mapping: Akt/Mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

Mapping of protein signaling networks within tumors can identify new targets for therapy and provide a means to stratify patients for individualized therapy. Despite advances in combination chemotherapy, the overall survival for childhood rhabdomyosarcoma remains ∼60%. A critical goal is to identify functionally important protein signaling defects associated with treatment failure for the 40% nonresponder cohort. Here, we show, by phosphoproteomic network analysis of microdissected tumor cells, that interlinked components of the Akt/mammalian target of rapamycin (mTOR) pathway exhibited increased levels of phosphorylation for tumors of patients with short-term survival. Specimens (n = 59) were obtained from the Children's Oncology Group Intergroup Rhabdomyosarcoma Study (IRS) IV, D9502 and D9803, with 12-year follow-up. High phosphorylation levels were associated with poor overall and poor disease-free survival: Akt Ser473 (overall survival P < 0.001, recurrence-free survival P < 0.0009), 4EBP1 Thr37/46 (overall survival P < 0.0110, recurrence-free survival P < 0.0106), eIF4G Ser1108 (overall survival P < 0.0017, recurrence-free survival P < 0.0072), and p70S6 Thr389 (overall survival P < 0.0085, recurrence-free survival P < 0.0296). Moreover, the findings support an altered interrelationship between the insulin receptor substrate (IRS-1) and Akt/mTOR pathway proteins (P < 0.0027) for tumors from patients with poor survival. The functional significance of this pathway was tested using CCI-779 in a mouse xenograft model. CCI-779 suppressed phosphorylation of mTOR downstream proteins and greatly reduced the growth of two different rhabdomyosarcoma (RD embryonal P = 0.00008; Rh30 alveolar P = 0.0002) cell lines compared with controls. These results suggest that phosphoprotein mapping of the Akt/mTOR pathway should be studied further as a means to select patients to receive mTOR/IRS pathway inhibitors before administration of chemotherapy.

Cuantificación del carbono almacenado en suelo de café (Coffea arábica L.) con sombra en la comarca Palo de Sombrero, Jinotega, Nicaragua

Las emanaciones de gases provocan el efecto de invernadero el cual consiste en el calentamiento de la atmósfera y superficie de la tierra. Los sistemas agroforestales son potenciales sumideros de dióxido de carbono (C02) que pueden contribuir a mitigar el efecto de las emisiones globales principalmente del C0 2 . El propósito de este trabajo es cuantificar el carbono (C) almacenado en el suelo del sistema agroforestal de café( Coffea arábica L. ). Este estudio se desarrolló en la Hacienda Santa Maura, Jinotega, altitud 1000–1250 msnm, temperatura promedio de 19 a 23º C. Los suelos son: Vertic aquic Argidolls, Thypic entic Hapludoll y Thypic cumulic Argiudolls. Se identificaron tres tipologías de cafeto que se diferencian por su variedad, edad y densidad de establecimiento. Se realizó un muestreo sistemático, Intensidad 2 %, la unidad de muestreo es la parcela circular de 250 m 2 . Se tomaron muestra de hojarasca con un marco metálico de 0.25 m 2 para determinar carbono orgánico, así mismo, se colectaron muestras de suelo a tres profundidades: 0-10, 10-20, 20–30 cm. El C encontrado en tejido de hojarasca se determinó por el método de Schollemberger y la del suelo por Walkley-BlacK. El almacenamiento de C muestra significancía entre tipologías ( P <0.01). Al realizar separaciones de media por Tukey, se encontró que la tipología tres reportó el mayor promedio de C almacenado con 98.22 C ton/ha, siguiéndole, el tipo dos con 78.66 C ton/ha y por último, el tipo uno con 76.96 C ton/ha.Las últimas dos tipologías no muestran diferencia estadística en el almacenaje de carbono. El almacenamiento de C en el suelo por las tipologías de cafeto fue en promedio de 84.28 C ton/ha de las cuales, la mayor cantidad se encontró en el suelo mineral: 83 C ton/ha (98.48 %), siguiéndole en orden la hojarasca con 1.28 25 C ton/ha (1.52 %). La diferencia de contenido de C en el suelo entre tipología, está directamente ligado en el cambio de uso del suelo, densidad, especie de árbol de sombra, edad y manejo de la plantación.

Reise im innern von brasilien : auf allerhochsten befehl selner majestat des kaisers von osterreich, Franz des Esten, in den jahren 1817-1821 unternonmen und herausgegeben

O primeiro volume foi editado em 1832 e o segundo em 1837, após a morte do autor, fato que contribuiu para a pouco acurada nomenclatura em português verificada no segundo volume, conforme afirma Borba de Moraes. A grande importância do trabalho de Pohl residiu na descrição de Goiás, à época, uma parte do Brasil quase desconhecida para os cientistas estrangeiros. Seu texto contém descrições sobre a arquitetura colonial e do século XIX. Pohl também produziu um atlas que complementou, por meio de belas ilustrações, o trabalho contido nesses dois volumes. Estes, especialmente se acompanhados do atlas, são um trabalho mais raro do que os relativos às viagens de Martins

AUSTRO-GERMAN VIOLIN REPERTORIE FROM BAROQUE THROUGH ROMANTIC PERIOD

At the end of the sixteenth century, Germany had become one of the most active centers of early Baroque music, and therefore Austro-German music came to dominate Western music. An investigation of violin works written during this period reveals the ways in which Austro-German compositions are extraordinary contributions to the violin repertoire. This research warranted further study and performance of these works in order to determine what influence these composers had on the violin repertoire as a whole. For my dissertation recital project, I trace the history of works for violin focusing the violin concerto repertoire in particular. A genre which remained popular throughout the century, the nineteenth-century concerto served primarily as a vehicle for virtuosic display of the violin and piano as never before. For my research I studied and performed works selected from the Baroque through the Romantic period in three recorded recitals with collaborative pianists Ilya Sinaisky, Sun-ha Yun, and Seyon Lee at the Gildenhorn Recital Hall, Clarice Smith Performing Arts Center. I selected particularly prominent pieces which represent the work of significant composers from each period. The composers discussed include Johann Sebastian Bach (1685-1750), owing to the fact that his works are the culmination of the Baroque era during the first half of the eighteenth century; from the Classical period, Wolfgang Amadeus Mozart (1756-1791) all of whom emerged mixing German and Italian traditions into his own style, and Ludwig van Beethoven (1770-1827), the bridge composer between the Classical and the Romantic periods; Romantic composers, Franz Schubert (1979-1828), Johannes Brahms (1833-1897), Robert Schumann (1810-1856), Felix Mendelssohn (1809-1847), and Max Bruch (1838-1920), all who tended to mix Classic and Romantic elements. As a violinist, I learned that their own original sound, rich harmonies and unique expression made these works worthy of becoming masterpieces. I have relished the opportunity for musical and professional growth in exploring these substantial compositions.

VARIATION FORMS: A SURVEY THROUGH FOUR CENTURIES OF VIOLIN REPERTOIRE

Variation, or the re-working of existing musical material, has consistently attracted the attention of composers and performers throughout the history of Western music. In three recorded recitals at the University of Maryland School of Music, this dissertation project explores a diverse range of expressive possibilities for violin in seven types of variation form in Austro-German works for violin from the 17th through the 20th centuries. The first program, consisting of Baroque Period works, performed on period instrument, includes the divisions on “John come kiss me now” from The Division Violin by Thomas Baltzar (1631 – 1663), constant bass variations in Sonate Unarum Fidium by Johann Heinrich von Schmelzer (1623 – 1680), arbitrary variation in Sonata for Violin and Continuo in E Major, Op. 1, No. 12 “Roger” by George Friedrich Händel (1685 – 1759), and French Double style, melodic-outline variation in Partita for Unaccompanied Violin in B Minor by Johan Sebastian Bach (1685 – 1750). Theme and Variations, a popular Classical Period format, is represented by the Sonata for Piano and Violin in G Major K. 379 by Wolfgang Amadeus Mozart (1756 – 1791) and Sonata for Violin and Piano in A Major, Op. 47 No. 9 the “Kreutzer” by Ludwig van Beethoven (1770 – 1827). Fantasy for Piano and Violin in C Major D. 934 by Franz Schubert (1797 – 1828) represents the 19th century fantasia variation. In these pieces, the piano and violin parts are densely interwoven, having equal importance. Many 20th century composers incorporated diverse types of variations in their works and are represented in the third recital program comprising: serial variation in the Phantasy for Violin and Piano Op.47 of Arnold Schoenberg (1874 – 1951); a strict form of melodic-outline variation in Sonate für Violine allein, Op. 31, No. 2 of Paul Hindemith (1895 – 1963); ostinato variation in Johan Halvorsen’s (1864 – 1935) Passacaglia for Violin and Viola, after G. F. Handel’s Passacaglia from the Harpsichord Suite No. 7 in G Minor. Pianist Audrey Andrist, harpsichordist Sooyoung Jung, and violist Dong-Wook Kim assisted in these performances.

Mendelssohn and The Schübler Chorales (BWV 645-650):A New Source found in the Riemenschneider Bach Institute Collection

This article discusses a hitherto-unknown printed edition of Bach's Schübler Chorales edited by Mendelssohn, and considers its meaning and significance for Bach-Mendelssohn scholarship. Facsimile of the edition is also included.