953 resultados para Labor unions and communism


Relevância:

100.00% 100.00%

Publicador:

Resumo:

There is a rich history of social science research centering on racial inequalities that continue to be observed across various markets (e.g., labor, housing, and credit markets) and social milieus. Existing research on racial discrimination in consumer markets, however, is relatively scarce and that which has been done has disproportionately focused on consumers as the victims of race-based mistreatment. As such, we know relatively little about how consumers contribute to inequalities in their roles as perpetrators of racial discrimination. In response, in this paper we elaborate on a line of research that is only in its’ infancy stages of development and yet is ripe with opportunities to advance the literature on consumer racial discrimination and racial earnings inequities among tip dependent employees in the United States. Specifically, we analyze data derived from a large exit survey of restaurant consumers (n=378) in an attempt to replicate, extend, and further explore the recently documented effect of service providers’ race on restaurant consumers’ tipping decisions. Our results indicate that both White and Black restaurant customers discriminate against Black servers by tipping them less than their White coworkers. Importantly, we find no evidence that this Black tip penalty is the result of interracial differences in service skills possessed by Black and White servers. We conclude by delineating directions for future research in this neglected but salient area study.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

In spite of impressive rates of economic growth, the quality of the labor force’s human capital is considered a major challenge for sustaining medium term economic growth in Peru. This note reviews the skills of the Peruvian labor force, and the status of the continuous education and training system. Based on such an assessment and on learnings from international best practices, it proposes a system of continuous education and training that draws from international best practices, but that addresses local capacity and institutional issues.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Cancer and cardio-vascular diseases are the leading causes of death world-wide. Caused by systemic genetic and molecular disruptions in cells, these disorders are the manifestation of profound disturbance of normal cellular homeostasis. People suffering or at high risk for these disorders need early diagnosis and personalized therapeutic intervention. Successful implementation of such clinical measures can significantly improve global health. However, development of effective therapies is hindered by the challenges in identifying genetic and molecular determinants of the onset of diseases; and in cases where therapies already exist, the main challenge is to identify molecular determinants that drive resistance to the therapies. Due to the progress in sequencing technologies, the access to a large genome-wide biological data is now extended far beyond few experimental labs to the global research community. The unprecedented availability of the data has revolutionized the capabilities of computational researchers, enabling them to collaboratively address the long standing problems from many different perspectives. Likewise, this thesis tackles the two main public health related challenges using data driven approaches. Numerous association studies have been proposed to identify genomic variants that determine disease. However, their clinical utility remains limited due to their inability to distinguish causal variants from associated variants. In the presented thesis, we first propose a simple scheme that improves association studies in supervised fashion and has shown its applicability in identifying genomic regulatory variants associated with hypertension. Next, we propose a coupled Bayesian regression approach -- eQTeL, which leverages epigenetic data to estimate regulatory and gene interaction potential, and identifies combinations of regulatory genomic variants that explain the gene expression variance. On human heart data, eQTeL not only explains a significantly greater proportion of expression variance in samples, but also predicts gene expression more accurately than other methods. We demonstrate that eQTeL accurately detects causal regulatory SNPs by simulation, particularly those with small effect sizes. Using various functional data, we show that SNPs detected by eQTeL are enriched for allele-specific protein binding and histone modifications, which potentially disrupt binding of core cardiac transcription factors and are spatially proximal to their target. eQTeL SNPs capture a substantial proportion of genetic determinants of expression variance and we estimate that 58% of these SNPs are putatively causal. The challenge of identifying molecular determinants of cancer resistance so far could only be dealt with labor intensive and costly experimental studies, and in case of experimental drugs such studies are infeasible. Here we take a fundamentally different data driven approach to understand the evolving landscape of emerging resistance. We introduce a novel class of genetic interactions termed synthetic rescues (SR) in cancer, which denotes a functional interaction between two genes where a change in the activity of one vulnerable gene (which may be a target of a cancer drug) is lethal, but subsequently altered activity of its partner rescuer gene restores cell viability. Next we describe a comprehensive computational framework --termed INCISOR-- for identifying SR underlying cancer resistance. Applying INCISOR to mine The Cancer Genome Atlas (TCGA), a large collection of cancer patient data, we identified the first pan-cancer SR networks, composed of interactions common to many cancer types. We experimentally test and validate a subset of these interactions involving the master regulator gene mTOR. We find that rescuer genes become increasingly activated as breast cancer progresses, testifying to pervasive ongoing rescue processes. We show that SRs can be utilized to successfully predict patients' survival and response to the majority of current cancer drugs, and importantly, for predicting the emergence of drug resistance from the initial tumor biopsy. Our analysis suggests a potential new strategy for enhancing the effectiveness of existing cancer therapies by targeting their rescuer genes to counteract resistance. The thesis provides statistical frameworks that can harness ever increasing high throughput genomic data to address challenges in determining the molecular underpinnings of hypertension, cardiovascular disease and cancer resistance. We discover novel molecular mechanistic insights that will advance the progress in early disease prevention and personalized therapeutics. Our analyses sheds light on the fundamental biological understanding of gene regulation and interaction, and opens up exciting avenues of translational applications in risk prediction and therapeutics.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Includes indexes.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Includes indexes.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Music making was a common practice during the 1989−90 strike against the Pittston Coal Company, an action led by the United Mine Workers of America. The types of music made varied greatly based on the contexts in which musicians and protesters were participating. In this thesis, I discuss how performers and audiences engaged with the music of the Pittston strike, with a focus on how different participatory and presentational contexts included music with similar or the same lyrics to achieve different goals. I argue that the musicians’ understanding of the people around them as potential participants, audiences, or inherent audiences shifted their use of music as they worked to use music strategically and effectively for the strike. The musical methods and considerations of the Pittston strike protesters have had a lasting impact on more recent protest movements.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Cette recherche fait état de la crise du syndicalisme qui affecte la capacité d’action et l’efficacité des pratiques des organisations syndicales à travers le monde. Elle dresse un portrait complet des éléments de crise qu’elle décline sous les niveaux économique, politique et social. Cette recherche expose ainsi la nécessité d’un renouveau syndical pour porter précisément sur les coalitions, hétérogènes notamment, comme stratégie de renouveau syndical. Au plan analytique, elle évalue l’impact de l’identité et de la capacité organisationnelle d’une organisation syndicale aux Philippines sur son choix de se coaliser, mais aussi l’influence de ses objectifs et du contexte national dans lequel elle évolue. Les données empiriques pour mener cette étude proviennent principalement de près de 24 entrevues semi-dirigées, tenues auprès de représentants de l’une des plus grandes organisations syndicales des Philippines, de représentants d’organisations non syndicales alliées et de répondants externes à celle-ci. Premièrement, nos résultats montrent qu’une identité collective sociétale forte influence favorablement le choix de l’organisation syndicale étudiée de se coaliser. Elle confirme également le rôle essentiel de l’identité dans l’orientation de son action collective. Deuxièmement, nos résultats permettent de conclure qu’une capacité organisationnelle forte influence favorablement le choix de cette organisation syndicale de se coaliser, considérant qu’elle permet à celle-ci d’identifier les opportunités d’action, de mettre en œuvre de nouvelles stratégies et d’assurer la légitimité et la mobilisation des membres quant aux actions entreprises. De nos résultats ressort l’importance de l’éducation sur l’accroissement de la capacité organisationnelle et, particulièrement, sur la formation et le renforcement de l’identité collective de l’organisation syndicale étudiée. Plus encore, nos résultats exposent l’interaction entre les dimensions de l’identité et de la capacité organisationnelle : précisément, nous avons observé une relation de renforcement positif entre ces deux variables. Troisièmement, nos résultats mettent de l’avant l’interaction entre les différents niveaux de transformations résultantes de sa participation à différents types de coalitions. Ainsi dans le cas observé, l’obtention de transformation au plan intraorganisationnel permet à rebours d’obtenir des transformations au plan extraorganisationnel et vice-versa. Finalement, le contexte répressif des Philippines et les objectifs de l’organisation syndicale étudiée apparaissent favorables à son choix de se coaliser à différents niveaux (local, régional, national et international).

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Includes bibliographical references.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Description based on: 39th (1915)

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Forty years ago began in Medellin, Colombia the officers of study on the training of librarians and the improvement of library service in Latin America. It was the first time was a regional effort of this nature.Reviewing the documents we see that concern for the subsequent employment of graduates are handled in a "serene". The library moved into a more stable labor market and institutionally defined. The challenges facing those who were far from threatening the stability of employment, the very meaning of the profession and survival. The race was expanding, had begun to trickle out of the national libraries of some countries to join full of expectations to the academic university.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Published: 11th- 1877- in its Cigar makers official journal.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Includes the proceedings of the Miscellaneous Division and the Skilled Division, previously held and published separately.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

No more published?

Relevância:

100.00% 100.00%

Publicador:

Resumo:

"Prepared by G. Joachim [i.e. Joachim G.] Elterich and Linda Graham"--Prelim. p.