969 resultados para LINGUISTICA ITALIANA,00789,Scienze della Formazione,0013,Scienze della formazione primaria,1313,ESAME INTEGRATO DI LINGUISTICA ITALIANA - DIDATTICA DELLA LINGUA ITALIANA (II MODULO),22123,SCUOLA ELEMENTARE,253,MAIOR LINGUA STRANIERA,229,2007,3
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A reliable and robust routing service for Flying Ad-Hoc Networks (FANETs) must be able to adapt to topology changes, and also to recover the quality level of the delivered multiple video flows under dynamic network topologies. The user experience on watching live videos must also be satisfactory even in scenarios with network congestion, buffer overflow, and packet loss ratio, as experienced in many FANET multimedia applications. In this paper, we perform a comparative simulation study to assess the robustness, reliability, and quality level of videos transmitted via well-known beaconless opportunistic routing protocols. Simulation results shows that our developed protocol XLinGO achieves multimedia dissemination with Quality of Experience (QoE) support and robustness in a multi-hop, multi-flow, and mobile networks, as required in many multimedia FANET scenarios.
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David Glauser untersucht die Frage nach den Ursachen von Ungleichheiten nach sozialer Herkunft, Geschlecht und Migrationshintergrund in der Bildungsentscheidung beim Übergang von der obligatorischen Schule in berufsspezifische und allgemeinbildende Ausbildungen der Sekundarstufe II in der Schweiz. Der Ergebnisteil beinhaltet einerseits eine Deskription des Entscheidungsverlaufs von Jugendlichen der Schulaustrittskohorte des Jahres 2013. Andererseits werden zentrale Argumente der Wert-Erwartungstheorien und damit der Einfluss von Herkunftseffekten zur Erklärung sozial ungleicher Bildungsentscheidungen empirisch überprüft.
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BACKGROUND The growth potential of the tumor-like Echinococcus multilocularis metacestode (causing alveolar echinococcosis, AE) is directly linked to the nature/function of the periparasitic host immune-mediated processes. We previously showed that Fibrinogen-like-protein 2 (FGL2), a novel CD4+CD25+ Treg effector molecule, was over-expressed in the liver of mice experimentally infected with E. multilocularis. However, little is known about its contribution to the control of this chronic helminth infection. METHODS/FINDINGS Key parameters for infection outcome in E. multilocularis-infected fgl2-/- (AE-fgl2-/-) and wild type (AE-WT) mice at 1 and 4 month(s) post-infection were (i) parasite load (i. e. wet weight of parasitic metacestode tissue), and (ii) parasite cell proliferation as assessed by determining E. multilocularis 14-3-3 gene expression levels. Serum FGL2 levels were measured by ELISA. Spleen cells cultured with ConA for 48h or with E. multilocularis Vesicle Fluid (VF) for 96h were analyzed ex-vivo and in-vitro. In addition, spleen cells from non-infected WT mice were cultured with rFGL2/anti-FGL2 or rIL-17A/anti-IL-17A for further functional studies. For Treg-immune-suppression-assays, purified CD4+CD25+ Treg suspensions were incubated with CD4+ effector T cells in the presence of ConA and irradiated spleen cells as APCs. Flow cytometry and qRT-PCR were used to assess Treg, Th17-, Th1-, Th2-type immune responses and maturation of dendritic cells. We showed that AE-fgl2-/- mice exhibited (as compared to AE-WT-animals) (a) a significantly lower parasite load with reduced proliferation activity, (b) an increased T cell proliferative response to ConA, (c) reduced Treg numbers and function, and (d) a persistent capacity of Th1 polarization and DC maturation. CONCLUSIONS FGL2 appears as one of the key players in immune regulatory processes favoring metacestode survival by promoting Treg cell activity and IL-17A production that contributes to FGL2-regulation. Prospectively, targeting FGL2 could be an option to develop an immunotherapy against AE and other chronic parasitic diseases.
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This study assesses adolescent's health issues in Comal County, TX. Adolescents are defined as youth between the ages of 12 to 17 years of age, who resided in Comal County during the time period of 2000 to 2007. The analysis focused on high risk behaviors including use of gateway drugs—tobacco and alcohol; illegal substance use; and reproductive health related indicators, including sexual activity, sexually transmitted diseases, and pregnancy. This study is based on the primary and secondary data collected as part of the 2008 Comal County Community Assessment. It compares findings from the primary data sources to extant data from four secondary data sources including: (1) The Centers for Disease Control & Prevention (national) Healthy People 2010; (2) The Centers for Disease Control & Prevention, Youth Risk Behavior Surveillance Survey, 2007; (3) The Texas Department of State Health Services, 2000 to 2007; and The Pride Survey (Local and Statewide). The methods are drawn from the literature on "rapid epidemiologic appraisal" (Annett H. & Rifkin S. B., 1988). The study focus on corroborating the perceptions, subjective concerns, opinions and beliefs of the Comal County key stakeholders and community participants with qualitative and quantitative indicators of health and well being. The value of this approach is to inform community leaders using a public health perspective and evidence in their decisions about priority setting and resources allocation activities for prevention of high risk behaviors and promotion of adolescent health and well being. ^
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Purpose. We performed a case-comparison study to describe the characteristics of LUS tumors and their association with risk factors for endometrial cancer. ^ Patients and Methods. From January 1996 through October 2007, 3,892 women were identified with a diagnosis of primary endometrial carcinoma or primary cervical adenocarcinoma. Pathology records from the 1,009 women who had a hysterectomy were reviewed. Subjects were included in the LUS group only if the tumor was clearly originating from the area between the lower corpus and upper cervix in the hysterectomy specimen. The LUS group was compared to all patients with endometrial corpus carcinoma who underwent hysterectomy at our institution in a 12-month period randomly selected from the study period. Risk factors for endometrial carcinoma such as body mass index (BMI) and Lynch Syndrome were assessed. Expression of estrogen receptor (ER), vimentin, carcinoembryonic antigen (CEA), p16, and human papilloma virus DNA (HPV DNA) was assessed; this panel is known to be effective in distinguishing adenocarcinomas of endometrial versus endocervical origin. Fisher's Exact, Chi-square, Mann-Whitney, and Student's t-tests were utilized for statistical analysis. ^ Results. Thirty-five of 1,009 women had endometrial carcinoma of the LUS (3.5%; 95% CI: 2–4%). Compared to patients with corpus tumors, LUS patients were younger (54.2 vs. 62.9 years, P = .001), had higher stage (P < .001), and more invasive tumors (P = .001). Preoperative diagnosis of the LUS tumors more frequently included the possibility of endocervical adenocarcinoma ( P < .001), leading to preoperative radiation therapy in 4 patients. Median BMI was similar in the LUS and corpus groups. Seventy-three percent of the available LUS tumors had a similar immunohistochemical expression pattern to conventional endometrioid adenocarcinoma. Because of the young median age for the LUS group, we performed immunohistochemistry for Lynch syndrome-associated DNA mismatch repair proteins MLH1, MSH2, MSH6, and PMS2. Microsatellite instability testing (MSI) and MLH1 promoter hypermethylation were performed when indicated. Thirty-six percent of the LUS tumors were MSI-high. Ten of thirty-five (29%) women with LUS tumors were either confirmed to have Lynch Syndrome or were strongly suspected to have Lynch Syndrome based on tissue-based molecular assays (95% CI, 16 to 45%). ^ Conclusions. Endometrial carcinoma arising in the LUS is a clinical and pathologic entity which can be diagnostically confused with cervical adenocarcinoma. In general, LUS tumors can be correctly identified as being endometrial carcinoma using the immunohistochemical panel noted above. The prevalence of Lynch Syndrome in patients with LUS tumors is much greater than that of the general endometrial cancer population (1.8%) or in endometrial cancer patients younger than 50 years of age (8–9%). Based on our results, the possibility of Lynch Syndrome should be considered in women with LUS tumors. ^
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ASISTENCIA A CONGRESOS: 17 TRABAJOS PRESENTADOS. 1- I JORNADAS TEMÁTICAS DE LITERATURA ARGENTINA CONTEMPORÁNEA: EL HUMOR EN LA LITERATURA ARGENTINA. Mendoza, del 25 al 27 de agosto de 2011 Ponencias presentadas: A) El humor de María Elena: infancia, memoria y crítica, María de las Mercedes García Saraví- María Alejandra Viana. B) Una mirada humorística en Dormir al sol, Karina Lemes y Natalia Aldana. C) De los Cambios en tu hijo adolescente a la alienación del ser. Karina Lemes. D) Isidoro Blaisten; el Humor como coartada, elaborado por Marisa Renaut; 2 - II CONGRESO INTERNACIONAL DE LITERATURA Y CULTURA ESPAÑOLAS CONTEMPORÁNEAS. Diálogos transatlánticos 3, 4 y 5 de octubre de 2011. Presentadas las siguientes ponencias: A) Laberintos y zonas de densidad: Barcelona y La Plata en dos novelas policiales de Manuel Vázquez Montalbán y Néstor Ponce. Carolina Repetto Mercedes García Saraví. B) El asedio: eco del mundo novelesco de Arturo Pérez Reverte, Haydée Borowski – Mercedes García Saraví. C) De la metaficción y otros procedimientos en La loca de la casa, Karina Beatriz Lemes. 3– XVI CONGRESO NACIONAL DE LITERATURA ARGENTINA. Resistencia, 6, 7 y 8 de octubre de 2011. Presentadas las siguientes ponencias. A) “Ceviche: una nueva cocina del policial”, María Aurelia Escalada- Mercedes García Saraví. B) Entre Santa María y Ruvichá: mundos ficcionales de Latinoamérica. Jorge Hernando Otero. C) El titirimundi de Juan Enrique Acuña: resignificaciones de un arte menor. Ana Eugenia Kushidonchi - Carina Mabel Pereira. D) Gauna: el hallazgo de un manuscrito, Mara Rabbe. E) Filiaciones en el borde. Lorca y Acuña. Karina Lemes y Natalia Aldana. F) Un Amable trasgresor de los géneros, Gabriela Román. 4- IV JORNADAS NACIONALES DE MINIFICCIÓN: HORIZONTES DE LA BREVEDAD EN EL MUNDO IBEROAMERICANO. HOMENAJE A DAVID LAGMANOVICH (1927-2010) Mendoza. 2, 3 y 4 de noviembre de 2011. Presentadas las siguientes ponencias: A) Falsificaciones, de Marco Denevi: la traducción y el apócrifo, aportes al género microrrelato Gabriela Román y Mercedes García Saraví. B) Formas breves en la narrativa de Hugo Wenceslao Amable, por Gabriela Román. Aceptado para actas. 5- IV CONGRESO CELEHIS, Mar del Plata, 7, 8 y 9 de noviembre 2011. Presentadas las siguientes ponencias. A) De la crítica y otros procedimientos en la Loca de la casa, Karina B. Lemes; b) Trayectorias y fronteras en Cádiz: El asedio (2009) de Arturo Pérez Reverte. Haydée Borowski – Mercedes García Saraví. C) Algunos mundos ficcionales de América Latina. Por Jorge Hernando Otero.// Defensa de Tesinas: Jorge Hernando Otero. Relatos ruvichenses: un espacio misionero/latinoamericano. Directora: Mercedes García Saraví. Codirectora: Karina B. Lemes. Defendida 02/11/2011, Nota: 10 (diez).
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Middle Cenozoic evolution of magmatism in the Schmidt Peninsula between 37 and 25 Ma began with eruptions of subalkaline and moderately alkaline andesite, latite, trachyandesite, and trachyrhyolite lavas and ended with subvolcanic intrusions of highly alkaline strongly undersaturated essexites. According to trace element data magmatism evolved from melting of a mantle source in the zone of ocean-continent plate convergence to small degree partial melting in the lithospheric mantle at the final stage. This succession is generally typical for Late Cenozoic continental-margin magmatism in the Southeast Russia. Similarity in the Middle and Late Cenozoic stages of magmatism is an evidence for their individual significance.
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The magnesium isotope composition of diagenetic dolomites and their adjacent pore fluids were studied in a 250 m thick sedimentary section drilled into the Peru Margin during Ocean Drilling Program (ODP) Leg 201 (Site 1230) and Leg 112 (Site 685). Previous studies revealed the presence of two types of dolomite: type I dolomite forms at ~ 6 m below seafloor (mbsf) due to an increase in alkalinity associated with anaerobic methane oxidation, and type II dolomite forms at focused sites below ~ 230 mbsf due to episodic inflow of deep-sourced fluids into an intense methanogenesis zone. The pore fluid delta 26Mg composition becomes progressively enriched in 26Mg with depth from values similar to seawater (i.e. -0.8 per mil, relative to DSM3 Mg reference material) in the top few meters below seafloor (mbsf) to 0.8 ± 0.2 per mil within the sediments located below 100 mbsf. Type I dolomites have a delta 26Mg of -3.5 per mil, and exhibit apparent dolomite-pore fluid fractionation factors of about -2.6 per mil consistent with previous studies of dolomite precipitation from seawater. In contrast, type II dolomites have delta 26Mg values ranging from -2.5 to -3.0 per mil and are up to -3.6 per mil lighter than the modern pore fluid Mg isotope composition. The enrichment of pore fluids in 26Mg and depletion in total Mg concentration below ~ 200 mbsf is likely the result of Mg isotope fractionation during dolomite formation, The 26Mg enrichment of pore fluids in the upper ~ 200 mbsf of the sediment sequence can be attributed to desorption of Mg from clay mineral surfaces. The obtained results indicate that Mg isotopes recorded in the diagenetic carbonate record can distinguish near surface versus deep formed dolomite demonstrating their usefulness as a paleo-diagenetic proxy.