987 resultados para Grosvenor, Moses Gill, 1796-1879.


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Separata de: Revista Hispánica Moderna, t.II, nº 3

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Hay un ejemplar encuadernado con: Individual noticia de todos los altares, arcos pinturas, adornos y lo mas exquisito y notable que havia en la carrera de la procession, y de las iluminaciones en general ... : (XVIII/1705).

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Microfilme. Valencia: BV, ca. 1990

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In mammals, one of the major actions of insulin-like growth factor I (IGF-I) is to increase skeletal growth by stimulating new cartilage formation. IGF-I stimulates chondrocytes in vitro to synthesize new cartilage matrix, measured by enhanced uptake of 35S-sulfate, but the addition of insulin does not produce a similar effect except when added at high concentrations. However, recent studies have shown that, in teleosts, both insulin and IGF-I are potent activators of 35S-sulfate uptake in gill cartilage. To further characterize the growth-promoting activities of these hormones in fish, we have used reverse transcriptase-linked PCR to analyze the expression of insulin receptor family genes in salmon gill cartilage. Partial cDNA sequences encoding the tyrosine kinase domains from six distinct members of the IR gene family were obtained, and sequence comparisons revealed that four of the cDNAs encoded amino acid sequences that were highly homologous to human IR whereas the encoded sequences from two of the cDNAs were more similar to the human type I IGF receptor (IGF-R). Furthermore, a comparative reverse transcriptase-linked PCR assay revealed that the four putative IR mRNAs expressed in toto in gill cartilage were 56% of that found in liver whereas the expressed amount of the two IGF-R mRNAs was 9-fold higher compared with liver. These results suggest that the chondrogenic actions of insulin and IGF-I in fish are mediated by the ligands binding to their cognate receptors. However, further studies will be required to characterize the binding properties and relative contribution of the individual IR and IGF-R genes.

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One-page letter from Croswell to William Newton, the Secretary to the Marine Society of New York, requesting a certificate to teach navigation.

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This folder contains two newspaper clippings with the proposal for Croswell's "System of Mensuration," dated October 1796, as well as a printed recommendation for the work by Professor John Kemp.

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Handwritten order to John Sale to pay scholarship funds to Moses Parsons on behalf of his son, signed by Thomas Foxcroft, Charles Chauncey, Thomas Waite, and Daniel Marsh.

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Handwritten order to John Sale to pay scholarship funds to Mercy Gill for use by her son John Gill (Harvard AB 1771), signed by Thomas Foxcroft, Charles Chauncey, Thomas Waite, Jonathan Williams, and Daniel Marsh.

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Handwritten order to John Sale to pay scholarship funds to Timothy Alden for use by his son, signed by John Clarke, David Tilden, and James Morrill.