995 resultados para Goetha, Johann Wolfgang von, 1749-1832


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tRNA binding to the ribosomal P site is dependent not only on correct codon–anticodon interaction but also involves identification of structural elements of tRNA by the ribosome. By using a phosphorothioate substitution–interference approach, we identified specific nonbridging Rp-phosphate oxygens in the anticodon loop of tRNAPhe from Escherichia coli which are required for P-site binding. Stereo-specific involvement of phosphate oxygens at these positions was confirmed by using synthetic anticodon arm analogues at which single Rp- or Sp-phosphorothioates were incorporated. Identical interference results with yeast tRNAPhe and E. coli tRNAfMet indicate a common backbone conformation or common recognition elements in the anticodon loop of tRNAs. N-ethyl-N-nitrosourea modification–interference experiments with natural tRNAs point to the importance of the same phosphates in the loop. Guided by the crystal structure of tRNAPhe, we propose that specific Rp-phosphate oxygens are required for anticodon loop (“U-turn”) stabilization or are involved in interactions with the ribosome on correct tRNA–mRNA complex formation.

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in qua itinera Regia et alia notabiliora accurate denotantur per A. Maas ; reductio mappæ haijus a majore in hanc monirem formam facta est per Iohannem Petrum van Ghelen.

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During the austral summer of 2005, the Weddell deep sea and adjacent basins were sampled in the course of the ANDEEP III project. In this study, 19 epibenthic-sledge stations are analyzed, with a focus on species diversity and distribution patterns of polychaetes. The polychaete fauna of the deep Southern Ocean has been found to be similarly speciose and diverse compared with deep-sea basins worldwide. Also, in depths below 2,000 m many polychaete species do not seem to be endemic for certain areas but are rather far spread within the Southern Ocean and beyond. Therefore, ongoing faunal exchanges between adjacent basins, even beyond the Antarctic convergence, are strongly suggested, ruling out a general isolation of the Southern Ocean deep-sea benthos. Driving forces behind species distribution patterns were investigated. The findings indicate that polychaete species' distribution in the Southern Ocean deep sea is rather dependent on local environment than depths.

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With realization of figured bass for keyboard instrument.

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Mode of access: Internet.

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Includes index.

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Text printed on back of plates.

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Includes bibliographical references.

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Complete in 2 v.

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On cover: Ministère de l'instruction publique et des beaux-arts.

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Inaug.-diss.--Tübingen. (Carolo Henrico Gros, respondent).

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Mode of access: Internet.