Ilici, hoi la villa de Elche : ilustrada con varios discursos

Palau, 158.943

Atlas geográfico universal [Texto impreso]

Varias escalas

Cédula Real

Sign. : A4

Explotación de la mina de galena argentífera "Esperanza"

Explotación de la mina de galena argentífera "Esperanza"

Proyecto de dinamo de corriente contínua

Proyecto de dinamo de corriente contínua

Catecismo o Exposicion de la Dotrina Christiana [Texto impreso]

Contiene otro catecismo del autor con paginación propia

Crida

Fecha de 1678 tomada de texto

Traduccion poetica castellana de los doze Libros de la Eneida de Virgilio Maron, Principe de los Poetas Latinos [Texto impreso]

Port. con orla tip.

A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr−/− mice

A deficiency in essential fatty acid metabolism has been reported in plasma from patients with cystic fibrosis (CF). However, its etiology and role in the expression of disease is unknown. The objective of this study was to determine whether alterations in fatty acid metabolism are specific to CF-regulated organs and whether they play a role in the expression of disease. A membrane lipid imbalance was found in ileum, pancreas, and lung from cftr−/− mice characterized by an increase in phospholipid-bound arachidonic acid and a decrease in phospholipid-bound docosahexaenoic acid (DHA). This lipid imbalance was observed in organs pathologically affected by CF including lung, pancreas, and ileum and was not secondary to impaired intestinal absorption or hepatic biosynthesis of DHA. As proof of concept, oral administration of DHA to cftr−/− mice corrected this lipid imbalance and reversed the observed pathological manifestations. These results strongly suggest that certain phenotypic manifestations of CF may result from remediable alterations in phospholipid-bound arachidonic acid and DHA levels.

Tomato Flower Abnormalities Induced by Low Temperatures Are Associated with Changes of Expression of MADS-Box Genes1

Flower and fruit development in tomato (Lycopersicon esculentum Mill.) were severely affected when plants were grown at low temperatures, displaying homeotic and meristic transformations and alterations in the fusion pattern of the organs. Most of these homeotic transformations modified the identity of stamens and carpels, giving rise to intermediate organs. Complete homeotic transformations were rarely found and always affected organs of the reproductive whorls. Meristic transformations were also commonly observed in the reproductive whorls, which developed with an excessive number of organs. Scanning electron microscopy revealed that meristic transformations take place very early in the development of the flower and are related to a significant increase in the floral meristem size. However, homeotic transformations should occur later during the development of the organ primordia. Steady-state levels of transcripts corresponding to tomato MADS-box genes TM4, TM5, TM6, and TAG1 were greatly increased by low temperatures and could be related to these flower abnormalities. Moreover, in situ hybridization analyses showed that low temperatures also altered the stage-specific expression of TM4.

Letras españolas.

Silverio Lanza.-Azoría-Pío Baroja.-Eduardo Marquinn.-Alberto Insúa.-Emilio Guanyabéns.-Miguel de Unamuno.-Vincente Medina.-Pedro Corominas.-Miguel Ciges Aparicio.-Pedro de Répide.-Los nuevos románticos (Villaespesa, Jiménez, Díez-Canedo)

Literatas españolas del siglo XIX; apuntes bibliográficos,

Mode of access: Internet.

Ideaciones; letras de América, ideas de Europa.

Mode of access: Internet.

Curso de historia de la literatura castellana; resumen de las lecciones explicadas en clase por el autor. Prólogo

"Obras del autor": 1st leaf at end of book.

Rebusco de voces castizas,

Supplements the Diccionario of the Academia española.