968 resultados para Exercise of judgment
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Sin duda alguna, el debate sobre el derecho penal del enemigo es una cuestión que está revolucionando el mundo del derecho, en general, y el derecho internacional en particular. Es un debate de actualidad que está llamando la atención de la comunidad académica, en tanto se plantea y se avizora un problema de fondo, en cuanto a la efectiva protección de los derechos humanos, por encima de un discurso de seguridad, que se viene planteando como eje central en la comunidad internacional, en la lucha contra el terrorismo y como estrategia jurídico-política al interior de Estados que dicen llamarse democráticos. Esta situación está revolucionando desde cualquier punto de vista la concepción tradicional del derecho, violentando flagrantemente la dignidad humana como eje central del Estado Social de Derecho, al poner en práctica lo que Jakobs denomina “derecho penal del enemigo”, práctica que también se viene fortaleciendo y traspasándose del ejercicio del ius puniendi de los Estados, como manifestación de soberanía, al derecho penal internacional.Abstract Without any doubt, the debate about the penal right of the enemy is a question that is revolutionizing the world of law in a general level, and international right in particular. It is a current debate that is drawing the attention of the academic community, as it poses as a basic problem: the effective protection of the human rights, over a security discourse which is presented as central in the international community in the fight against terrorism, and as a legal-political strategy to the interior of the so called democratic States. This situation is revolutionizing, from different points of view, the traditional conception of law, flagrantly violenting the human dignity as the central axis of the Social State of Right, putting in practice what Jakobs denominates “Criminal law for the enemy”. This practice is being fortified and transferring from the exercise of ius puniendi of the States, as manifestation of sovereignty, to the international penal right.
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ResumenLos derechos humanos y el desarrollo humano comparten la misma visión y objetivo: garantizar la libertad, el bienestar y la dignidad de todas las personas del mundo. Para alcanzar un desarrollohumano alto es necesario el respeto y el ejercicio eficiente de los derechos humanos, como el acceso a la educación, a los servicios de salud, a la alimentación, a un trabajo dignoy bien remunerado, a la participación activa de las decisiones económicas, entre otros. Al mismo tiempo, es importante tener un nivel de desarrollo suficiente para proporcionar y garantizarlos derechos humanos más fundamentales. En este artículo se presenta un análisis de la situación de los derechos humanos y el desarrollo humano en México. Se utilizan informes e índices de diferentes instituciones, examinando la situación específica de algunos estados. Los resultados indican que aunque México es considerado como un país de desarrollo humano “alto”, no necesariamente ha implicado que el nivel de vida de toda su población sea mejor ytampoco ha garantizado el respeto y ejercicio eficiente de los derechos humanos.Palabras clave: derechos humanos, desarrollo humano, derecho al desarrollo, México. AbstractHuman rights and human development share common visions and goals: to ensure the freedom, well-being and dignity of all the people. The achievement of a high level of human development requires both respect for and the effective exercise of fundamental human rights, including the right to: education, healthcare services, adequate food, dignified and justly remunerated work, and meaningful participation in economic decision-making, among other fundamental rights. The provision for and protection of the most basic human rights and the achievement of an acceptable level of human development are interdependent. This paper presents an analysis of human rights and the human development situation in Mexico. Reports and indices sourced from various institutions are cited and the specific conditions that exist in some Mexican states are evaluated. The results show that although Mexico has a high level of human development, it does not implies that the standard of living of all of its citizens has improved or that respect for and the effective exercise of human rights has accompaniedthis development in Mexico.Keywords: human rights, human development, right to the development, Mexico.
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Già ad uno sguardo esterno la normativa chiamata a disciplinare la condizione giuridica delle chiese cattoliche nel nostro Paese appare caratterizzata da un elevato grado di complessità: impressione che trova conferma sia con riferimento al diritto canonico, nella cui prospettiva le disposizioni appositamente dedicate ai 'loca sacra' dal Codex Iuris Canonici richiedono di essere affiancate dalle indicazioni provenienti – ai rispettivi, differenti livelli – tanto dalla Conferenza Episcopale Italiana quanto dai dicasteri della Curia romana; sia nell'ottica dell'ordinamento italiano, che agli 'edifici destinati all’esercizio pubblico del culto cattolico' riserva un'attenzione specifica, emergente nella legislazione unilaterale così come in quella pattizia. A fronte di una simile eterogeneità, sono d’altra parte note le problematiche che il tempo presente pone innanzi alle esigenze di una corretta amministrazione del patrimonio ecclesiastico – spesso pure dotato di un inestimabile valore storico-artistico –, le quali si riversano sulla preservazione stessa di tali immobili. Prendendo le mosse da questi presupposti, la trattazione si propone di effettuare una lettura sistematica delle diverse fasi in cui si articola il 'ciclo vitale' di un'ipotetica chiesa cattolica, così da ricostruire organicamente e criticamente quel quadro complessivo che permetta di formulare le soluzioni più appropriate per rispondere a questioni risalenti e sfide inedite. È quindi con questo intento che, una volta definito esattamente il concetto di chiesa-edificio, vengono ripercorsi i momenti in cui si sviluppa, anche giuridicamente, la sua esistenza: dalla pianificazione al finanziamento delle nuove costruzioni, con una speciale attenzione all'apporto che può essere offerto da parte della CEI; dagli utilizzi ammessi nel diritto canonico alle tutele garantite da parte statale; dalle misure di salvaguardia ai criteri per la loro adeguata gestione, comprendenti tanto i profili relativi alla conservazione quanto quelli riguardanti la valorizzazione; dalle implicazioni di un'eventuale riduzione a uso profano fino ai requisiti dettati per la nuova destinazione dell'immobile.
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Il lavoro affronta lo statuto penale della pubblica amministrazione, osservandolo attraverso moduli interpretativi costituzionalmente orientati e, segnatamente, quelli conformi ai principi di tassatività, offensività e proporzione. A questi se ne aggiunge un altro, ritenuto criterio immanente al titolo, dato dalla funzione amministrativa, che gioca un ruolo centrale nell’economia offensiva all’interno di tutte le fattispecie penali. L’indagine si divide in tre parti. Nella prima, si intende analizzare l’evoluzione diacronica dei modelli istituzionali di amministrazione, dovuta al mutamento radicale del rapporto tra autorità e individuo: a seguito dell’avvento dello Stato sociale e costituzionale di diritto, all’affermarsi di una concezione orizzontale del suddetto rapporto corrisponde un paradigma di amministrazione civil servant, finalisticamente orientata al soddisfacimento dei beni della vita, trovando copertura costituzionale negli articoli 97, 2 e 3 Cost. Queste vicende rappresentano il punto di partenza per ogni riflessione di sistema su questa branca di parte speciale, non potendosi pretendere di calibrare in maniera corretta l’offensività di un reato o la ragionevolezza di un’incriminazione prescindendo da un confronto con il ruolo dell’amministrazione e dalla funzione che essa svolge. Successivamente, dopo aver chiarito il significato di buon andamento e imparzialità, strumentali alla ‘buona amministrazione’, si vuole trovare un punto di equilibrio tra l’esercizio della discrezionalità, che funge da mezzo rispetto al fine del risultato amministrativo, che è ciò che qualifica oggi il modello vigente di amministrazione ‘di risultato’, e alcune disposizioni incriminatrici che possono intersecarsi con lo svolgimento fisiologico del potere discrezionale. Infine, prendendo spunto anche dal recente corso della giurisprudenza costituzionale, si vuole applicare un metodo ermeneutico costituzionalmente conforme ad una serie di fattispecie del titolo. In questo modo si eviterà di costruire un corpus di reati esangue, che riporta il diritto penale ad una superata concezione sanzionatoria, provocando un “effetto di congelamento” dell’efficienza amministrativa con pregiudizio dei diritti sottostanti.
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La ricerca affronta la questione della punizione nella prospettiva del diritto costituzionale nazionale integrata con quella del diritto europeo dei diritti dell’uomo. Nella Parte I è sostenuta la tesi secondo cui la trasformazione della Costituzione penale avviata sotto l’influsso della giurisprudenza CEDU rappresenta complessivamente un avanzamento nel processo di costituzionalizzazione del potere punitivo. Questa conclusione è supportata attraverso un confronto della filosofia costituzionale classica sulla punizione con i diversi approcci interpretativi alla Costituzione penale sviluppati durante il XX secolo (approcci tradizionale, costituzionalistico ed EDU). Nella Parte II è invece sostenuta la tesi secondo cui, nonostante gli effetti positivi dell’armonizzazione sovranazionale, lo statuto costituzionale della punizione dovrebbe comunque rimanere formalmente autonomo dal diritto EDU. Non solo, infatti, nessun paradigma dei rapporti interordinamentali finora sviluppato può giustificarne un’integrazione totale, ma essa rischierebbe anche di diminuire la normatività dell’aspetto sociale della Costituzione penale, già ipocostituzionalizzato rispetto a quello liberale. Nella Conclusione sono quindi sviluppati gli elementi fondamentali di un approccio interpretativo alternativo alla Costituzione penale che risponda meglio di quelli esistenti alle esigenze sia di garantire la massima costituzionalizzazione della punizione sia di facilitare l’integrazione sovranazionale. In base a un simile approccio costituzionalmente fondato, sostanzialista, rights-based e inclusivo di tutte le ideologie costituenti, la Costituzione potrebbe essere letta nel senso di prevedere un modello di disciplina unitario per tutte le forme di esercizio del potere punitivo (salvo quello disciplinare, distinguibile sotto l’aspetto istituzionale) caratterizzato da: una riserva di legge a intensità variabile; uno scrutinio stretto della Corte sulla giustificabilità costituzionale della pena; l’estensione dell’ambito di applicazione dei principi di colpevolezza e rieducazione; un pieno sviluppo degli aspetti di garanzia collettiva dei classici principi costituzionalpenalistici (obblighi di tutela penale e garanzia dell’effettiva collocazione della pena in capo al soggetto colpevole), nonché derivabili dall’art. 3 Cost. (proporzionalità della pena alle condizioni materiali del soggetto punito).
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Cette thèse contribue à une théorie générale de la conception du projet. S’inscrivant dans une demande marquée par les enjeux du développement durable, l’objectif principal de cette recherche est la contribution d’un modèle théorique de la conception permettant de mieux situer l’utilisation des outils et des normes d’évaluation de la durabilité d’un projet. Les principes fondamentaux de ces instruments normatifs sont analysés selon quatre dimensions : ontologique, méthodologique, épistémologique et téléologique. Les indicateurs de certains effets contre-productifs reliés, en particulier, à la mise en compte de ces normes confirment la nécessité d’une théorie du jugement qualitatif. Notre hypothèse principale prend appui sur le cadre conceptuel offert par la notion de « principe de précaution » dont les premières formulations remontent du début des années 1970, et qui avaient précisément pour objectif de remédier aux défaillances des outils et méthodes d’évaluation scientifique traditionnelles. La thèse est divisée en cinq parties. Commençant par une revue historique des modèles classiques des théories de la conception (design thinking) elle se concentre sur l’évolution des modalités de prise en compte de la durabilité. Dans cette perspective, on constate que les théories de la « conception verte » (green design) datant du début des années 1960 ou encore, les théories de la « conception écologique » (ecological design) datant des années 1970 et 1980, ont finalement convergé avec les récentes théories de la «conception durable» (sustainable design) à partir du début des années 1990. Les différentes approches du « principe de précaution » sont ensuite examinées sous l’angle de la question de la durabilité du projet. Les standards d’évaluation des risques sont comparés aux approches utilisant le principe de précaution, révélant certaines limites lors de la conception d’un projet. Un premier modèle théorique de la conception intégrant les principales dimensions du principe de précaution est ainsi esquissé. Ce modèle propose une vision globale permettant de juger un projet intégrant des principes de développement durable et se présente comme une alternative aux approches traditionnelles d’évaluation des risques, à la fois déterministes et instrumentales. L’hypothèse du principe de précaution est dès lors proposée et examinée dans le contexte spécifique du projet architectural. Cette exploration débute par une présentation de la notion classique de «prudence» telle qu’elle fut historiquement utilisée pour guider le jugement architectural. Qu’en est-il par conséquent des défis présentés par le jugement des projets d’architecture dans la montée en puissance des méthodes d’évaluation standardisées (ex. Leadership Energy and Environmental Design; LEED) ? La thèse propose une réinterprétation de la théorie de la conception telle que proposée par Donald A. Schön comme une façon de prendre en compte les outils d’évaluation tels que LEED. Cet exercice révèle cependant un obstacle épistémologique qui devra être pris en compte dans une reformulation du modèle. En accord avec l’épistémologie constructiviste, un nouveau modèle théorique est alors confronté à l’étude et l’illustration de trois concours d'architecture canadienne contemporains ayant adopté la méthode d'évaluation de la durabilité normalisée par LEED. Une série préliminaire de «tensions» est identifiée dans le processus de la conception et du jugement des projets. Ces tensions sont ensuite catégorisées dans leurs homologues conceptuels, construits à l’intersection du principe de précaution et des théories de la conception. Ces tensions se divisent en quatre catégories : (1) conceptualisation - analogique/logique; (2) incertitude - épistémologique/méthodologique; (3) comparabilité - interprétation/analytique, et (4) proposition - universalité/ pertinence contextuelle. Ces tensions conceptuelles sont considérées comme autant de vecteurs entrant en corrélation avec le modèle théorique qu’elles contribuent à enrichir sans pour autant constituer des validations au sens positiviste du terme. Ces confrontations au réel permettent de mieux définir l’obstacle épistémologique identifié précédemment. Cette thèse met donc en évidence les impacts généralement sous-estimés, des normalisations environnementales sur le processus de conception et de jugement des projets. Elle prend pour exemple, de façon non restrictive, l’examen de concours d'architecture canadiens pour bâtiments publics. La conclusion souligne la nécessité d'une nouvelle forme de « prudence réflexive » ainsi qu’une utilisation plus critique des outils actuels d’évaluation de la durabilité. Elle appelle une instrumentalisation fondée sur l'intégration globale, plutôt que sur l'opposition des approches environnementales.
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At a time of crisis – a true state of emergency – both the Court of Justice of the European Union and the German Federal Constitutional Court have failed the rule of law in Europe. Worse still, in their evaluation of the ersatz crisis law, which has been developed in response to financial and sovereign debt crises, both courts have undermined constitutionality throughout Europe. Each jurisdiction has been implicated within the techocratisation of democratic process. Each Court has contributed to an incremental process of the undermining of the political subjectivity of European Citizens. The results are depressing for lawyers who are still attached to notions of constitutionality. Yet, we must also ask whether the Courts could have acted otherwise. Given the original flaws in the construction of Economic and Monetary Union, as well as the politically pre-emptive constraints imposed by global financial markets, each Court might thus be argued to have been forced to suspend immediate legality in a longer term effort to secure the character of the legal jurisdiction as a whole. Crisis can and does defeat the law. Nevertheless, what continues to disturb is the failure of law in Europe to open up any perspective for a return to normal constitutionality post crisis, as well as its apparent inability to give proper and honest consideration to the hardship now being experienced by millions of Europeans within crisis. This contribution accordingly seeks to reimagine each Judgment in a language of legal honesty. Above all, this contribution seeks to suggest a new form of post-national constitutional language; a language which takes as its primary function, proper protection of democratic process against the ever encroaching powers of a post-national executive power. This contribution forms a part of an on-going effort to identify a new basis for the legitimacy of European Law, conducted jointly and severally with Christian Joerges, University of Bremen and Hertie School of Government, Berlin. Differences do remain in our theoretical positions; hence this individual essay. Nevertheless, the congruence between pluralist and conflict of law approaches to the topic are also readily apparent. See, for example, Everson & Joerges (2013).
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To evaluate the effects of acute exercise on the TRB3 protein levels and interaction between TRB3/Akt proteins in the hypothalamus of obese rats. In addition, we evaluated the relationship between TRB3 and endoplasmic reticulum stress (ER stress) and verified whether an acute exercise session is able to influence these processes. In the first part of the study, the rats were divided into three groups: control (lean) - fed with a standard rodent chow, DIO - fed with a high fat diet and DIO submitted to a swimming acute exercise protocol (DIO-EXE). In the second part of the study, we used other three groups: control (lean) receiving an intracerebroventricular (i.c.v.) infusion of vehicle, lean receiving an i.c.v. infusion of thapsigargin, and lean receiving an i.c.v infusion of thapsigargin and performing an acute exercise session. Four hours after the exercise session, the food intake was measured and the hypothalamus was dissected and separated for subsequent protein analysis by immunoblotting and Real Time PCR. The acute exercise session reduced the TRB3 protein levels, disrupted the interaction between TRB3/Akt proteins, increased the phosphorylation of Foxo1 and restored the anorexigenic effects of insulin in the hypothalamus of DIO rats. Interestingly, the suppressive effects of acute exercise on TRB3 protein levels may be related, at least in part, to the decrease of ER stress (evaluated though pancreatic ER kinase phosphorylation - pPERK and C/EBP homologous protein - CHOP protein levels) in the hypothalamus. In conclusion, the reduction of hypothalamic TRB3 protein levels mediated by exercise may be associated with the reduction of ER stress. These data provided a new mechanism by which an acute exercise session improves insulin sensitivity in hypothalamus and restores food intake control in obesity.
Exercise Increases Pancreatic β-cell Viability In A Model Of Type 1 Diabetes Through Il-6 Signaling.
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Type 1 diabetes (T1D) is provoked by an autoimmune assault against pancreatic β cells. Exercise training enhances β-cell mass in T1D. Here, we investigated how exercise signals β cells in T1D condition. For this, we used several approaches. Wild-type and IL-6 knockout (KO) C57BL/6 mice were exercised. Afterward, islets from control and trained mice were exposed to inflammatory cytokines (IL-1β plus IFN-γ). Islets from control mice and β-cell lines (INS-1E and MIN6) were incubated with serum from control or trained mice or medium obtained from 5-aminoimidazole-4 carboxamide1-β-d-ribofuranoside (AICAR)-treated C2C12 skeletal muscle cells. Subsequently, islets and β cells were exposed to IL-1β plus IFN-γ. Proteins were assessed by immunoblotting, apoptosis was determined by DNA-binding dye propidium iodide fluorescence, and NO(•) was estimated by nitrite. Exercise reduced 25, 75, and 50% of the IL-1β plus IFN-γ-induced iNOS, nitrite, and cleaved caspase-3 content, respectively, in pancreatic islets. Serum from trained mice and medium from AICAR-treated C2C12 cells reduced β-cell death, induced by IL-1β plus IFN-γ treatment, in 15 and 38%, respectively. This effect was lost in samples treated with IL-6 inhibitor or with serum from exercised IL-6 KO mice. In conclusion, muscle contraction signals β-cell survival in T1D through IL-6.-Paula, F. M. M., Leite, N. C., Vanzela, E. C., Kurauti, M. A., Freitas-Dias, R., Carneiro, E. M., Boschero, A. C., and Zoppi, C. C. Exercise increases pancreatic β-cell viability in a model of type 1 diabetes through IL-6 signaling.
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The present study aimed to investigate the effects of the interaction between the abusive use of nandrolone decanoate (ND) and physical activity on the prostate structure of adult and older rats. We evaluated whether the use of ND, associated or not with physical exercise during the post-pubertal stage, interferes with the morphophysiology of the prostate. Fifty-six male Sprague-Dawley rats were divided into eight groups. The animals were treated for eight weeks and divided into sedentary and trained groups, with or without ND use. Four groups were sacrificed 48 h after the end of the eight week experiment (adult groups), and four other groups were sacrificed at 300 days of age (older groups). The prostate was collected and processed for stereological and histopathological analysis and for the expression of AQP1 and VEGF by the Western blotting technique. Both ND and physical activity altered the ventral prostate structure of the rats; the AQP1 and VEGF expression increased in young animals subjected to physical exercise. Thus, it was concluded that the use of ND, associated or not with exercise during the post-pubertal stage, interferes with the morphophysiology of the prostate.
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Universidade Estadual de Campinas . Faculdade de Educação Física
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Universidade Estadual de Campinas . Faculdade de Educação Física
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The aim of this study was to test the hypothesis of differences in performance including differences in ST-T wave changes between healthy men and women submitted to an exercise stress test. Two hundred (45.4%) men and 241 (54.6%) women (mean age: 38.7 ± 11.0 years) were submitted to an exercise stress test. Physiologic and electrocardiographic variables were compared by the Student t-test and the chi-square test. To test the hypothesis of differences in ST-segment changes, data were ranked with functional models based on weighted least squares. To evaluate the influence of gender and age on the diagnosis of ST-segment abnormality, a logistic model was adjusted; P < 0.05 was considered to be significant. Rate-pressure product, duration of exercise and estimated functional capacity were higher in men (P < 0.05). Sixteen (6.7%) women and 9 (4.5%) men demonstrated ST-segment upslope ≥0.15 mV or downslope ≥0.10 mV; the difference was not statistically significant. Age increase of one year added 4% to the chance of upsloping of segment ST ≥0.15 mV or downsloping of segment ST ≥0.1 mV (P = 0.03; risk ratio = 1.040, 95% confidence interval (CI) = 1.002-1.080). Heart rate recovery was higher in women (P < 0.05). The chance of women showing an increase of systolic blood pressure ≤30 mmHg was 85% higher (P = 0.01; risk ratio = 1.85, 95%CI = 1.1-3.05). No significant difference in the frequency of ST-T wave changes was observed between men and women. Other differences may be related to different physical conditioning.
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Background: The Borg Scale may be a useful tool for heart failure patients to self-monitor and self-regulate exercise on land or in water (hydrotherapy) by maintaining the heart rate (HR) between the anaerobic threshold and respiratory compensation point. Methods and Results: Patients performed a cardiopulmonary exercise test to determine their anaerobic threshold/respiratory compensation points. The percentage of the mean HR during the exercise session in relation to the anaerobic threshold HR (%EHR-AT), in relation to the respiratory compensation point (%EHR-RCP), in relation to the peak HR by the exercise test (%EHR-Peak) and in relation to the maximum predicted HR (%EHR-Predicted) was calculated. Next, patients were randomized into the land or water exercise group. One blinded investigator instructed the patients in each group to exercise at a level between ""relatively easy and slightly tiring"". The mean HR throughout the 30-min exercise session was recorded. The %EHR-AT and %EHR-Predicted did not differ between the land and water exercisegroups, but they differed in the %EHR-RCP (95 +/- 7 to 86 +/- 7. P<0.001) and in the %EHR-Peak (85 +/- 8 to 78 +/- 9, P=0.007). Conclusions: Exercise guided by the Borg scale maintains the patient's HR between the anaerobic threshold and respiratory compensation point (ie, in the exercise training zone). (Circ J 2009; 73: 1871-1876)
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Souza MA, Souza MH, Palheta RC Jr, Cruz PR, Medeiros BA, Rola FH, Magalhaes PJ, Troncon LE, Santos AA. Evaluation of gastrointestinal motility in awake rats: a learning exercise for undergraduate biomedical students. Adv Physiol Educ 33: 343-348, 2009; doi: 10.1152/advan.90176.2008.-Current medical curricula devote scarce time for practical activities on digestive physiology, despite frequent misconceptions about dyspepsia and dysmotility phenomena. Thus, we designed a hands-on activity followed by a small-group discussion on gut motility. Male awake rats were randomly submitted to insulin, control, or hypertonic protocols. Insulin and control rats were gavage fed with 5% glucose solution, whereas hypertonic-fed rats were gavage fed with 50% glucose solution. Insulin treatment was performed 30 min before a meal. All meals (1.5 ml) contained an equal mass of phenol red dye. After 10, 15, or 20 min of meal gavage, rats were euthanized. Each subset consisted of six to eight rats. Dye recovery in the stomach and proximal, middle, and distal small intestine was measured by spectrophotometry, a safe and reliable method that can be performed by minimally trained students. In a separate group of rats, we used the same protocols except that the test meal contained (99m)Tc as a marker. Compared with control, the hypertonic meal delayed gastric emptying and gastrointestinal transit, whereas insulinic hypoglycemia accelerated them. The session helped engage our undergraduate students in observing and analyzing gut motor behavior. In conclusion, the fractional dye retention test can be used as a teaching tool to strengthen the understanding of basic physiopathological features of gastrointestinal motility.