Utilization of Ethyl Cyanoacrylate and 2-Octyl Cyanoacrylate Adhesives for Autogenous Bone Graft Fixation: Histomorphometric Study in Rats

The present study analyzes the repair process of autogenous bone graft in a block fixed with ethyl cyanoacrylate and 2-octyl cyanoacrylate adhesives in rat calvaria. Forty-eight rats, divided into 3 groups, received round osteotomies at the right parietal bone for the attainment of autogenous bone graft fragment, which was fixed at the opposite side to the donor site with ethyl cyanoacrylate (ethyl group) and 2-octyl cyanoacrylate (octyl group) adhesives. In the control group, bone fragment was only juxtaposed at the parietal bone surface without any fixation material. The animals were euthanized after 10 and 60 postoperative days. The calvariae were processed in a laboratory for the attainment of slides stained through the hematoxylin and eosin technique for histological and histometric analysis. The qualitative analysis showed a discrete inflammatory infiltrate in the control group and moderate inflammatory infiltrate in the ethyl and octyl groups at the 10-day period, which remained at the 60-day period, mainly in the octyl group. The bone fragment remained bonded to the recipient site through the adhesive, but graft incorporation was not observed in any of the specimens. Resorption was higher in the octyl group followed by the ethyl and control groups, both at the 10-and 60-day periods, but with no statistical significance (P < .05). Although promoting graft fixation and its maintenance at the recipient site, both studied adhesives did not allow the graft incorporation, producing a localized and discrete inflammatory reaction, which persisted at 60 days, being more intense in the octyl cyanoacrylate group.

Endotélio da córnea e facoemulsificação em cães

This study aims, by a literature review, to evaluate the effects of the phacoemulsification surgery into the endothelial cells of the cornea, especially on dogs. The phacoemulsification is a surgical technique of cataract surgery, and presents a series of factors pre, trans and post operation that can affect the cornea endothelium. Knowing that the cornea transparency is essential to the preservation of the visual acuity, and that the endothelium cells do not demonstrate an adequate regeneration, it is important to the surgeon to be aware of these factors in order to avoid or to minimize them. Among then can be mentioned: previous diseases, surgical and chemical trauma, intra-ocular lens, uveitis etc. As consequence, a reduction on the number of endothelium cells and edema can be observed, which can lead to a loss of vision by definitive cornea opacity or to late visual recuperation

Patogenicidade do isolado Lins de Trypanosoma vivax em bovinos natural e experimentalmente infectados

Pós-graduação em Medicina Veterinária - FCAV

Parâmetros oftálmicos em espécimes de Cuniculus paca criadas em cativeiro

Pós-graduação em Cirurgia Veterinária - FCAV

Efeitos da injeção de lidocaína 1% sem conservantes, em olhos de coelhos da raça Nova Zelândia Branco com uveíte

Pós-graduação em Cirurgia Veterinária - FCAV

Omento alógeno de coelho (tecido ou cultivo) associado a membrana amniótica de cão na ceratoplastia lamelar em coelhos

Pós-graduação em Cirurgia Veterinária - FCAV

Expressão de matriz metaloproteinases e PCNA me úlceras corneais profundas, induzidas em coelhos, tratadas com plasma rico em plaquetas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)